ExploreContains growth curve data such as Glucose uptake rate, lactate and acetate production at different time points.
Growth curve A was used train the model with external glucose concentration as well as external lactate, acetate concentration and estimated glucose acetate and lactate flux
SEEK ID: https://fairdomhub.org/data_files/1705?version=1
Filename:
Todos datos growth_curve(with uptake rates).xls
Format: Spreadsheet
Size: 593 KB
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Creators and Submitter
Views: 821 Downloads: 38
Created: 1st May 2017 at 15:08
Last updated: 14th Jan 2019 at 16:00
Last used: 20th Feb 2021 at 05:56
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https://orcid.org/0000-0001-7049-5334I am a researcher (PhD student) working at Wageningen University & Research as bioinformatician and modeller. I am working as part of the MycoSynVac (http://www.mycosynvac.eu/) project on dynamic modelling of central carbon metabolism in M. pneumoniae, to be extended to full dynamic modelling of metabolism to be implemented in a whole cell model.
I am also looking into possibilities to improve standards in model generation using semantic technologies, improving automatic generation, annotation
...
The MycoSynVac project AIMS at using cutting-edge synthetic biology methodologies to engineer Mycoplasma pneumoniae as a universal chassis for vaccination.
Designing a universal Mycoplasma chassis that can be deployed as single- or multi-vaccine in a range of animal hosts. Annually, infections caused by Mycoplasma species in poultry, cows, and pigs result in multimillion Euro losses in the USA and Europe.
There is no effective vaccination against many Mycoplasmas that infect pets, humans and farm
...
Programme: Independent Projects
Public web page: http://www.mycosynvac.eu/
1. To develop a whole-cell dynamic model framework of the metabolism of M. pneumoniae
2. To build upon M. pneumoniae models to develop a genome-scale, constraint-based model of M.
hyopneumoniae for vaccine optimization
3. To deploy the metabolic model(s) to: 1) the rational design and optimization of the vaccine chassis; 2)
aid the development of a higher-growth rate chassis; 3) assist the development of a nutrient optimized a
serum-free growth medium and; 4) assess, at genome scale, the metabolic
...
Snapshots: Snapshot 1, Snapshot 2, Snapshot 3
Internal metabolites concentrations for time series data (not pulse experiments) and for mutant OE, KO mutants and perturbations
External metabolite concentrations for time series data (not pulse experiments) and for mutant OE, KO mutants and perturbations
Mutant (OE, KO, perturbation) metabolite measurements
Person responsible: Niels Zondervan
Snapshots: No snapshots
Measurements of external metabolites based on growth curve data.
Flux estimates for uptake of external metabolites such as glucose and production rates for external metabolites lactate and acetate
Submitter: Niels Zondervan
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
