Colosys
OverviewThe COLOSYS project aims to develop a deeper understanding of colon cancer networks and convert them into computer models with which it will be better to predict response to treatment. The combination of computational, experimental and clinical testing will provide understanding of drug resistance mechanisms, and allow personalised treatment of colon cancer.
Programme: Druglogics
SEEK ID: https://fairdomhub.org/projects/81
Public web page: http://www.colosys.org/
Organisms: Homo sapiens
FAIRDOM PALs: No PALs for this Project
Project created: 2nd Jun 2017
Related items
Projects: CausalDB, Colosys, NTNU Health Druglogics
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-3357-425X
Projects: NTNU Health Druglogics, Colosys
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-6324-7524
Projects: Colosys
Institutions: Norwegian University of Science and Technology
The objectives of WP1 within the colosys project are:
1) Produce resources of data and information that will be used for the identification of CC driver genes (WP2) and for the construction and configuration of computational models of cancer-related biological processes (WP2 and WP3)
2) Integrate information from public patient data and cancer cell line data repositories with information from project specific clinical and model data
3) Convert information from public cellular signalling databases
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Snapshots: No snapshots
A repository of causal cellular signalling statement
Person responsible: Vasundra Toure
Snapshots: No snapshots
A guidelines for the curation of molecular interactions causal statements.
Person responsible: Vasundra Toure
Snapshots: No snapshots
Extraction of causalities from transcription and translation reactions from the Reactome pathway database.
Contributor: Vasundra Toure
Biological problem addressed: Biological Network Analysis
Snapshots: No snapshots
Curation guidelines for molecular interaction causal statements
Contributor: Vasundra Toure
Assay type: Instructions
Technology type: Technology Type
Snapshots: No snapshots
Contributor: Evert Bosdriesz
Biological problem addressed: Model Analysis Type
Snapshots: No snapshots
The causal interactions service provides the extracted data of causality from Reactome database.
Creator: Vasundra Toure
Contributor: Vasundra Toure
External Link
Log2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
DownloadLog2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
Log2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
The Minimum Information about a Molecular Interaction Causal Statement to guide the curation of causal statements.
Creator: Vasundra Toure
Contributor: Vasundra Toure
