Pokhilko, Alexandra

The Centre for Engineering Biology is the University of Edinburgh's research organisation in interdisciplinary, Synthetic and Systems Biology, founded in 2023 as the successor to SynthSys, itself founded in 2012 as the successor to the Centre for Systems Biology at Edinburgh (CSBE). CSBE was newly founded in 2007. The Centre for Engineering Biology is a hub organisation that links across multiple, major funding awards, including an Engineering Biology Mission Hub, and EPSRC C-loop.

What is PlaSMo? PlaSMo stands for Plant Systems-biology Modelling Ensuring the achievements of yesterday's Mathematical Modellers will be available for the Systems Biologists of tomorrow.

Our aims

To identify plant mathematical models useful to the UK plant systems biology community, which are currently in a variety of legacy formats and in danger of being lost To represent these models in a declarative XML-based format, which is closer to the systems biology standard SBML To evaluate the behaviour ...

The first version of the model corresponds to the one published in Pokhilko et al Mol Syst Biol 2010, which is also presented on the Mol. Syst. Biol. website and was submitted to the Biomodels database. Note: minor errors in published supplementary information are documented in a file attached to version 1; the published SBML files are correct. The second version has some names slightly modified for compatibility with the SBSI platform. Both first and second versions have values of  "dawn" fixed ...

Millar lab working model, extends the Arabidopsis clock model by incorporating multiple sites of inhibition of clock gene expression by TOC1. Model is included into submitted publication "Global Mapping at the Core of the Arabidopsis Circadian Clock Defines a Novel Network Structure of the Oscillator" with Paloma Mas Version 1 has two errors corrected in version 2. This private record is now superseded by the published version, which is public as PLM_70.Originally submitted to PLaSMo on 2011-12-29 ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.

Originally submitted to PLaSMo on 2011-07-16 12:31:04

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukOriginally submitted to PLaSMo on 2011-07-16 12:31:04

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments Final model as submitted but with time changed to t for compatibilty with SBSI Originally submitted to PLaSMo on 2011-07-16 ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments Pokhilko Arabidopsis clock model as submitted, SBSI compatible and tanh light function of Kevin Stratford Originally submitted ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments Corrected version for SBSI with Kevin Stratford's tanh light function, as in the Locke tanh models. Confirmed will now run and ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments this version has a graphical representation in Cell Designer. It runs in Cell Designer, Copasi and SBSI, but not run optimization ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments this version is similar to version 5 (but csymbol time is replaced to t), it has a graphical representation in Cell Designer, ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments This version was modified from version 6 in Copasi by replacement of "light function" to L in all equations. Originally submitted ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments Alexandra's P2011 clock model with:

• skeleton photoperiod for Graf et al. PNAS 2010.

• parameter changes to simulated prr9 ...

Alexandra Pokhilko's model of the Arabidopsis clock, private drafts created in preparation for publication (Mol. Syst. Biol.), or as working versions with various modifications after publication. The published model version is also in PlaSMo as PLM_64 here.Comments Matlab files are attached to version 1 2012-01-31 11:08:51 3 amillar2 andrew.millar@ed.ac.ukVersion Comments Alexandra's P2011 model with skeleton photoperiod for Graf et al.PNAS 2010.

A Copasi file is attached. Note that another version ...

Millar lab working model, extends the Arabidopsis clock model by incorporating multiple sites of inhibition of clock gene expression by TOC1. Model is included into submitted publication "Global Mapping at the Core of the Arabidopsis Circadian Clock Defines a Novel Network Structure of the Oscillator" with Paloma Mas Version 1 has two errors corrected in version 2. This private record is now superseded by the published version, which is public as PLM_70.Version Comments The last version, which ...

Millar lab working model, extends the Arabidopsis clock model by incorporating multiple sites of inhibition of clock gene expression by TOC1. Model is included into submitted publication "Global Mapping at the Core of the Arabidopsis Circadian Clock Defines a Novel Network Structure of the Oscillator" with Paloma Mas Version 1 has two errors corrected in version 2. This private record is now superseded by the published version, which is public as PLM_70.Version Comments This is a tidied-up and ...

The first version of the model corresponds to the one published in Pokhilko et al Mol Syst Biol 2010, which is also presented on the Mol. Syst. Biol. website and was submitted to the Biomodels database. Note: minor errors in published supplementary information are documented in a file attached to version 1; the published SBML files are correct. The second version has some names slightly modified for compatibility with the SBSI platform. Both first and second versions have values of  "dawn" fixed ...

The first version of the model corresponds to the one published in Pokhilko et al Mol Syst Biol 2010, which is also presented on the Mol. Syst. Biol. website and was submitted to the Biomodels database. Note: minor errors in published supplementary information are documented in a file attached to version 1; the published SBML files are correct. The second version has some names slightly modified for compatibility with the SBSI platform. Both first and second versions have values of  "dawn" fixed ...

The first version of the model corresponds to the one published in Pokhilko et al Mol Syst Biol 2010, which is also presented on the Mol. Syst. Biol. website and was submitted to the Biomodels database. Note: minor errors in published supplementary information are documented in a file attached to version 1; the published SBML files are correct. The second version has some names slightly modified for compatibility with the SBSI platform. Both first and second versions have values of  "dawn" fixed ...

Data file for PLaSMo accesssion ID PLM_6, version 2

Data file for PLaSMo accesssion ID PLM_6, version 1

Data file for PLaSMo accesssion ID PLM_6, version 2

Data file for PLaSMo accesssion ID PLM_6, version 1

Data file for PLaSMo accesssion ID PLM_6, version 1

Originally submitted model file for PLaSMo accession ID PLM_6, version 3

Simplified model file for PLaSMo accession ID PLM_6, version 3 (use simplified if your software cannot read the file, e.g. Sloppy Cell)

Originally submitted model file for PLaSMo accession ID PLM_6, version 2

Simplified model file for PLaSMo accession ID PLM_6, version 2 (use simplified if your software cannot read the file, e.g. Sloppy Cell)

Originally submitted model file for PLaSMo accession ID PLM_6, version 1

Simplified model file for PLaSMo accession ID PLM_6, version 1 (use simplified if your software cannot read the file, e.g. Sloppy Cell)