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SEEK ID: https://fairdomhub.org/investigations/595

Projects: MetNet

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Creators and Submitter

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Charles Demurjian

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Charles Demurjian

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Views: 473

Created: 17th Feb 2023 at 17:29

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Charles Demurjian

Projects: IMPAcTB, MIT SRP, MetNet, Endometriosis

Institutions: Massachusetts Institute of Technology

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Metastasis Network

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Projects: MetNet

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Programme: Metastasis Network

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Impact of fibrinogen, fibrin thrombi and thrombin on cancer cell extravasation using in vitro microvascular networks

MetNet

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Charles Demurjian

Emmanouil Angelidakis, Sophia Chen, Shun Zhang, Zhengpeng Wan, Roger D. Kamm, Sarah E. Shelton

Link to Paper: https://doi.org/10.1002/adhm.202202984

A bidirectional association exists between metastatic dissemination and the hypercoagulable state associated with many types of cancer. As such, clinical studies have provided evidence that markers associated with elevated levels of coagulation and fibrinolysis correlate with decreased patient survival. However, ...