Francesco Messina
SEEK ID: https://fairdomhub.org/people/1592
Location:
Italy
ORCID:
https://orcid.org/0000-0001-8076-7217
Joined: 18th Apr 2020
Expertise: Network Analysis, Modelling
Tools: R, RNAseq, network theory, Genomics
Their tagsRelated items
The Disease Maps Project is designed as a large-scale community effort. It is a network of groups that work together in order to better understand disease mechanisms. The project exchanges best practices, share information, develop tools to make it easier for all the involved groups to achieve their goals.
Projects: COVID-19 Disease Map
Web page: https://disease-maps.org
Here we share resources and best practices to develop a disease map for COVID-19. The project is progressing as a broad community-driven effort. We aim to establish a knowledge repository on virus-host interaction mechanisms specific to the SARS-CoV-2. The COVID-19 Disease Map is an assembly of molecular interaction diagrams established based on literature evidence.
Programme: Disease Maps
Public web page: http://doi.org/10.17881/covid19-disease-map
An exploration on gene expression data was carried out on single-cell RNAseq analyses of bronchoalveolar lavages from nine COVID-19 patients, three moderate cases, one severe case and five critical cases (GSE145826) (doi: 10.1038/s41591-020-0901-9). To these data, single-cell RNA-sequencing from one COVID-19 lung biopsy, ~10 weeks after initial infection was added to represent persistent severe COVID19 patient group (3 weeks after symptom onset) (GSE163919). For this analysis, the epithelial cell ...
TGF beta signalling
Creator: Francesco Messina
Submitter: Marek Ostaszewski
Model type: Graphical model
Model format: SBML
Environment: Not specified
External LinkInteractions of the SARS-CoV-2 E protein with human proteins in the context of histone acetylation.
Creator: Francesco Messina
Submitter: Marek Ostaszewski
Model type: Not specified
Model format: Not specified
Environment: Not specified
