Investigations
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Due to its high chemical stability, the biodegradation of benzene is the most challenging amongst hydrocarbons. While oxygen-dependent oxygenases are employed by aerobic bacteria to overcome the energy barrier, the mechanism of anaerobic benzene biodegradation is still enigmatic. The sulfate-reducing, clonal enrichment culture BzS1 is capable of benzene degradation under anoxic conditions. In addition, the alkylbenzene toluene may be used as sole source of carbon and energy. In this project, the ...
Submitter: Lars Wöhlbrand
Studies: Shotgun and geLC MS/MS analysis of the solble and membrane protein-enric...
Assays: Membrane protein-enriched fraction of clonal enrichment culture BzS1 dur..., Membrane protein-enriched fraction of clonal enrichment culture BzS1 dur..., Soluble protein fraction of clonal enrichment culture BzS1 during growth..., Soluble protein fraction of clonal enrichment culture BzS1 during growth...
Collection of experiments created by Hibberd Victoria on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: cca1 lhy Long #1 CAB2 marker, cca1 lhy Long #1 CCA1 marker, cca1 lhy Long #1 CCR2 marker
Collection of experiments created by Kim, W.Y. on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: Kim et al. (2005); CO, FT; 16L:8D; WT, elf3, Kim2007 ZTL in blue light
Collection of experiments created by Sawa, M. on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Ito, S. on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: Ito 2007 wt LD PRR9 protein, Ito et al. (2008); GI, FKF1, CDF1, CO, FT; 16L:8D, 10L:14D; WT, toc1, pr...
Collection of experiments created by Niwa Y. on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: Niwa et al. (2007); GI, FKF1, CDF1, CO, FT mRNA; 10L:14D; WT, cca1;lhy, ...
Collection of experiments created by Hodge Sarah on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Nakamichi Norihito on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Matsushika A on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Song, Y.H. on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Hall A on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: The TIME FOR COFFEE Gene Maintains the Amplitude and Timing of Arabidops...
Collection of experiments created by Tsuyoshi Mizoguchi on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Helfer A on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Gould Peter on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: 12C BL-cryptochrome paper-rep1, 12C BL-cryptochrome paper-rep2, 12C BL-cryptochrome paper-rep3, 12C RBL-cryptochrome paper-rep1, 12C RBL-cryptochrome paper-rep2, 12C RBL-cryptochrome paper-rep3, 12C RL-cryptochrome paper-rep1, 12C RL-cryptochrome paper-rep2, 12C RL-cryptochrome paper-rep3, 12C RL-cryptochrome paper-rep4, 17C BL-cryptochrome paper-rep1, 17C BL-cryptochrome paper-rep2, 17C BL-cryptochrome paper-rep3, 17C RBL-cryptochrome paper-rep1, 17C RBL-cryptochrome paper-rep2, 17C RBL-cryptochrome paper-rep3, 17C RL-cryptochrome paper-rep1, 17C RL-cryptochrome paper-rep2, 17C RL-cryptochrome paper-rep3, 17C RL-cryptochrome paper-rep4, 27C BL-cryptochrome paper-rep1, 27C BL-cryptochrome paper-rep2, 27C BL-cryptochrome paper-rep3, 27C RBL-cryptochrome paper-rep1, 27C RBL-cryptochrome paper-rep2, 27C RBL-cryptochrome paper-rep3, 27C RL-cryptochrome paper-rep1, 27C RL-cryptochrome paper-rep2, 27C RL-cryptochrome paper-rep3, 27C RL-cryptochrome paper-rep4, LUC CAB CCR2 MUT BL30 2LD to 5LL 17C 05/10/11
Collection of experiments created by Kozma-Bognar Laszlo on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Thomson Adrian on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: AT0005 4x SD-3xLL, AT0006 4x LD-3xLL, AT0007 4x 03:21-LL, AT0009 4x 9:15-LL, AT0010 4x 15:9-LL, AT0011 4x 12:12-LL, AT0028: 4x 3:21-LL, AT0030: 4x 9:15-LL, AT0032: 4x15:9-LL, AT0033: 4x18:6-LL, AT0039: 6:18 then DD, AT0040: 4x 9:15-DD, AT0045: 4x15:9-DD, AT0046: 4x18:6-DD, AT0053: 4x3:21-LL, AT0055: 4x9:15-LL, AT0057: 4x12:12-LL, AT0059: 4x15:09-LL, AT0061: 4x18:6-LL, AT0062: 4x6:18-LL, AT0064: 4x3:21-LL, AT0066: 4x6:18-LL, AT0068: 4x3:21-DD, AT0070: 4x6:18-DD, AT0072: 4x9:15-DD, AT0073: 4x12:12-DD, AT0074: 4x15:9-DD, AT0075: 4x18:6-DD, AT0077: 4x3:21-DD, AT0079: 4x12:12-DD, AT0091: 4x12:12-LL
Collection of experiments created by Munoz Felipe on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished
Assays: Analysis of Control Strains Neurospora crassa, Carbon Source, Controls, Entrainment Control Analysis
Collection of experiments created by Millar Andrew on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Millar et al. (2015), TiMet double dawns, TiMet shady nights
Assays: 010514H1, 010514H2, 030413H3: 12B-12Dx4 BB3, 030714H1, 030714H2, 060213H3: 12B-12Dx4 BBx3, 060313H1: 5L15Dx4 LLx3 (T-20), 060313H2: 12F-12Dx4 FFx3, 070814H1, 070814H2, 080115H1, 080115H2, 100414H1, 100414H2, 130212H1: 5L15Dx4 LLx3 (T-20), 130213H3: 12R-12Dx4 RRx3, 130313H1: 14L14D x 4 LL x 3 (T-28), 130313H2: 12F-12Dx4 FFx3, 140515H1, 140515H2, 140814H1, 140814H2, 190614H1, 190614H2, 200213H1: 15L5D x4 LL x3 (T-20), 200213H3: 12B-12Dx4 BB3, 200313H2: 7L 21Dx4 LLx3 (T-28), 200313H3: 12L-12Dx4 LLx3, 210814H1, 210814H2, 240414H1, 240414H2, 270213H1: 10L10Dx4 LLx3 (T-20), 270213H3: 12R-12Dx4 RRx3, 270313H1: 21L 7Dx4 LLx3 (T-28), 270313H3: 12L-12Dx4 LLx3, 280814H1, 280814H2, 290313H2: 15L 5Dx4 LLx3, AT0043: 4x 12:12-DD, AT0048 4x 18:6-DD, AT0078: 4x6:18-DD, AT0080: 4x18:6-DD
Collection of experiments created by Wenden Benedicte on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Unpublished, Wenden et al. (2012)
Assays: BW-detached_LD-LL_#03, BW-detached_LD-LL_#06, BW-detached_LL-LL_#14, BW-detached_LL-LL_#16, BW-detached_LL-LL_#20, BW-intact_LD-LL_#23, BW-intact_LL-LD_#31, BW-intact_LL-LL_#37, BW-intact_LL-LL_#46, BW-intact_LL-LL_#56, BW-intact_LL-LL_#58, CCA1 and CCR2 markers in elf4 mutant under Far Red light, Clock genes under Far Red light - 3, Clock genes under Far Red light - 5, Clock genes under Far Red light - 6, Wenden_qPCR_clock_cFR, WT and elf4, Wenden_qPCR_clock_cFR, WT and phyA
Collection of experiments created by Dixon Laura on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Kieron D Edwards on the original BioDare and automatically transferred to FAIRDOM Hub.
Collection of experiments created by Chew Yin Hoon on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Chew et al. (2022)
Collection of experiments created by Flis Anna on the original BioDare and automatically transferred to FAIRDOM Hub.
Submitter: Daniel Thedie
Studies: Flis et al. (2015), Flis et al. (2016), Unpublished
Assays: Clock gene RNAs under RD-RR in clock mutants, expt 1, Clock gene RNAs under RD-RR in clock mutants, expt 2, Clock gene RNAs under RD-RR in clock mutants, expt 3, Clock gene RNAs under RD-RR in clock mutants, expt 4, Flis et al. TiMet clock gene comparison across photoperiods, McWatters A.t. Col-0 WT clock RNA timeseries, Q-PCR LD (12:12) 17C CAB2, Q-PCR LD (12:12) 17C CCA1, Q-PCR LD (12:12) 17C ELF3, Q-PCR LD (12:12) 17C ELF4, Q-PCR LD (12:12) 17C GI, Q-PCR LD (12:12) 17C LHY, Q-PCR LD (12:12) 17C LUX, Q-PCR LD (12:12) 17C PRR5, Q-PCR LD (12:12) 17C PRR7, Q-PCR LD (12:12) 17C PRR9, Q-PCR LD (12:12) 17C TOC1, TiMet WP1.1 WS seedling vs rosette, TiMet WP1.1 qRT-PCR LD to LL and LD, TiMet WP1.1 qRT-PCR elf3 LD
Isogenic cell lines neuronal activity in cureQ
Submitter: Rene Bults
Studies: MEA data analysis on Huntington, MEA data analysis on SCA1
Assays: MEA recording 1, Mea recording 3
CureQ demonstration investigation in FairdomHub
MEA data experiments test demo
These investigations reveal that Synechocystis has neither an ED pathway nor a glucose dehydrogenase/glucokinase (GHD/GK) bypass. It rather contains a promiscuous aldolase EDA that prefers KDPG as substrate but also decarboxylates oxaloacetate (OAA) and cleaves 2-keto-4-hydroxyglutarate (KHG). In addition, the synthesis of KDPG from pyruvate and GAP is catalyzed with very low efficiency.
Submitter: Jacky Snoep
Studies: Kinetic characterisation
Assays: Experimental data EDA kinetics, Mathematical model for EDA kinetic analysis
Patients subjected to extended liver resection ((e)PHx) have a high risk to experience postoperative liver dysfunction or even liver failure, especially in case of preexisting liver disease. Our research group QuaLiPerF aims to enhance the understanding of the quantitative and spatial relationship between hepatic perfusion and function in healthy, steatotic and regenerating livers after surgery using a systems medicine approach. This project will focus on assessing the impact of perfusion ...
