People

I am a PhD student of the microbiology department at the Ludwig-Maximilians Universität München. I work at the chair of Prof. Kirsten Jung. The topic of our workpackage deals with "K+ homeostasis in Escherichia coli". In special I'm working on the sensor kinase KdpD that controls together with the response regulator KdpE the expression of the high-affinity K+ uptake system KdpFABC. The yet not fully understood molecular mechanism of stimulus perception and signal transduction is of particular
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I am performing research in biomarkers discovery, particularly regarding liver fibrosis in non-alcoholic fatty liver disease. My research activities involved the use of bioinformatic platforms, the analysis of biological protein-protein interaction networks and the experimental validation of candidates by ELISA.

General Bioinformatics

Professor of Computer Science University of Manchester
Co-Director of the FAIRDOM Initiative and co-leader of the SEEK4Science Platform Development
Deputy Head of Node ELIXIR-UK
Co-lead ELIXIR Interoperability Backbone Platform
Lead ISBE WP Data and Model Management
Data lead SynBioChem Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals

Data management and standardization expert for systems biology and systems medicine, responsible for the data management user requirements and user contacts within the German LiSyM network (Liver Systems Medicine: http://lisym.org/) and associated to the FAIRDOM team.
Involved in different standardization initiatives and committees, i.e. COMBINE (http://co.mbine.org), ISO/TC 276 Biotechnology (https://www.iso.org/committee/4514241.html), European COST action CHARME (http://www.cost-charme.eu) and
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Professor in Jinan University, Guangzhou, China.
My research interest is in the modeling of translation. Connecting various processes in translation, we can investigate the impact of different factors on protein biosynthesis and biogenesis in genome-wide scale. This may reveal various general mechanisms on control level of gene expression and folding efficiency regulation in different growth conditions.

Post-doctoral research associate working in Sheffield in the SUMO consortium.

The major theme of the research in my laboratory is bacterial gene regulation. We are interested in signal perception mechanisms (in particular oxygen); signal transduction (ligand induced protein confromational changes); interaction of transcription factors with the core transcription machinery; interactions between transcription factors to integrate multiple signals; and the influence of promoter architectures on these events. We are also interested in aome aspects of post-transcriptional
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Hi, this is Caroline from Creative Biomart, a world leading biotech company that specialized in providing protein, recombinant protein, cell lines, and GMP proteins.
visit http://www.creativebiomart.net/ to see more details.

POSITION
Professor of Systems Medicine/Biology at the Academic Medical Center, Amsterdam and University Medical Center Groningen, Groningen, The Netherlands

RESEARCH
My major projects focus on understanding the etiology of metabolic syndrome and its comorbidities type2 diabetes and cardiovascular disease. To get grip on the sequence of events in disease progression we make use of longitidunal models and apply multiscal systems biology approaches.

PUBLICATIONS

My published work can be found at:
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s.f.groothuis@umcg.nl

Process engineer, modeling biological systems since 1985.