Colosys
OverviewThe COLOSYS project aims to develop a deeper understanding of colon cancer networks and convert them into computer models with which it will be better to predict response to treatment. The combination of computational, experimental and clinical testing will provide understanding of drug resistance mechanisms, and allow personalised treatment of colon cancer.
Programme: Druglogics
SEEK ID: https://fairdomhub.org/projects/81
Public web page: http://www.colosys.org/
Organisms: Homo sapiens
FAIRDOM PALs: No PALs for this Project
Project created: 2nd Jun 2017
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Related items
Projects: CausalDB, Colosys, NTNU Health Druglogics
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-3357-425X
Projects: NTNU Health Druglogics, Colosys
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-6324-7524
Projects: Colosys, COVID-19 Disease Map
Institutions: Norwegian University of Science and Technology, Barcelona Supercomputing Center
The DrugLogics initiative comprises a number of different subprojects, all geared towards the development of personalised medicine, or precision medicine
Projects: CausalDB, Colosys, Crossover Research 2.0, NTNU Health Druglogics
Web page: http://druglogics.eu/
ROR ID: Not specified
Department: Not specified
Country: 
Germany
City: Berlin
Web page: http://www.charite.de/
ROR ID: Not specified
Department: Not specified
Country: 
Netherlands
City: Amsterdam
Web page: https://www.nki.nl/
ROR ID: Not specified
Department: Not specified
Country: 
Norway
City: Trondheim
Web page: http://www.ntnu.edu/
The objectives of WP1 within the colosys project are:
- Produce resources of data and information that will be used for the identification of CC driver genes (WP2) and for the construction and configuration of computational models of cancer-related biological processes (WP2 and WP3)
- Integrate information from public patient data and cancer cell line data repositories with information from project specific clinical and model data
- Convert information from public cellular signalling databases ...
A repository of causal cellular signalling statement
Submitter: Vasundra Toure
Investigation: WP1: Creation of an integrated and curated canc...
Assays: Causal Extraction from Reactome
A guidelines for the curation of molecular interactions causal statements.
Submitter: Vasundra Toure
Investigation: WP1: Creation of an integrated and curated canc...
Assays: MI2CAST curation guidelines
Submitter: Evert Bosdriesz
Biological problem addressed: Model Analysis Type
Investigation: 1 hidden item
Study: 1 hidden item
Curation guidelines for molecular interaction causal statements
Submitter: Vasundra Toure
Assay type: Instructions
Technology type: Technology Type
Investigation: WP1: Creation of an integrated and curated canc...
Extraction of causalities from transcription and translation reactions from the Reactome pathway database.
Submitter: Vasundra Toure
Biological problem addressed: Biological Network Analysis
Investigation: WP1: Creation of an integrated and curated canc...
The causal interactions service provides the extracted data of causality from Reactome database.
Creator: Vasundra Toure
Submitter: Vasundra Toure
External Link
Log2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
DownloadLog2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
Log2 fold changes after drug treatment/serum stimulation of MAPK and AKT pathway nodes
The Minimum Information about a Molecular Interaction Causal Statement to guide the curation of causal statements.
Creator: Vasundra Toure
Submitter: Vasundra Toure
