Investigations

What is an Investigation?
176 Investigations visible to you, out of a total of 545

Integrated systems biology approach including transcriptome, metabolome, proteome analyses and modelling to elucidate amino acid degradation in S. solfataricus P2.

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Submitter: Beatriz García-Jiménez

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Submitter: Beatriz García-Jiménez

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Submitter: Beatriz García-Jiménez

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Submitter: Beatriz García-Jiménez

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Submitter: Beatriz García-Jiménez

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Submitter: Beatriz García-Jiménez

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Submitter: Beatriz García-Jiménez

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The objectives of WP1 within the colosys project are:

  1. Produce resources of data and information that will be used for the identification of CC driver genes (WP2) and for the construction and configuration of computational models of cancer-related biological processes (WP2 and WP3)
  2. Integrate information from public patient data and cancer cell line data repositories with information from project specific clinical and model data
  3. Convert information from public cellular signalling databases ...

Experimental data and all related material for the publication "Multi -omics reveal lifestyle of acidophile, mineral-oxidizing model species Leptospirillum ferriphilumT". changed ID

Submitter: Malte Herold

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Experimental data and all related material for the publication "Multi -omics reveal lifestyle of acidophile, mineral-oxidizing model species Leptospirillum ferriphilumT".

Gene co-epxression network analyses are common in the study of large scale biological data sets. In this study, we have developed a methodology for the comparison of pairs of co-expression networks using the s-core network peeling approach. We apply the methodology to gene-expression data for human and mouse.

The gluconeogenic conversion of 3-phosphoglycerate via 1,3-bisphosphoglycerate to glyceraldehyde-3-phosphate was compared at 30 C and at 70 C. At 30 C it was possible to produce 1,3-bisphosphoglycerate from 3-phosphoglycerate with phosphoglycerate kinase, but at 70 C, 1,3- bisphosphoglycerate was dephosphorylated rapidly to 3-phosphoglycerate, effectively turning the phosphoglycerate kinase into a futile cycle. At both temperatures it was possible to convert 3-phosphoglycerate to glyceraldehyde ...

Drug detoxification dynamics explain the postantibiotic effect

Protein abundance of AKT and ERK pathway components governs cell-type- specific regulation of proliferation

Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.

One of these activities is antibiotic production and is widespread in streptomycetes ...

Integrated systems biology approach including transcriptome, metabolome, biochemistry, proteome analyses and modelling to elucidate the catabolic pathway for L-fucose in S. solfataricus P2.

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Submitter: Maja Rey

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Submitter: Maja Rey

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