Projects: Group Data Science, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis
Institutions: Forschungszentrum Borstel
https://orcid.org/0009-0008-0344-2740Expertise: Bioinformatics, Data analysis, Proteomics, Python, R
Projects: MESI-STRAT
Institutions: Charité University Medicine Berlin
https://orcid.org/0000-0001-5440-5503Tools: R, Python, Data Science, Bioinformatics, Single Cell analysis
PhD student
Projects: DigiSal, GenoSysFat, SEEK tutorial for DigiSal
Institutions: Norwegian University of Life Sciences
https://orcid.org/0000-0002-7450-619XExpertise: Computational Systems Biology, Bioinformatics, Data analysis
Researcher at the DigiSal project. Recently graduated M.Sc. in Chemistry and Biotechnology.
Projects: GenoSysFat, DigiSal, SEEK tutorial for DigiSal, PhD Nicotinic Acetylcholine Receptors
Institutions: Norwegian University of Life Sciences
https://orcid.org/0000-0003-0089-0608Expertise: Molecular Biology, Cell biology, transcriptional regulation, Genetics, Microbiology
Tools: R, Cell and tissue culture, PCR, Latex, Genetic analysis
Ph.D. student at the Norwegian University of Life Sciences interested in protein stoichiometry and genetics. Currently, I am studying nicotinic acetylcholine receptors in salmon lice, in an effort to understand how they function, their stoichimetric structure and their importance to the salmon louse. This is part of a larger fundamental research project which covers several invertebrates including bees, mosquitos and ticks, as ...
Expertise: Bioinformatics, Computational Systems Biology, Data Management, Databases, Python, R, Transcriptomics, Image analysis, Genomics, Molecular Biology, Microbiology, Data analysis, Genetics
Tools: qPCR, Isolation purification and separation, Genomics, Data Science, RNA / DNA Techniques, Transcriptomics, Microbiology, Molecular Biology, Databases
I am a biochemist & bio-informatician working in phytobacteriology at the Plant Sciences Unit of ILVO, the Flanders Research Institute for Agricultural, Fisheries and Food Research. The focus is on genomics-based research and diagnostics for Plant Health.
My expertise is 'wet-lab' work (microbiology, sequencing, molecular biology, design & validation of diagnostics assays using qPCR/LAMP, automatisation) and 'dry-lab' work such as bio-informatics/data analysis (e.g. scripting analysis ...
Expertise: drought, plant ecophysiology, quantitative genetics, plant growth, models, phenotyping
Tools: sensors, high throughput phenotyping, imaging, R
Projects: MPIEvolBio-SciComp
Institutions: Max Planck Institute for Evolutionary Biology
https://orcid.org/0000-0002-2579-5546I'm heading the Scientific Computing Unit at Max Planck Institute for Evolutionary Biology in Plön, Germany. My interest is the application of high performance and high throughput computing in data processing, data analysis, and numerical simulations of dynamical processes. I have a background in Theoretical Physics with a Ph.D. from Rostock University (2008), where I studied analytical models and numerical simulations of extremely dense and hot matter.
After a postdoc at the Lawrence Livermore ...
Projects: COVID-19 Disease Map
Institutions: University Maastricht
https://orcid.org/0000-0002-7770-620XExpertise: Knowledge integration, Curation, Data Integration, rare diseases, Systems Biology, GMP, GCP, Neuroscience
Tools: wikipathways, pathvisio, Cytoscape, R, Python, Statistics
Projects: EmPowerPutida, COVID-19 Disease Map
Institutions: Wageningen University & Research, University Maastricht
https://orcid.org/0000-0003-3091-3962Expertise: Systems Biology, Mathematical modelling, Biotechnology, Synthetic Biology, Metabolic Engineering, metabolism, Metabolic Networks, SARS-CoV 2, COVID-19, Pathway Curation, Pathway Analysis, Network Analysis
Tools: Matlab, Computational Systems Biology, Flux balance analysis, omics analysis, Python, R, Constraint-based analysis
My research interest is in studying cellular and molecular pathways of COVID-19 disease.
Projects: COVID-19 Disease Map
Institutions: Monash University
https://orcid.org/0000-0002-9207-0385Expertise: Bioinformatics, Machine Learning, Data analysis, Deep Learning, Molecular Biology, Plant biology
Tools: Python, R, SQL, High Performance Computing
Projects: COVID-19 Disease Map
Institutions: Pondicherry University
https://orcid.org/0000-0003-4854-8238Expertise: Bioinformatics, Transcriptomics, Computational Systems Biology, Data analysis
Tools: Data Integration, R, Databases, Python, Cytoscape, network theory
PhD Student at Centre for Bioinformatics, Pondicherry University, Pondicherry, India.
Projects: COVID-19 Disease Map, Covid-19 Interferon pathway modelling and analysis
Institutions: University of Nebraska-Lincoln
https://orcid.org/0000-0001-7528-3568Expertise: Computational modelling, Data analysis, Data Integration
Tools: R, Matlab, Cell designer, Cell Collective, Cytoscape
Projects: COVID-19 Disease Map
Institutions: independent researcher
https://orcid.org/0000-0002-3882-6073Expertise: Data analysis, Bioinformatics, Molecular Biology, Genetics, Neuroscience
Tools: Data Science, R, Cell designer, SBML, Single Cell analysis, Transcriptomics
Projects: COVID-19 Disease Map
Institutions: Fundación Progreso y Salud
https://orcid.org/0000-0003-2632-9587Projects: Not specified
Institutions: Not specified
Expertise: Deep Learning
Tools: R, Python, Shell scripting
Projects: COVID-19 Disease Map
Institutions: European Molecular Biology Laboratory
https://orcid.org/0000-0002-7249-9379Expertise: protein-protein interactions, Databases, Pathways, lipidomics, Data analysis, Visualization
Projects: COVID-19 Disease Map
Institutions: MRC-University of Glasgow Centre for Virus Research
https://orcid.org/0000-0003-0411-4497Expertise: Modeling, Bioinformatics, Systems Biology
Tools: R
Bioinformatician / Computational Biologist
Projects: CoolWine
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-3485-1634Expertise: Systems Biology
Tools: network theory, FBA, R, Python, Statistics
PhD candidate working on the CoolWine project
Projects: COVID-19 Disease Map
Institutions: University of Cape Town
https://orcid.org/0000-0002-5374-0657Expertise: Genomics, Data analysis
Projects: COVID-19 Disease Map, Covid-19 Interferon pathway modelling and analysis, Boolean modeling of Parkinson disease map
Institutions: Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg
https://orcid.org/0000-0001-7403-181XExpertise: Machine Learning, Deep Learning, Modeling, Medical microbiology, Molecular Biology
Tools: Python, R, Matlab, Javascript, SBML, Dynamic modelling, microbiology techniques, Shell scripting
Projects: COVID-19 Disease Map
Institutions: European Institute for Systems Biology and Medicine
https://orcid.org/0000-0002-2108-7657Expertise: Network Analysis, Modelling
Projects: COVID-19 Disease Map
Institutions: BIOASTER
Projects: COVID-19 Disease Map
Institutions: National Institute for Infectious Diseases "L.Spallanzani"
https://orcid.org/0000-0001-8076-7217Expertise: Network Analysis, Modelling
Tools: R, RNAseq, network theory, Genomics
Projects: COVID-19 Disease Map
Institutions: University of Pittsburgh
Expertise: Mathematical modelling, Network Analysis, Dynamics and Control of Biological Networks
Tools: R, Matlab, Python, ODE Modelling
Projects: COVID-19 Disease Map
Institutions: Barcelona Supercomputing Center
https://orcid.org/0000-0002-7696-1241I completed my BSc in Biology and MSc in Cell Biology by the University of Valencia. During my last undergrad year I participated in synthetic biology’s iGEM competition where I dove in the use of models in Biology, which pushed me to pursue a PhD in the Department of Applied Mathematics in the Technical University of Valencia.
My research on Metabolic Engineering of hydrogen in cyanobacteria led me to be visiting researcher at Uppsala University, Denmark Technical University and EMBL Heidelberg. ...
Expertise: Biochemistry, Cell biology, Data analysis, Dynamic modelling, Systems Biology, Image analysis, Genetics, Molecular Biology, R, SBML, Curation, Quantitative Biology, Physical Chemistry
Tools: Biochemistry and protein analysis, Bioinformatics, Systems Biology, SBML, R, ODE, Molecular biology techniques (RNA/DNA/Protein), Genetics, Dynamic modelling, Computational and theoretical biology, CellDesigner, Parameter estimation
Tools: Systems Biology, R
Projects: GMDS Project Group "FAIRe Dateninfrastrukturen für die Biomedizinische Informatik"
Institutions: University Medical Center Göttingen
https://orcid.org/0000-0002-6307-3253Expertise: Data Management, Databases, Health Informatics, Data Integration
Tools: R, Docker, linux, Data Management
Researcher at the University Medical Center Göttingen, Department of Medical Informatics
Projects: pISA-tree, HYp - Spatiotemporal analysis of hypersensitive response to Potato virus Y in potato, INDIE - Biotechnological production of sustainable indole, _p_stRT, ADAPT - Accelerated Development of multiple-stress tolerAnt PoTato, tst, tst2
Institutions: National Institute of Biology, tst
https://orcid.org/0000-0002-1669-6482Expertise: Molecular Biology, Statistics, Bioinformatics, Mathematical and statistical modeling, Programming, Data analysisMathematical modellingBioinformaticsSystems biology, Data Management, Data analysis, Visualization, Data Integration, Computational Biology
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Molecular Biology, Python, R, Systems Biology, Data Integration
Computational Biologist and Biostatistician at Department of Biotechnology and Systems Biology, National Institute of Biology (NIB)
Projects: iRhythmics, OLCIR: Optimization of Lung Cancer Therapy with Ionizing Radiation
Institutions: University of Rostock
https://orcid.org/0000-0002-1887-4772Expertise: Bioinformatics, Transcriptomics, RNA-Seq, AI, Data Integration
Projects: WG Infrastructure for Translational Research, GMDS Project Group "FAIRe Dateninfrastrukturen für die Biomedizinische Informatik", Translational Bioinformatics, Medical Biometry, Epidemiology, Medical Informatics
Institutions: University Medical Center Göttingen, University of Tübingen, University of Saarland
https://orcid.org/0000-0002-1505-594XExpertise: Programming, Bioinformatics, Data Management, Databases, Java, Python, R, standards, Data Integration
Tools: Python, Bioinformatics, Data Management, Databases, R, Java, Data Integration
PhD in Biotechnology, Research Associate at Department of Biotechnology and Systems Biology, National Institute of Biology
Projects: FAIRDOM user meeting
Institutions: Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI)
Expertise: Bioinformatics, Data Management, Python, R, Databases, RNA-Seq, secondary metabolites, gene clusters, Perl
Projects: PHYTOCAL: Phytochrome Control of Resource Allocation and Growth in Arabidopsis and in Brassicaceae crops, Light and plant development, Light control of leaf development
Institutions: University of Edinburgh
https://orcid.org/0000-0003-0737-2408Expertise: arabidopsis thaliana, caenorhabditis elegans, circadian rhythms, chronobiology, Transcriptomics, splicing, alternative splicing, R, photobiology, plant architecture, leaf development
Tools: Molecular Biology, Molecular biology techniques (RNA/DNA/Protein), R, Systems Biology, Transcriptomics, Bioinformatics, Databases, Genetics, Plant biology, C. elegans biology
Projects: DigiSal, GenoSysFat, SAFE-Aqua, Unlock
Institutions: Wageningen University & Research
https://orcid.org/0000-0001-8172-8981Expertise: semantics, Software Engineering, R, Python, Java, Data Management, Databases, Genetics, Genomics, Microbiology
Projects: MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, DigiSal, WURSynBio, INDIE - Biotechnological production of sustainable indole
Institutions: Wageningen University & Research
https://orcid.org/0000-0001-5845-146XExpertise: Metabolic modelling, Systems Biology, Transcriptomics, R, SBML
Associate Professor at Wageningen University & Research
Projects: Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW), EraCoBiotech 2 nd call proposal preparation, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation
Institutions: VU University Amsterdam, Universitat Rovira i Virgili
https://orcid.org/0000-0001-9103-9127Expertise: PBPK modeling, Pharmacology, Pharmacokinetics, Mechanistic Modelling
Tools: R, Berkeley Madonna, Copasi, Cell designer
Projects: EmPowerPutida
Institutions: LifeGlimmer GmbH
Expertise: Bioinformatics, Systems Biology, Transcriptomics, R, Genomics, Proteomics, Databases, Data Integration
Tools: Bioinformatics, Molecular Biology, Computational Systems Biology
Computational Biologist and App Designer @LifeGlimmer
Projects: MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, WURSynBio
Institutions: Wageningen University & Research
https://orcid.org/0000-0001-7049-5334Expertise: Bioinformatics, Systems Biology, Agent-based modelling, Dynamic modelling, Python, Java, R, pathogen host interaction, Molecular Biology
Tools: Copasi, libRoadrunner, Python, R, semantic web
I am a researcher (PhD student) working at Wageningen University & Research as bioinformatician and modeller. I am working as part of the MycoSynVac (http://www.mycosynvac.eu/) project on dynamic modelling of central carbon metabolism in M. pneumoniae, to be extended to full dynamic modelling of metabolism to be implemented in a whole cell model. I am also looking into possibilities to improve standards in model generation using semantic technologies, improving automatic generation, annotation ...
Projects: SBEpo - Systems Biology of Erythropoietin
Institutions: German Cancer Research Center (DKFZ)
https://orcid.org/0000-0002-0971-2309Expertise: Mathematical modelling, Single Cell analysis, Cell biology, Molecular Biology
Tools: Biochemistry, Systems Biology, Matlab, R
Expertise: Bioinformatics, Molecular Biology, Next Generation Sequencing, metagenomics, Proteomics, Programming
Tools: bash, Perl, R, Genomics, Proteomics, Biochemistry and protein analysis
Research scientist in multi-Omics, molecular (cell)biology and bioinformatics.
Projects: HYp - Spatiotemporal analysis of hypersensitive response to Potato virus Y in potato, pISA-tree, INDIE - Biotechnological production of sustainable indole, _p_stRT, Public project, Playground, SUSPHIRE - Sustainable Bioproduction of Pheromones for Insect Pest Control in Agriculture
Institutions: National Institute of Biology, NewHorizon
https://orcid.org/0000-0001-7484-6031Postdoctoral researcher at Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Projects: HUMET Startup, EraCoBiotech 2 nd call proposal preparation, COVID-19 Disease Map
Institutions: geneXplain GmbH
https://orcid.org/0000-0001-6775-2467Expertise: Systems Biology, promoters and anhancers, gene regulation, signal transduction, drug targets
Tools: geneXplain platform, BioUML, R, c++
Alexander Kel received his Ph.D. in Bioinformatics, Molecular Biology and Genetics in 1990. He studied biology and mathematics at Novosibirsk State University and obtained his M.S. in biology with special focus on mathematical biology in 1985. He worked for 15 years at the Institute of Cytology and Genetics, Russia (ICG) holding positions as a programmer, scientist, senior scientist and Vice-Head of the Laboratory of Theoretical Molecular Genetics. In 1995, he won the Academician Belaev Award. ...
Projects: HUMET Startup, COVID-19 Disease Map
Institutions: Centro de Investigación Príncipe Felipe, Fundación Progreso y Salud
https://orcid.org/0000-0003-3318-120XExpertise: Bioinformatics, Data Management, Mathematical modelling, Genomics, Genetics, Transcriptomics, Systems Biology, Microarray analysis, Data Integration
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Genetics, Genomics, R, Systems Biology, Transcriptomics, Java
My scientific interests revolve around functional genomics, systems biology and the development of algorithms and software for the analysis of high-throughput data (mainly, but not restricted to, Next Generation Sequencing) and its application to the relationship between genotype and phenotype, mainly oriented to personalized and precision medicine. I am especially interested in the study of disease mechanisms and drug action mechanisms, drug repositioning and the definition of mechanism-based ...
Projects: FAIRDOM user meeting
Institutions: SYSBIO - Centre of Systems Biology
https://orcid.org/0000-0002-6566-2844Expertise: Bioinformatics, Data Management, Databases, Microarray analysis, Systems Biology
Projects: FAIRDOM user meeting
Institutions: Peter MacCallum Cancer Centre
Expertise: Systems Biology, Transcriptomics, Genomics
Tools: Systems Biology, Transcriptomics, Computational Systems Biology, Bioinformatics, R
Projects: SulfoSys - Biotec
Institutions: University Bielefeld
Expertise: Bioinformatics, Data Management, Transcriptomics, Proteomics, Metabolomics, Databases, Data Integration
Tools: Bioinformatics, Data Management, Databases, R, Java
Projects: SilicoTryp, SYSTERACT, SynBio4Flav
Institutions: University of Glasgow, Chalmers University of Technology
https://orcid.org/0000-0002-3593-5792Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: University of Tokyo
Expertise: Genetics, Genomics, Cell biology, Image analysis, Phenome, Genetic interaction
Tools: Fluorescence microscopy, CalMorph, R, Java, GLM, Model selection
I am a postdoc in The University of Tokyo. My research interest is to know structure of biological systems by functional relationships between genes working in response to endogenous and/or exogenous disruptions. I'm trying to find functional relationships between genes by similarity of phenotype defined with high-dimensional morphological features in yeast gene deletion collection. I'm happy if you will talk with me in any topics.
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Universität Konstanz
Expertise: Molecular Biology, Systems Biology, Mathematical modelling
Tools: quantitative western blot analysis, Molecular Biology, Java, octave, R, ODE
I studied Life Science (which is similar to chemical biology) at the University of Konstanz and became interested in Bioinformatics, Systems Biology and quantitative analyses during my Master's. In my PhD project I combine experimental analyses with modeling and parameter estimation approaches to quantitatively analyse regulation of apoptosis at the level of the Bcl-2 protein family.
Projects: MOSES
Institutions: Medical University Vienna
Expertise: Bioinformatics
Tools: Data Management, Computational and theoretical biology, Transcriptomics, Perl, Microarray analysis, R, PHP, SQL
General Bioinformatics
Projects: TRANSLUCENT
Institutions: University of Applied Sciences Koblenz, Rhein Ahr Campus
Expertise: Ma
Tools: Computational and theoretical biology, Matlab, R, Biophysics, Thermodynamics, Machine Learning
I am working in the mathematical modeling of potassium homeostasis. In addition, we are developing tools and methods for the statistical analysis of biological data.
Projects: SUMO
Institutions: University of Stuttgart
I'm interested in the application and development of methods of systems theory in biology (systems biology). In particulary I work on the following topics: Thermodynamic constraints on biochemical network; Model reduction; Modeling and Analysis of metabolic regulation.
Projects: TRANSLUCENT
Institutions: University of Applied Sciences Koblenz, Rhein Ahr Campus
Grammar school until 1998 1998-99 Alternative civilian service 1999-2002 Professional education as male nurse 2002-2007 Study of Biomathematics 2007-... PhD student in TRANSLUCENT project
Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
Institutions: University of Tuebingen, University of Tübingen
Projects: TRANSLUCENT
Institutions: Humboldt-Universität zu Berlin
Assay: _A_03.2_components Short Name: 03.2_components Assay Class: DRY Assay Type: components Title: Components: tr2aacds headers, cdhit-2d Description: Components: tr2aacds headers, cdhit-2d; post-filtering redefinition of paralogue clusters pISA Assay creation date: 2019-10-22 pISA Assay creator: Ziva Ramsak Phenodata: None Featuredata: Data:
Submitter: Maja Zagorscak
Biological problem addressed: Annotation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /intermediate_4_cdhit-2d.tar.gz, /output/output.tar, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_03.1_filtering Short Name: 03.1_filtering Assay Class: DRY Assay Type: filtering Title: Filtering according to biological evidence; removal of contaminants, chimeras and suspicious constructs Description: Filtering according to biological evidence; removal of contaminants, chimeras and suspicious constructs pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: No organisms
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /intermediate/intermediate.tar, /output/Desiree_tr.cds.tsv.gz, /output/PW363_tr.cds.tsv.gz, /output/Rywal_tr.cds.tsv.gz, /output/other/output_full.tar.gz, /output/other/output_summary.tar.gz, /reports/03.1_Rywal_combo_withFiltering.html, /reports/03.2_PW363_combo_withFiltering.html, /reports/03.3_Desiree_combo_withFiltering.html, /reports/SupplementaryTableS3, /reports/SupplementaryTableS4, /reports/SupplementaryTableS5, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_02.3_InterProScan Short Name: 02.3_InterProScan Assay Class: DRY Assay Type: InterProScan Title: InterProScan on tr2aacds output Description: InterProScan on tr2aacds output pISA Assay creation date: 2019-10-22 pISA Assay creator: Marko Petek Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Annotation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /intermediate/intermediate.tar, /output/Desiree_IPS_filtered_aggregated_filtere..., /output/PW363_IPS_filtered_aggregated_filtered.tsv, /output/Rywal_IPS_filtered_aggregated_filtered.tsv, /reports/IPS_PowerQuery_PivotTable.xlsx, /scripts/01_potato_tr_evigene_IPS_commands.txt, /scripts/02_reshape_merge_aggregate_filter.Rmd
Snapshots: Snapshot 1
How to connect to the FAIRDOM SEEK with the collection of their APIs.
Creators: None
Submitter: Andrej Blejec
The FEM models how metabolic slowdown will induce the age-related changes of weight gain, insulin resistance, basal inflammation, mitochondrial dysfunction, as well as the age-related disease of atherosclerosis, via a series of unavoidable homeostatic shifts.
Creators: James Wordsworth, Pernille Yde Nielsen
Submitter: James Wordsworth
Model type: Ordinary differential equations (ODE)
Model format: R package
Environment: Not specified
Organism: Not specified
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: Marko Petek, Maja Zagorščak, Andrej Blejec, Živa Ramšak, Anna Coll, Špela Baebler, Kristina Gruden
Date Published: 21st Nov 2021
Publication Type: Journal
DOI: 10.1101/2021.11.18.468977
Citation: biorxiv;2021.11.18.468977v2,[Preprint]
Abstract (Expand)
Authors: Marko Petek, Maja Zagorščak, Živa Ramšak, Sheri Sanders, Elizabeth Tseng, Mohamed Zouine, Anna Coll, Kristina Gruden
Date Published: No date defined
Publication Type: Not specified
DOI: 10.1101/845818
Citation: Cultivar-specific transcriptome and pan-transcriptome reconstruction of tetraploid potato