Heinrich Heine University of Düsseldorf

PoLiMeR is funded through the EU Marie Skłodowska-Curie Innovative Training Network (ITN), which drives scientific excellence and innovation. ITNs bring together universities, research institutes, industry and clinical partners from across the world to train researchers to doctorate level.

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease
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Collaboration with Miltos Tsiantis for reconstructing RCO transcriptional regulation

Setting up in plants UV uptogenetics for controlling the circadian clock and other pathways

improvement of PULSE, derivation of tools for ontogenetic control of interesting pathways

Modulation of light, temperature and time networks using prime editing and mathematical modelling

SMART Plants for Tomorrow’s Needs

Plants enable life on Earth through the conversion of solar energy into chemical energy. Beginning with the Neolithic Revolution, the domestication of plants provided the basis for human population growth and, subsequently, the evolution of highly developed civilizations. However, the growing food demands imposed by an increasing population and the effects of anthropogenic climate change pose huge challenges for sustainable food production and ecosystem maintenance.
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generation of a toggle switch based on a non-cooperative network

CropClock - Increasing Crops Biomass by Uncovering the Circadian Clock Network Using Dynamical Models

The circadian clock is an internal timing system that allows plants to predict daily and seasonal changes in light and temperature and thus to adapt photosynthesis, growth, and development to external conditions. The core oscillator is well understood in the model plant Arabidopsis, however, relatively little is known about the dynamic effects of the clock on agronomic behaviour of crop plants.
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