SEEK ID: https://fairdomhub.org/assays/1952
Experimental assay
Projects: SteaPKMod
Investigation: hidden item
Study: Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism
Assay position: 6
Assay type: Experimental Assay Type
Technology type: Technology Type
Organisms: No organisms
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Created: 18th Jul 2022 at 14:46
Last updated: 8th Dec 2022 at 17:39
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Projects: SteaPKMod
Web page: https://www.uniklinikum-jena.de/avc/Forschung/Experimentelle+Chirurgie.html
Investigation regarding the impact of periportal steatosis on selected parameters of drug metabolism.
Programme: Experimental Transplantation Surgery
Public web page: https://qualiperf.de/
Organisms: Mus musculus
Submitter: Uta Dahmen
Investigation: 1 hidden item
Assays: Animal experiment and Pharmacokinetics data, Bayesian uncertainty quantification, Hematoxylin-Eosin (HE) staining, Immunohistochemistry _ CYP1A2, Immunohistochemistry _ CYP2D6, Immunohistochemistry _ CYP2E1, Immunohistochemistry _ CYP3A4, SteaPk-data Histology Quant., CYP activity, Protein, TG, AUC
Snapshots: Snapshot 1
CYP2E1: Generic Classification 128
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2E1
- MNT-021_Bl6J_J-20-0152_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-022_Bl6J_J-20-0154_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-023_Bl6J_J-20-0156_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-024_Bl6J_J-20-0158_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-025_Bl6J_J-20-0160_CYP2E1- 1/400_Run ...
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2E1
- MNT-021_Bl6J_J-20-0152_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-022_Bl6J_J-20-0154_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-023_Bl6J_J-20-0156_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-024_Bl6J_J-20-0158_CYP2E1- 1/400_Run 011_LLL(green), RML(red), RSL (black), ICL(yellow)_MAA_006 >Control
- MNT-025_Bl6J_J-20-0160_CYP2E1- 1/400_Run ...
Investigations: 1 hidden item
Studies: Periportal steatosis in mice affects distinct p...
Assays: Immunohistochemistry _ CYP2E1