Winogradsky Institute of Microbiology, Federal Research Center “Biotechnology", Russian Academy of Sciences
I am a Deputy Director of Vinogradsky Institute of Microbiology, Russian Academy of Sciences, Moscow, Russia and the head of the laboratory in this Institute. I ams working in the field of diversity, ecology and metabolism of thermophilic prokaryotes. Together with colleagues we've described many new taxa of thermophilic prokaryotes including those of high level (families, orders, levels). I m especially interested in isolation and description of thermophilic prokaryotes with unusual types of
Background- Thermophilic organisms are composed of both bacterial and archaeal species. The enzymes isolated from these species and from other extreme habitats are more robust to temperature, organic solvents and proteolysis. They often have unique substrate specificities and originate from novel metabolic pathways. Thermophiles as well as their stable enzymes (‘thermozymes’) are receiving increased attention for biotechnological applications.
The proposed project will establish thermophilic in
The aim of the project is bioprospecting, isolation and characterization of novel secondary metabolites, produced by extremophilic microorganisms. The project is dedicated to a poorly investigated problem of antagonistic interactions between extremophilic microorganisms in their communities, namely, to the investigation of the ability of extremophiles to produce secondary metabolites with biocidic, cytotoxic and cytostatic activities. Working out this problem will fulfill an important applied
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