SEEK ID: https://fairdomhub.org/studies/1348
Projects: OMICS of vascular smooth muscle cells under oxidative stress
Study position:
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Creators and SubmitterViews: 11
Created: 12th Feb 2025 at 11:36
Last updated: 19th Dec 2025 at 13:01
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Projects: Group Data Science, Methylation differences during respiratory infection, Implementation of Nanopore Sequencing for Detection of Treatment Induced Transcriptomic and Epitranscriptomic Changes in Leukaemic Tumour Models, OMICS of vascular smooth muscle cells under oxidative stress, Systems genetics of lung health and asthma (GWAS, PGS, QTL)
Institutions: Forschungszentrum Borstel
The FZB is the lung research center of the Leibniz Association and is therefore committed to the motto “theoria cum praxi”.
The FZB sees its scientific and socio-political task in basic, disease- and patient-oriented lung research and training in this field. The field of research includes chronic inflammatory diseases of the lung of infectious and non-infectious environmental and behavioral origin. Research focuses on tuberculosis, infections with non-tuberculous mycobacteria and other bacterial ...
Projects: Group Data Science, Group Microbial Interface Biology, Core Facility Fluorescence Cytometry, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis, Methylation differences during respiratory infection, Lipid droplet formation and dynamics in murine macrophages, OMICS of vascular smooth muscle cells under oxidative stress, Systems genetics of lung health and asthma (GWAS, PGS, QTL), Archaean stimulation of human primary PBMCs and PBMCs monocytes
Web page: https://fz-borstel.de
Programme: Research Center Borstel
Public web page: Not specified
Organisms: Not specified
Submitter: Ayat Ismail
Studies: Differential transcript expression analysis, RNA modification detection
Assays: Comprehensive RNA Modification Analysis and Visualization, Differential gene expression and pathway enrichment using Deseq2
Snapshots: No snapshots
Submitter: Ayat Ismail
Biological problem addressed: Model Analysis Type
Investigation: ONT direct RNA Sequencing
Organisms: No organisms
Models: No Models
SOPs: No SOPs
Data files: All figures in PDF form, C3 vs Others – DESeq2 reproducible conda workflow, DESeq2 condition based analysis, DESeq2_DE_Transcript_Lists.csv, DiffExp and pathway enrichment report.pdf, Input files
Snapshots: No snapshots
Creator: Ayat Ismail
Submitter: Ayat Ismail
Investigations: ONT direct RNA Sequencing
Creator: Ayat Ismail
Submitter: Ayat Ismail
Investigations: ONT direct RNA Sequencing
Conda-based DESeq2 pipeline (R 4.5 + Bioconductor) that renders a Quarto report comparing C3 samples to all others in two commands. Bundle includes DET.yml, DET.sh, and DE_C3_vs_all.qmd
Creator: Ayat Ismail
Submitter: Ayat Ismail
Investigations: ONT direct RNA Sequencing
This Quarto Markdown file performs differential gene expression analysis using DESeq2, followed by pathway enrichment analysis for Gene Ontology (GO) and KEGG pathways. It includes a heatmap of the top differentially expressed genes and results for GO and KEGG pathway analysis, providing insights into the biological processes affected by experimental conditions.
Creator: Ayat Ismail
Submitter: Ayat Ismail
Investigations: ONT direct RNA Sequencing
Creator: Ayat Ismail
Submitter: Ayat Ismail
Investigations: ONT direct RNA Sequencing
Creator: Ayat Ismail
Submitter: Ayat Ismail
Investigations: ONT direct RNA Sequencing
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