Figure 1D: Biphasic control can resist mutant invasion of feedback circuits.

D An arrow marks the time when a mutant with a strong activation of the sensing of y arises (for the circuit depicted in B). This mutant has a selective advantage and takes over the population.

SED-ML simulation https://jjj.bio.vu.nl/models/experiments/karin2017_fig1d/simulate

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Created: 31st Jul 2018 at 11:53

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