Caulobacter crescentus Weimberg pathway

The oxidative Weimberg pathway for the five-step pentose degradation to α ketoglutarate from Caulobacter crescentus is a key route for sustainable bioconversion of lignocellulosic biomass to added-value products and biofuels. Here, we developed a novel iterative approach involving initial rate kinetics, progress curves, and enzyme cascades, with high resolution NMR analysis of intermediate dynamics, and multiple cycles of kinetic modelling analyses to construct and validate a quantitative model for the Weimberg pathway.

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Citation
Snoep, J., & Van Niekerk, D. (2020). Caulobacter crescentus Weimberg pathway. FAIRDOMHub. https://doi.org/10.15490/FAIRDOMHUB.1.INVESTIGATION.284.2
Note: This is a citation for Snapshot 2 of this Investigation, the contents of which may vary from what is shown on this page.
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Snapshot 2 (30th Jan 2020) DOI
Snapshot 1 (10th Jan 2020) DOI
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Created: 12th Mar 2019 at 13:32

Last updated: 6th Jan 2020 at 16:17

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