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SEEK ID: https://fairdomhub.org/investigations/455

Projects: MIT SRP

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Creators and Submitter

Creator

Dikshant Pradhan

Submitter

Dikshant Pradhan

Activity

Views: 774

Created: 29th Mar 2021 at 18:33

Related items

People (1)
Programmes (1)
Projects (1)
Studies (4)
Assays (24)
Data files (36)
SOPs (19)
Publications (1)

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Dikshant Pradhan

Projects: IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology

Advanced Programmes list for this Investigation with search and filtering ...

MIT Superfund Research

No description specified

Projects: MIT SRP

Web page: https://superfund.mit.edu/

Advanced Projects list for this Investigation with search and filtering ...

MIT SRP

No description specified

Programme: MIT Superfund Research

Public web page: Not specified

Organisms: Not specified

Advanced Studies list for this Investigation with search and filtering ...

Interaction of N-Nitroamines with Bincuelar Copper Complexs for Luminsecent Detection

MIT SRP

All creators

Charles Demurjian

Haosheng Feng, Shao-Xiong Lennon Luo, Robert G Croy, John M. Essigmann, Timothy M. Swager

https://doi.org/10.1039/D2DT03848J

Cu(I) from tetrakis(acetonitrile)copper(I) hexafluorophosphate ([Cu(MeCN)4]PF6) was complexed with five structurally related phosphines containing N-heterocycles. The interactions between the resulting complexes and some N-nitrosamines were studied using X-ray crystallography as well as emission spectroscopy. Upon complexation, three ...

Submitter: Charles Demurjian

Investigation: MIT SRP

Assays: Absorption and Emission Spectroscopy - Data Linked, Absorption and Emission Spectroscopy Analysis - Data Linked, Chemical Synthesis - Metadata, Crystallography - Data Linked, Electron Paramagnetic Resonance - Data Linked, High Resolution Mass Spectra - Data Linked, High Resolution Mass Spectra Analysis - Data Linked, Nuclear Magnetic Resonance Spectroscopy - Data Linked, Nuclear Magnetic Resonance Spectroscopy Analysis - Data Linked, X-ray Photoelectron Spectroscopy - Data Linked

Snapshots: Snapshot 1

Created: 24th Feb 2023 at 22:32, Last updated: 16th Mar 2023 at 18:21

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents

MIT SRP

All creators

Charles Demurjian

Amanda L. Armijo, Pennapa Thongaram, Bogdan I. Fedeles, Judy Yau, Jennifer E Kay, Joshua J. Corrigan, Marisa Chancharoen, Supawadee Chawanthayatham, Leona D. Samson, Sebastian E. Carrasco, Bevin P. Engelward, James G. Fox, Robert G. Croy & John M. Essigmann

DNA-methylating environmental carcinogens such as N-nitrosodimethylamine (NDMA) and certain alkylators used in chemotherapy form O6-methylguanine (m6G) as a functionally critical intermediate. NDMA ...

Submitter: Charles Demurjian

Investigation: MIT SRP

Assays: Extraction and Library Creation - Metadata, GPT Assay - Data Attached, Genome Alignment - Data Linked, Illumina Sequencing - Data Linked, Mutational Spectral Analysis - Data Attached, Necropsy - Metadata

Snapshots: Snapshot 1

Created: 9th Feb 2023 at 22:50, Last updated: 8th Mar 2023 at 23:25

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

MIT SRP

All creators

Dikshant Pradhan

Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward doi: https://doi.org/10.1101/2021.01.12.426356

Link to all of the Imaging done in this study: https://omero.mit.edu/webclient/?show=project-153 ...

Submitter: Dikshant Pradhan

Investigation: MIT SRP

Assays: GPT Assay – Data Attached, Mass Spectrometry Processing – Data Linked, Mass Spectrometry – Data Linked, Mouse Necropsy – Metadata, RaDR Image Machine Learning Analysis – Data Attached, Tissue Imaging – Metadata, Tissue Lysis – Metadata

Snapshots: Snapshot 1, Snapshot 2, Snapshot 3, Snapshot 4

DOI: 10.15490/fairdomhub.1.study.834.4

Created: 29th Mar 2021 at 18:34, Last updated: 15th Dec 2022 at 21:19

Benthic fluxes of fluorescent dissolved organic material, salt and heat measured by multiple-sensor aquatic eddy covariance

MIT SRP

All creators

Huiming Ding

Irene Hu and Harold Hemond

https://doi.org/10.3390/

Aquatic eddy covariance (AEC) is an in situ technique for measuring fluxes in marine and freshwater systems based on the covariance of velocity and concentration measurements. Here, development of a fast multiple-channel sensor (FACT) enables the use of AEC for measurement of benthic fluxes of fluorescent dissolved organic material, salt, and heat at three distinct sites in Massachusetts, USA, including the Connecticut River, the Concord River, ...

Submitter: Huiming Ding

Investigation: MIT SRP

Assays: Field Water Sensor Run

Snapshots: Snapshot 1

DOI: 10.15490/fairdomhub.1.study.1083.1

Created: 24th Aug 2022 at 16:12, Last updated: 24th Aug 2022 at 19:48

Showing 20 out of a possible 24 items Advanced Assays list for this Investigation with search and filtering ...

Mouse Necropsy – Metadata

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: P.ENG-200806-V2_Short-Term-Collection-at-Necrop..., P.ENG-201008-V1_Med-Term-Collection-at-Necropsy...

Data files: samples-publish2021-03-30_16-25.xlsx, samples-publish2021-03-30_17-38.xlsx, samples-publish2021-09-20_22-36.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 18:35, Last updated: 10th Jan 2022 at 17:47

Tissue Imaging – Metadata

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_16-04.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 19:57, Last updated: 10th Jan 2022 at 17:49

Mass Spectrometry – Data Linked

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_15-51.xlsx, samples-publish2021-03-30_17-07.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 20:00, Last updated: 10th Jan 2022 at 17:38

Mass Spectrometry Processing – Data Linked

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_14-31.xlsx, samples-publish2021-03-30_15-51.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 20:00, Last updated: 10th Jan 2022 at 17:37

Tissue Lysis – Metadata

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_17-07.xlsx

Snapshots: No snapshots

Created: 30th Mar 2021 at 18:57, Last updated: 10th Jan 2022 at 17:41

GPT Assay – Data Attached

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: P.ESS-201123-V1_gpt-NextGen-Protocol.pdf

Data files: 10.1016.j.celrep.2021.108864_GPT_assay, D.GPT-samples-publish2021-12-13_23-22.xlsx

Snapshots: No snapshots

Created: 20th Sep 2021 at 15:55, Last updated: 10th Jan 2022 at 17:58

RaDR Image Machine Learning Analysis – Data Attached

MIT SRP

All creators

Dikshant Pradhan

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: A.IMG-samples-publish2021-12-13_22-22.xlsx, WAD_RaDR_roi_extraction_10.1016.j.celrep.2021.1..., samples-publish2021-03-30_16-04.xlsx

Snapshots: No snapshots

Created: 13th Dec 2021 at 15:19, Last updated: 10th Jan 2022 at 18:04

Field Water Sensor Run

MIT SRP

All creators

Jake Schissel

No description specified

Submitter: Jake Schissel

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Benthic fluxes of fluorescent dissolved organic...

Organisms: No organisms

SOPs: P.HEM-220913-V2_20210513_fieldworkOperatingProc..., P.HEM-220913-V2_20210520_fieldworkOperatingProc..., P.HEM-220913-V2_20210610_fieldworkOperatingProc...

Data files: D.SNSR-samples-publish2022-10-11_18-50.xlsx, LOC-samples-publish2022-10-11_18-37.xlsx

Snapshots: No snapshots

Created: 11th Oct 2022 at 15:51, Last updated: 25th Oct 2022 at 16:21

Necropsy - Metadata

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: No SOPs

Data files: MUS-samples-publish2023-03-08_12-23.xlsx, PAV-samples-publish2023-03-08_12-32.xlsx, TIS-samples-publish2023-03-08_12-40.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:17, Last updated: 8th Mar 2023 at 23:52

Chemical Synthesis - Metadata

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230223-V1_synthesis-protocol

Data files: CHM-samples-publish2023-03-16_10-12.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:49, Last updated: 16th Mar 2023 at 18:22

Extraction and Library Creation - Metadata

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ENG-200806-V2_Short-Term-Collection-at-Necrop..., P.ENG-200831-V1_NDMA-Juvenile-Mouse-Injection-P..., P.ENG-220105-V1_NDMA-Juvenile-Mouse-Single-Inje..., P.ENG-220105-V1_Tissue-Collection-at-Necropsy-(..., P.ESS-230303-V2_Cell-culture.docx

Data files: CEL-samples-publish2023-03-08_11-57.xlsx, DNA-samples-publish2023-03-08_13-15.xlsx, TIS-samples-publish2023-03-08_12-40.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:22, Last updated: 8th Mar 2023 at 23:52

Absorption and Emission Spectroscopy - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230302-V1_Fluorescence-and-XPS

Data files: CHM-samples-publish2023-03-16_10-12.xlsx, D.SPC-samples-publish2023-03-16_10-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:50, Last updated: 16th Mar 2023 at 18:22

GPT Assay - Data Attached

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ESS-201123-V1_gpt-NextGen-Protocol-.pdf

Data files: D.GPT-samples-publish2023-03-08_13-55.xlsx, DNA-samples-publish2023-03-08_13-15.xlsx, NDMA_in-vivo_gpt_data.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:24, Last updated: 8th Mar 2023 at 23:52

Absorption and Emission Spectroscopy Analysis - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: No SOPs

Data files: A.SPC-samples-publish2023-03-16_10-25.xlsx, D.SPC-samples-publish2023-03-16_10-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:56, Last updated: 16th Mar 2023 at 18:22

Illumina Sequencing - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ESS-230308-V2_Duplex-sequencing.docx

Data files: D.SEQ-samples-publish2023-03-24_13-17.xlsx, DNA-samples-publish2023-03-08_13-15.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:15, Last updated: 24th Mar 2023 at 19:30

Nuclear Magnetic Resonance Spectroscopy - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230302-V1_NMR

Data files: CHM-samples-publish2023-03-16_10-12.xlsx, D.NMR-samples-publish2023-03-16_11-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:52, Last updated: 16th Mar 2023 at 18:22

Genome Alignment - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ESS-230303-V1_Data-processing-(alignment).docx

Data files: A.ALN-samples-publish2023-03-24_14-05.xlsx, D.SEQ-samples-publish2023-03-24_13-17.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:25, Last updated: 24th Mar 2023 at 20:07

Nuclear Magnetic Resonance Spectroscopy Analysis - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: No SOPs

Data files: A.NMR-samples-publish2023-03-16_11-39.xlsx, D.NMR-samples-publish2023-03-16_11-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:56, Last updated: 16th Mar 2023 at 18:22

Mutational Spectral Analysis - Data Attached

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ESS-230303-V1_Data-processing-(alignment).docx

Data files: A.MUSP-samples-publish2023-03-08_17-46.xlsx, Armijo-NDMA_HRMS-data.xlsx

Snapshots: No snapshots

Created: 8th Mar 2023 at 19:43, Last updated: 8th Mar 2023 at 23:52

High Resolution Mass Spectra - Data Linked

MIT SRP

All creators

Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230302-V1_Jeol-Accu-ToF_05252022, P.SWA-230302-V1_Mass-Spectrometry

Data files: CHM-samples-publish2023-03-16_10-12.xlsx, D.MSP-samples-publish2023-03-16_11-35.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:52, Last updated: 16th Mar 2023 at 18:22

Showing 20 out of a possible 36 items Advanced Data files list for this Investigation with search and filtering ...

D.SEQ-samples-publish2023-03-24_13-17.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Genome Alignment - Data Linked, Illumina Sequencing - Data Linked

Download

Created: 24th Mar 2023 at 19:30, Last updated: 24th Mar 2023 at 20:12

Views: 83, Downloads: 1

A.ALN-samples-publish2023-03-24_14-05.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Genome Alignment - Data Linked

Download

Created: 24th Mar 2023 at 20:07, Last updated: 24th Mar 2023 at 20:12

Views: 80, Downloads: 1

A.MSP-samples-publish2023-03-16_11-37.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra Analysis - Data Li...

Download

Created: 16th Mar 2023 at 17:44, Last updated: 16th Mar 2023 at 18:23

Views: 100, Downloads: 1

A.SPC-samples-publish2023-03-16_10-25.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy Analysis -...

Download

Created: 16th Mar 2023 at 17:17, Last updated: 16th Mar 2023 at 18:23

Views: 98, Downloads: 2

A.NMR-samples-publish2023-03-16_11-39.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Nuclear Magnetic Resonance Spectroscopy Analysi...

Download

Created: 16th Mar 2023 at 17:40, Last updated: 16th Mar 2023 at 18:23

Views: 100, Downloads: 0

D.PRM-samples-publish2023-03-16_11-48.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Electron Paramagnetic Resonance - Data Linked

Download

Created: 16th Mar 2023 at 17:55, Last updated: 16th Mar 2023 at 18:23

Views: 131, Downloads: 1

D.XRS-samples-publish2023-03-16_11-57.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: X-ray Photoelectron Spectroscopy - Data Linked

Download

Created: 16th Mar 2023 at 17:58, Last updated: 16th Mar 2023 at 18:23

Views: 109, Downloads: 0

D.NMR-samples-publish2023-03-16_11-23.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Nuclear Magnetic Resonance Spectroscopy - Data ..., Nuclear Magnetic Resonance Spectroscopy Analysi...

Download

Created: 16th Mar 2023 at 17:29, Last updated: 16th Mar 2023 at 18:22

Views: 83, Downloads: 1

D.MSP-samples-publish2023-03-16_11-35.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra - Data Linked, High Resolution Mass Spectra Analysis - Data Li...

Download

Created: 16th Mar 2023 at 17:43, Last updated: 16th Mar 2023 at 18:22

Views: 68, Downloads: 2

D.CRY-samples-publish2023-03-16_11-47.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Crystallography - Data Linked

Download

Created: 16th Mar 2023 at 17:54, Last updated: 16th Mar 2023 at 18:22

Views: 103, Downloads: 1

CHM-samples-publish2023-03-16_10-12.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy - Data Linked, Chemical Synthesis - Metadata, Crystallography - Data Linked, Electron Paramagnetic Resonance - Data Linked, High Resolution Mass Spectra - Data Linked, Nuclear Magnetic Resonance Spectroscopy - Data ..., X-ray Photoelectron Spectroscopy - Data Linked

Download

Created: 16th Mar 2023 at 16:20, Last updated: 16th Mar 2023 at 18:22

Views: 79, Downloads: 1

D.SPC-samples-publish2023-03-16_10-23.xlsx

MIT SRP

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy - Data Linked, Absorption and Emission Spectroscopy Analysis -...

Download

Created: 16th Mar 2023 at 17:15, Last updated: 16th Mar 2023 at 18:22

Views: 89, Downloads: 1

DNA-samples-publish2023-03-08_13-15.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

Download

Created: 8th Mar 2023 at 19:23, Last updated: 8th Mar 2023 at 23:52

Views: 104, Downloads: 0

NDMA_in-vivo_gpt_data.xlsx

MIT SRP

All creators

Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

Download

Created: 8th Mar 2023 at 19:50, Last updated: 8th Mar 2023 at 23:52

Views: 76, Downloads: 1

D.GPT-samples-publish2023-03-08_13-55.xlsx

MIT SRP

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

Download

Created: 8th Mar 2023 at 20:07, Last updated: 8th Mar 2023 at 23:52

Views: 82, Downloads: 2

Armijo-NDMA_HRMS-data.xlsx

MIT SRP

All creators

Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Mutational Spectral Analysis - Data Attached

Download

Created: 8th Mar 2023 at 23:46, Last updated: 8th Mar 2023 at 23:52

Views: 115, Downloads: 1

A.MUSP-samples-publish2023-03-08_17-46.xlsx

MIT SRP

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Mutational Spectral Analysis - Data Attached

Download

Created: 8th Mar 2023 at 23:49, Last updated: 8th Mar 2023 at 23:52

Views: 93, Downloads: 1

CEL-samples-publish2023-03-08_11-57.xlsx

MIT SRP

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 18:17, Last updated: 8th Mar 2023 at 23:52

Views: 73, Downloads: 1

TIS-samples-publish2023-03-08_12-40.xlsx

MIT SRP

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata, Necropsy - Metadata

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Created: 8th Mar 2023 at 19:11, Last updated: 8th Mar 2023 at 23:52

Views: 76, Downloads: 1

DNA-samples-publish2023-03-08_13-15.xlsx

MIT SRP

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 19:20, Last updated: 8th Mar 2023 at 23:52

Views: 60, Downloads: 0

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P.SWA-230302-V1_Jeol-Accu-ToF_05252022

MIT SRP

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Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra - Data Linked

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Created: 16th Mar 2023 at 18:16, Last updated: 16th Mar 2023 at 18:24

Views: 100, Downloads: 0

P.SWA-230223-V1_synthesis-protocol

MIT SRP

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Charles Demurjian

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Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Chemical Synthesis - Metadata

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Created: 16th Mar 2023 at 18:13, Last updated: 16th Mar 2023 at 18:23

Views: 86, Downloads: 2

P.SWA-230302-V1_Fluorescence-and-XPS

MIT SRP

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Charles Demurjian

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Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy - Data Linked, X-ray Photoelectron Spectroscopy - Data Linked

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Created: 16th Mar 2023 at 18:14, Last updated: 16th Mar 2023 at 18:23

Views: 123, Downloads: 0

P.SWA-230302-V1_Mass-Spectrometry

MIT SRP

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Charles Demurjian

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Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra - Data Linked

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Created: 16th Mar 2023 at 18:15, Last updated: 16th Mar 2023 at 18:23

Views: 108, Downloads: 1

P.SWA-230302-V1_NMR

MIT SRP

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Charles Demurjian

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Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Nuclear Magnetic Resonance Spectroscopy - Data ...

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Created: 16th Mar 2023 at 18:17, Last updated: 16th Mar 2023 at 18:23

Views: 92, Downloads: 0

P.ESS-201123-V1_gpt-NextGen-Protocol-.pdf

MIT SRP

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Charles Demurjian

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Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

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Created: 8th Mar 2023 at 20:27, Last updated: 8th Mar 2023 at 23:52

Views: 75, Downloads: 0

P.ESS-230303-V1_Data-processing-(alignment).docx

MIT SRP

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Charles Demurjian

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Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Genome Alignment - Data Linked, Mutational Spectral Analysis - Data Attached

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Created: 8th Mar 2023 at 20:32, Last updated: 8th Mar 2023 at 23:52

Views: 78, Downloads: 1

P.ESS-230303-V2_Cell-culture.docx

MIT SRP

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Charles Demurjian

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Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:28, Last updated: 8th Mar 2023 at 23:52

Views: 100, Downloads: 1

P.ESS-230308-V2_Duplex-sequencing.docx

MIT SRP

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Charles Demurjian

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Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Illumina Sequencing - Data Linked

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Created: 8th Mar 2023 at 20:30, Last updated: 8th Mar 2023 at 23:52

Views: 67, Downloads: 0

P.ENG-200831-V1_NDMA-Juvenile-Mouse-Injection-Protocol.pdf

MIT SRP

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Charles Demurjian

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Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:35, Last updated: 8th Mar 2023 at 23:52

Views: 77, Downloads: 0

P.ENG-200806-V2_Short-Term-Collection-at-Necropsy.pdf

MIT SRP

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Charles Demurjian

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Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:35, Last updated: 8th Mar 2023 at 23:52

Views: 100, Downloads: 0

P.ENG-220105-V1_NDMA-Juvenile-Mouse-Single-Injection-Protocol.docx

MIT SRP

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Charles Demurjian

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Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:36, Last updated: 8th Mar 2023 at 23:52

Views: 77, Downloads: 0

P.ENG-220105-V1_Tissue-Collection-at-Necropsy-(2021).docx

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Charles Demurjian

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Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:37, Last updated: 8th Mar 2023 at 23:52

Views: 80, Downloads: 0

P.HEM-220913-V2_20210610_fieldworkOperatingProc.docx

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Jake Schissel

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Creator: Jake Schissel

Submitter: Jake Schissel

Investigations: MIT SRP

Studies: Benthic fluxes of fluorescent dissolved organic...

Assays: Field Water Sensor Run

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Created: 11th Oct 2022 at 15:57, Last updated: 17th Oct 2022 at 21:23

Views: 231, Downloads: 4

P.HEM-220913-V2_20210520_fieldworkOperatingProc.docx

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Jake Schissel

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Submitter: Jake Schissel

Investigations: MIT SRP

Studies: Benthic fluxes of fluorescent dissolved organic...

Assays: Field Water Sensor Run

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Created: 11th Oct 2022 at 15:56, Last updated: 17th Oct 2022 at 21:23

Views: 185, Downloads: 3

P.HEM-220913-V2_20210513_fieldworkOperatingProc.docx

MIT SRP

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Jake Schissel

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Creator: Jake Schissel

Submitter: Jake Schissel

Investigations: MIT SRP

Studies: Benthic fluxes of fluorescent dissolved organic...

Assays: Field Water Sensor Run

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Created: 11th Oct 2022 at 15:55, Last updated: 17th Oct 2022 at 21:23

Views: 200, Downloads: 3

P.ESS-201123-V1_gpt-NextGen-Protocol.pdf

MIT SRP

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Dikshant Pradhan

Next-Gen GPT Assay Protocol

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: GPT Assay – Data Attached

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Created: 20th Sep 2021 at 16:24

Views: 544, Downloads: 12

P.ENG-200806-V2_Short-Term-Collection-at-Necropsy.pdf

MIT SRP

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Dikshant Pradhan

Collection of Tissues at Necropsy of Short-Term Animals

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

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Created: 20th Sep 2021 at 16:19

Views: 539, Downloads: 11

P.ENG-201008-V1_Med-Term-Collection-at-Necropsy.pdf

MIT SRP

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Dikshant Pradhan

Medium-Term Tissue Collection at Necropsy

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

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Created: 20th Sep 2021 at 16:08

Views: 576, Downloads: 10

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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

MIT SRP

Abstract

Not specified

Authors: Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward

Date Published: 1st Mar 2021

Publication Type: Journal

DOI: 10.1016/j.celrep.2021.108864

Citation: Cell Reports 34(11):108864

Created: 11th Apr 2021 at 18:33, Last updated: 8th Dec 2022 at 18:26

Views: 640, Downloads: 0