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Created: 16th May 2023 at 18:10
Last updated: 16th May 2023 at 18:25
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Version 1 (earliest) Created 16th May 2023 at 18:10 by Charles Demurjian
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Projects: Hi-IMPAcTB, MIT SRP, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC)
Institutions: Massachusetts Institute of Technology
Programme: Metastasis Network
Public web page: Not specified
Organisms: Not specified
Submitter: Charles Demurjian
Studies: Impact of fibrinogen, fibrin thrombi and thrombin on cancer cell extrava..., Personalized Vascularized Models of Breast Cancer Desmoplasia Reveal Bio..., Utilizing convolutional neural networks for discriminating cancer and st...
Assays: Cancer Cell Extravasation Analysis - Data Linked, Cell Culture and Tumor Spheroid Creation - Metadata, Clot Modeling Analysis - Data Linked, Convolutional Neural Network - Data Linked, Device Creation - Metadata, Device Creation - Metadata, Device Imaging - Data Linked, Device Imaging - Data Linked, Device Imaging - Metadata, Flow Cytometry - Data Linked, Flow Cytometry Analysis - Data Linked, Imaging Analysis - Data Attached, Microfluidic Device Creation - Metadata, Permeability Analysis - Data Linked, Tumoroid Formation - Metadata
Snapshots: No snapshots
Giovanni S. Offeddu#, Elena Cambria#, Sarah E. Shelton, Kristina Haase, Zhengpeng Wan, Luca Possenti, Huu Tuan Nguyen, Mark R. Gillrie, Dean Hickman, Charles G. Knutson, and Roger D. Kamm
Abstract: Desmoplasia in breast cancer leads to heterogeneity in physical properties of the tissue, resulting in disparities in drug delivery and treatment efficacy among patients, thus contributing to high disease mortality. Personalized in vitro breast cancer models hold ...
Submitter: Charles Demurjian
Investigation: MetNet
Assays: Device Creation - Metadata, Device Imaging - Metadata, Imaging Analysis - Data Attached, Tumoroid Formation - Metadata
Snapshots: No snapshots
Huu Tuan Nguyen, Nicholas Pietraszek, Sarah E. Shelton, Kwabena Arthur, Roger D. Kamm
Link to Paper:
Abstract: Significance: Accurate cell segmentation and classification in 3 dimensional (3D) images are vital for studying live cell behavior and drug responses in 3D tissue culture. Evaluating diverse cell populations in 3D cell culture over time necessitates non-toxic staining methods, as specific fluorescence tags may not be suitable and immunofluorescence ...
Submitter: Charles Demurjian
Investigation: MetNet
Assays: Cell Culture and Tumor Spheroid Creation - Metadata, Convolutional Neural Network - Data Linked, Device Creation - Metadata, Device Imaging - Data Linked
Snapshots: No snapshots
Emmanouil Angelidakis, Sophia Chen, Shun Zhang, Zhengpeng Wan, Roger D. Kamm, Sarah E. Shelton
Link to Paper: https://doi.org/10.1002/adhm.202202984
A bidirectional association exists between metastatic dissemination and the hypercoagulable state associated with many types of cancer. As such, clinical studies have provided evidence that markers associated with elevated levels of coagulation and fibrinolysis correlate with decreased patient survival. However, ...
Submitter: Charles Demurjian
Investigation: MetNet
Assays: Cancer Cell Extravasation Analysis - Data Linked, Clot Modeling Analysis - Data Linked, Device Imaging - Data Linked, Flow Cytometry - Data Linked, Flow Cytometry Analysis - Data Linked, Microfluidic Device Creation - Metadata, Permeability Analysis - Data Linked
Snapshots: No snapshots
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MetNet
Organisms: No organisms
SOPs: P.KAM-230131-V1_Cell-culture.docx, P.KAM-230131-V1_OOC-protocol-device-and-network...
Data files: CEL-samples-publish2023-05-16_11-33.xlsx, OOC-samples-publish2023-05-16_11-38.xlsx
Snapshots: No snapshots
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MetNet
Organisms: No organisms
SOPs: P.KAM-230131-V1_Cell-culture.docx, P.KAM-240227-V1_Cell-Culture-CNN.docx
Data files: samples-publish2024-03-05-CEL.xlsx
Snapshots: No snapshots
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MetNet
Organisms: No organisms
SOPs: P.KAM-230131-V1_Cell-culture.docx, P.KAM-240321-V1_Vascularized-Tumoroid-Formation...
Data files: samples-publish2024-03-22-CEL.xlsx
Snapshots: No snapshots