Figure 1H: Biphasic control can resist mutant invasion of feedback circuits.

H The arrows mark the times when a mutant with a strong activation of the sensing of y arises (for the biphasic circuit depicted in F). This mutant has a selective disadvantage and is thus eliminated.

SED-ML simulation https://jjj.bio.vu.nl/models/experiments/karin2017_fig1h/simulate

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Created: 31st Jul 2018 at 12:02

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