SEEK ID: https://fairdomhub.org/people/2206
Location: Germany
ORCID: https://orcid.org/0000-0003-3483-3388
Joined: 15th Jul 2022
Expertise: Not specified
Tools: Not specified
Related items
- Programmes (1)
- Projects (1)
- Institutions (1)
- Investigations (0+1)
- Studies (1)
- Assays (4)
- Data files (11+26)
- Publications (1)
- Documents (3)
Projects: SteaPKMod
Web page: https://www.uniklinikum-jena.de/avc/Forschung/Experimentelle+Chirurgie.html
Investigation regarding the impact of periportal steatosis on selected parameters of drug metabolism.
Programme: Experimental Transplantation Surgery
Public web page: https://qualiperf.de/
Organisms: Mus musculus
Submitter: Uta Dahmen
Investigation: 1 hidden item
Assays: Animal experiment and Pharmacokinetics data, Bayesian uncertainty quantification, Hematoxylin-Eosin (HE) staining, Immunohistochemistry _ CYP1A2, Immunohistochemistry _ CYP2D6, Immunohistochemistry _ CYP2E1, Immunohistochemistry _ CYP3A4, SteaPk-data Histology Quant., CYP activity, Protein, TG, AUC
Snapshots: Snapshot 1
Submitter: Mohamed Albadry
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: 1 hidden item
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Submitter: Mohamed Albadry
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: 1 hidden item
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Stained sections were digitalized using a whole slide scanner (L11600, Hamamatsu, Ja-pan) equipped with the NDP.view2Plus Image viewing software (Version U12388-02).
- MNT-021_J-20-0152_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-022_J-20-0154_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-023_J-20-0156_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-024_J-20-0158_HE_LLL(green), RML(red), RSL (black), ...
Submitter: Mohamed Albadry
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: 1 hidden item
Organisms: Mus musculus
SOPs: No SOPs
Data files: Bl6J_HE_LLL(green), RML(red), RSL (black), ICL(...
Snapshots: No snapshots
Submitter: Mohamed Albadry
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: 1 hidden item
Organisms: No organisms
SOPs: No SOPs
Data files: Bl6J_CYP3A4 1/2000_Run 10_LLL(green), RML(red),..., CYP3A4: Generic Classification 128
Snapshots: No snapshots
CYP2E1: Generic Classification 128
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2E1
- MNT-021_Bl6J_J-20-0152_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-022_Bl6J_J-20-0154_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-023_Bl6J_J-20-0156_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-024_Bl6J_J-20-0158_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-025_Bl6J_J-20-0160_CYP2E1- 1/400_Run ...
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2E1
- MNT-021_Bl6J_J-20-0152_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-022_Bl6J_J-20-0154_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-023_Bl6J_J-20-0156_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-024_Bl6J_J-20-0158_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-025_Bl6J_J-20-0160_CYP2E1- 1/400_Run ...
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2E1
- MNT-021_Bl6J_J-20-0152_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-022_Bl6J_J-20-0154_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-023_Bl6J_J-20-0156_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-024_Bl6J_J-20-0158_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-025_Bl6J_J-20-0160_CYP2D6- 1/3000_Run ...
Creators: Uta Dahmen, Mohamed Albadry
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2D6
- MNT-021_Bl6J_J-20-0152_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-022_Bl6J_J-20-0154_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-023_Bl6J_J-20-0156_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-024_Bl6J_J-20-0158_CYP2D6- 1/3000_Run 14_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_004 > Control
- MNT-025_Bl6J_J-20-0160_CYP2D6- 1/3000_Run ...
Creators: Uta Dahmen, Mohamed Albadry
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2D6
CYP1A2: Generic Classification 128
Creators: Uta Dahmen, Mohamed Albadry
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP1A2
- MNT-021_J-20-0152_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-022_J-20-0154_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-023_J-20-0156_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-024_J-20-0158_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-025_J-20-0160_Bl6J_CYP1A2-1/500_Run ...
Creators: Uta Dahmen, Mohamed Albadry
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP1A2
- MNT-021_J-20-0152_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-022_J-20-0154_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-023_J-20-0156_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-024_J-20-0158_Bl6J_CYP1A2-1/500_Run 08_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_002 > Control
- MNT-025_J-20-0160_Bl6J_CYP1A2-1/500_Run ...
Creators: Uta Dahmen, Mohamed Albadry
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP1A2
CYP3A4: Generic Classification 128
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP3A4
- MNT-021_J-20-0152_CYP3A4 1/2000_Run 10_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_005 > Control
- MNT-022_J-20-0154_CYP3A4 1/2000_Run 10_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_005 > Control
- MNT-023_J-20-0156_CYP3A4 1/2000_Run 10_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_005 > Control
- MNT-024_J-20-0158_CYP3A4 1/2000_Run 10_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_005 > Control
- MNT-025_J-20-0160_CYP3A4 1/2000_Run 10_LLL(green), RML(red), ...
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP3A4
- MNT-021_J-20-0152_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-022_J-20-0154_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-023_J-20-0156_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-024_J-20-0158_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-025_J-20-0160_HE_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_003 > Control
- MNT-026_J-20-0162_HE_LLL(green), RML(red), ...
Creators: Uta Dahmen, Mohamed Albadry
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Hematoxylin-Eosin (HE) staining
Abstract (Expand)
Authors: Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch, Uta Dahmen
Date Published: 1st Dec 2022
Publication Type: Journal
DOI: 10.1038/s41598-022-26483-6
Citation: Sci Rep 12(1),21825
steatosis pattern analysis report using Histokat, a proprietary software based on a machine-learning algorithm created by Fraunhofer MEVIS
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Hematoxylin-Eosin (HE) staining
Steatosis Quantification (Lipid droplet analysis) report using Histokat, a proprietary software based on a machine-learning algorithm created by Fraunhofer MEVIS
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Hematoxylin-Eosin (HE) staining
Excel file involves all experiment data including feeding plan, sampling plan, and the Pharmacokinetic data results
Creators: Mohamed Albadry, Uta Dahmen
Submitter: Mohamed Albadry
Investigations: 1 hidden item