Bayesian uncertainty quantification

The experimental data of Midazolam, OH-Midazolam, Caffein, Codeine, Norcodeine, Codein-6Glucuronide, Morphine-3Glucuronide and Morphine was analyzed via a Bayesian uncertainty quantification. An underlying model describing the bolus injection, followed by the exponential decay was written in sbml and a PEtab problem was created. The sampling and ensemble creation was conducted with the python toolbox pyPESTO.

For further details, please take a look at the methods section of the paper.


Modelling Analysis

Sebastian Höpfl

Projects: SteaPKMod

Investigation: hidden item

Study: Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism

Assay position:

Biological problem addressed: Model Analysis Type

Organisms: No organisms

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Created: 22nd Jul 2022 at 07:42

Last updated: 8th Dec 2022 at 17:39

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