WP1: Creation of an integrated and curated cancer knowledge commons

The DrugLogics initiative comprises a number of different subprojects, all geared towards the development of personalised medicine, or precision medicine

The COLOSYS project aims to develop a deeper understanding of colon cancer networks and convert them into computer models with which it will be better to predict response to treatment. The combination of computational, experimental and clinical testing will provide understanding of drug resistance mechanisms, and allow personalised treatment of colon cancer.

A repository of causal cellular signalling statement

A guidelines for the curation of molecular interactions causal statements.

Curation guidelines for molecular interaction causal statements

Extraction of causalities from transcription and translation reactions from the Reactome pathway database.

The causal interactions service provides the extracted data of causality from Reactome database.

The Minimum Information about a Molecular Interaction Causal Statement to guide the curation of causal statements.