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Created: 22nd Jul 2025 at 09:14
Last updated: 29th Sep 2025 at 12:24

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Projects: Group Data Science, Group Microbial Interface Biology, Core Facility Fluorescence Cytometry, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis, Methylation differences during respiratory infection, Lipid droplet formation and dynamics in murine macrophages, Implementation of Nanopore Sequencing for Detection of Treatment Induced Transcriptomic and Epitranscriptomic Changes in Leukaemic Tumour Models, Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae, OMICS of vascular smooth muscle cells under oxidative stress, Lung health related PGS and GWAS, Archaean stimulation of human primary PBMCs and PBMCs monocytes
Institutions: Forschungszentrum Borstel

Expertise: Bioinformatics, Genomics, Transcriptomics
Projects: Group Data Science, Group Microbial Interface Biology, Core Facility Fluorescence Cytometry, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis, Methylation differences during respiratory infection, Lipid droplet formation and dynamics in murine macrophages, OMICS of vascular smooth muscle cells under oxidative stress, Lung health related PGS and GWAS, Archaean stimulation of human primary PBMCs and PBMCs monocytes
Web page: https://fz-borstel.de
Organisms: Not specified
Illumina RNA Sequencing of human PBMCs of 9 donors stimulated with two archaea, measured after 4 and 24 hours as well as without stimulation after 24 hours as control
Submitter: Inken Wohlers
Studies: Differential expression, Transcriptome profiling
Assays: Comparison of all conditions, Expression profiling with heatmaps and PCA
Snapshots: No snapshots
This compares the five conditions Control at 24 hours, Methanobrevibacter smithii (MBS) at 4 and 24 hours, Methanosphaera stadtmanae (MSS) at 4 and 24 hours in a joint model. The respective conditions are abbreviated Control_24h, MBS_4h, MBS_24h, MSS_4h, MSS_24h
Submitter: Inken Wohlers
Biological problem addressed: Model Analysis Type
Investigation: Illumina RNA sequencing of archaean stimulated ...
Study: Differential expression
Organisms: No organisms
Models: No Models
SOPs: No SOPs
Data files: Main workflow results as HTML report, Quality report using MultiQC, Workflow results: plots, Workflow results: tables
Snapshots: No snapshots
Creator: Inken Wohlers
Submitter: Inken Wohlers
Investigations: Illumina RNA sequencing of archaean stimulated ...
Studies: Differential expression
Assays: Comparison of all conditions
Creator: Inken Wohlers
Submitter: Inken Wohlers
Investigations: Illumina RNA sequencing of archaean stimulated ...
Studies: Differential expression
Assays: Comparison of all conditions
Creator: Inken Wohlers
Submitter: Inken Wohlers
Investigations: Illumina RNA sequencing of archaean stimulated ...
Studies: Differential expression
Assays: Comparison of all conditions
Creator: Inken Wohlers
Submitter: Inken Wohlers
Investigations: Illumina RNA sequencing of archaean stimulated ...
Studies: Differential expression
Assays: Comparison of all conditions