Shoulders Lab Individual Publications

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SEEK ID: https://fairdomhub.org/investigations/725

Projects: Shoulders Lab

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Creators and Submitter

Creator

Charles Demurjian

Submitter

Charles Demurjian

Activity

Views: 69

Created: 3rd Jun 2025 at 15:39

Last updated: 10th Jun 2025 at 15:16

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People (1)
Programmes (1)
Projects (1)
Studies (2)
Assays (8)
Data files (9)
SOPs (4)
Samples (568)

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Charles Demurjian

Projects: Hi-IMPAcTB, MIT SRP, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC), Shoulders Lab

Institutions: Massachusetts Institute of Technology

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NExtSEEK

No description specified

Projects: MIT SRP, Hi-IMPAcTB, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC), Shoulders Lab

Web page: https://nextseek.mit.edu/

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Shoulders Lab

Shoulders Lab Collagen Publications

Programme: NExtSEEK

Public web page: Not specified

Organisms: Not specified

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In vivo directed evolution of an ultrafast Rubisco from a semianaerobic environment imparts oxygen resistance

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Investigation: Shoulders Lab Individual Publications

Assays: No Assays

Snapshots: No snapshots

Created: 10th Jun 2025 at 15:44

Human cartilage model of the precocious osteoarthritis-inducing COL2A1 p.R719C reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II

Shoulders Lab

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Charles Demurjian

Kathryn M. Yammine, Sophia Mirda Abularach, Michael Xiong, Seo-yeon Kim, Agata A. Bikovtseva, Vincent L. Butty, Richard P. Schiavoni, John F. Bateman, Shireen R. Lamandé, and Matthew D. Shoulders

A dbGaP Submission is underway and metadata will be updated at the completion of submission. The remaining of the data and metadata are available here.

DOI: 10.1101/2024.11.07.622468.

Abstract:

Objectives Mutations in the procollagen-II gene (COL2A1) ...

Submitter: Charles Demurjian

Investigation: Shoulders Lab Individual Publications

Assays: Cell Imaging - Data Linked, Gene Expression Analysis - Data Linked, LC - MS/MS (Proteomics) - Data Linked, Library Creation - Metadata, Proteomics Analysis - Data Linked, RNA Extraction - Metadata, Short Read Sequencing - Data Linked, iPSC Culture and Chondronoid Formation - Metadata

Snapshots: Snapshot 1

Created: 3rd Jun 2025 at 15:41, Last updated: 9th Jun 2025 at 14:07

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iPSC Culture and Chondronoid Formation - Metadata

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_Imaging.docx, P.SHO-250605-V1_Collagen_Proteomics.docx, P.SHO-250605-V1_Collagen_RNAseq.docx, P.SHO-250605-V1_Collagen_iPSC.docx

Data files: samples-250609-SC-R719C-CEL.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:11, Last updated: 9th Jun 2025 at 15:00

Cell Imaging - Data Linked

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_Imaging.docx

Data files: TUNEL_quantification.xlsx, samples-250609-SC-R719C-CEL.xlsx, samples-250609-SC-R719C-D.IMG.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:12, Last updated: 9th Jun 2025 at 15:58

RNA Extraction - Metadata

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_RNAseq.docx

Data files: samples-250609-SC-R719C-CEL.xlsx, samples-250609-SC-R719C-RNA.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:13, Last updated: 9th Jun 2025 at 14:59

Library Creation - Metadata

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_RNAseq.docx

Data files: samples-250609-SC-R719C-DNA.xlsx, samples-250609-SC-R719C-RNA.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:14, Last updated: 9th Jun 2025 at 15:27

Short Read Sequencing - Data Linked

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_RNAseq.docx

Data files: samples-250609-SC-R719C-D.SEQ.xlsx, samples-250609-SC-R719C-DNA.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:15, Last updated: 9th Jun 2025 at 15:32

Gene Expression Analysis - Data Linked

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_RNAseq.docx

Data files: samples-250609-SC-R719C-A.GEX.xlsx, samples-250609-SC-R719C-D.SEQ.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:16, Last updated: 9th Jun 2025 at 15:39

LC - MS/MS (Proteomics) - Data Linked

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_Proteomics.docx

Data files: samples-250609-SC-R719C-CEL.xlsx, samples-250609-SC-R719C-D.MSP.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:17, Last updated: 9th Jun 2025 at 15:49

Proteomics Analysis - Data Linked

Shoulders Lab

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Charles Demurjian

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Shoulders Lab Individual Publications

Study: Human cartilage model of the precocious osteoar...

Organisms: No organisms

SOPs: P.SHO-250605-V1_Collagen_Proteomics.docx

Data files: samples-250609-SC-R719C-A.MSP.xlsx, samples-250609-SC-R719C-D.MSP.xlsx

Snapshots: No snapshots

Created: 9th Jun 2025 at 14:20, Last updated: 9th Jun 2025 at 15:56

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TUNEL_quantification.xlsx

Shoulders Lab

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Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Cell Imaging - Data Linked

Download

Created: 9th Jun 2025 at 15:58

samples-250609-SC-R719C-A.MSP.xlsx

Shoulders Lab

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Proteomics Analysis - Data Linked

Download

Created: 9th Jun 2025 at 15:51

samples-250609-SC-R719C-D.MSP.xlsx

Shoulders Lab

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: LC - MS/MS (Proteomics) - Data Linked, Proteomics Analysis - Data Linked

Download

Created: 9th Jun 2025 at 15:46

samples-250609-SC-R719C-A.GEX.xlsx

Shoulders Lab

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Gene Expression Analysis - Data Linked

Download

Created: 9th Jun 2025 at 15:35

samples-250609-SC-R719C-D.SEQ.xlsx

Shoulders Lab

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Gene Expression Analysis - Data Linked, Short Read Sequencing - Data Linked

Download

Created: 9th Jun 2025 at 15:19

samples-250609-SC-R719C-DNA.xlsx

Shoulders Lab

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Library Creation - Metadata, Short Read Sequencing - Data Linked

Download

Created: 9th Jun 2025 at 15:12

samples-250609-SC-R719C-D.IMG.xlsx

Shoulders Lab

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Cell Imaging - Data Linked

Download

Created: 9th Jun 2025 at 15:04

samples-250609-SC-R719C-RNA.xlsx

Shoulders Lab

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Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Library Creation - Metadata, RNA Extraction - Metadata

Download

Created: 9th Jun 2025 at 14:58

samples-250609-SC-R719C-CEL.xlsx

Shoulders Lab

All creators

Charles Demurjian

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Cell Imaging - Data Linked, LC - MS/MS (Proteomics) - Data Linked, RNA Extraction - Metadata, iPSC Culture and Chondronoid Formation - Metadata

Download

Created: 9th Jun 2025 at 14:46

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P.SHO-250605-V1_Collagen_Proteomics.docx

Shoulders Lab

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Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: LC - MS/MS (Proteomics) - Data Linked, Proteomics Analysis - Data Linked, iPSC Culture and Chondronoid Formation - Metadata

Download

Created: 9th Jun 2025 at 14:30

P.SHO-250605-V1_Collagen_Imaging.docx

Shoulders Lab

All creators

Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Cell Imaging - Data Linked, iPSC Culture and Chondronoid Formation - Metadata

Download

Created: 9th Jun 2025 at 14:27

P.SHO-250605-V1_Collagen_RNAseq.docx

Shoulders Lab

All creators

Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: Gene Expression Analysis - Data Linked, Library Creation - Metadata, RNA Extraction - Metadata, Short Read Sequencing - Data Linked, iPSC Culture and Chondronoid Formation - Metadata

Download

Created: 9th Jun 2025 at 14:25

P.SHO-250605-V1_Collagen_iPSC.docx

Shoulders Lab

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Charles Demurjian

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: Shoulders Lab Individual Publications

Studies: Human cartilage model of the precocious osteoar...

Assays: iPSC Culture and Chondronoid Formation - Metadata

Download

Created: 9th Jun 2025 at 14:23

Showing 20 out of a possible 568 Samples Advanced Samples list for this Investigation with search and filtering

A.MSP-250606SHO-1

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:56

A.MSP-250606SHO-2

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:56

A.MSP-250606SHO-3

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:56

D.MSP-250606SHO-1

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:49

D.MSP-250606SHO-2

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:49

A.GEX-250605SHO-1

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:39

A.GEX-250605SHO-2

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:39

D.SEQ-250605SHO-1

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-2

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-3

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-4

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-5

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-6

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-7

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-8

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-9

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-10

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-11

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-12

Shoulders Lab

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Charles Demurjian

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Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

D.SEQ-250605SHO-13

Shoulders Lab

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Charles Demurjian

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Creators: None

Submitter: Charles Demurjian

Created: 9th Jun 2025 at 15:32

View all 568 Samples