Projects: Simulation Foundries, CML for thermophysical properties of mixtures, Test Project (dummy), Towards Reproducible Enzyme Modeling
Institutions: University of Stuttgart, Karlsruhe Institute of Technology (KIT)
https://orcid.org/0000-0001-9119-1778Expertise: enzyme kinetics, enzymes, Enzymatic reactions, biochemical enzyme characterization, Biochemistry, molecular simulation, molecular modeling, Programming, Bioinformatics, Computational Biology
Tools: Gromacs, Python, Molecular Dynamics, bash, Biochemistry, Bioinformatics, Biochemistry and protein analysis, Enzyme assay, enzyme kinetics, isothermal titration calorimetry, dynamic light scattering, Spectrophotometry
Polyglot European Scientist. I thrive working in interdisciplinary environments combining the study of enzyme reactions and mechanisms with bioinformatics, molecular modelling, automated data analysis and data stewardship.
Expertise: Bioinformatics, Biochemistry, Data Management
Tools: Bioinformatics, Data Management, Biochemistry and protein analysis
Data Steward for the Plant Biology and Breeding Division of INRAe (https://www.inrae.fr/en/divisions/bap)
Expertise: Biochemistry, Cell biology, Data analysis, Dynamic modelling, Systems Biology, Image analysis, Genetics, Molecular Biology, R, SBML, Curation, Quantitative Biology, Physical Chemistry
Tools: Biochemistry and protein analysis, Bioinformatics, Systems Biology, SBML, R, ODE, Molecular biology techniques (RNA/DNA/Protein), Genetics, Dynamic modelling, Computational and theoretical biology, CellDesigner, Parameter estimation
Projects: HOTSOLUTE
Institutions: Consiglio Nazionale delle Ricerche
https://orcid.org/0000-0002-3399-7973Projects: Not specified
Institutions: Not specified
Projects: HOTSOLUTE
Institutions: University Duisburg-Essen
Expertise: Protein and Enzyme structure and mechanism, Thermophilic proteins in industrial biocatalysis, Biochemistry, Bioinformatics, Microbiology, Molecular Biology, Proteomics
Tools: Biochemistry, Biochemistry and protein analysis, Bioinformatics, Microbiology, Molecular biology techniques (RNA/DNA/Protein), Proteomics
I'm currently a Postdoc at the Institute of Technical Biochemistry in Stuttgart University. My project involves the experimental validation of the Indirect Enzymatic Dehydration Via Phosphorylation and Dephosphorylation of Isobutanol for Isobutene production.
I am performing research in biomarkers discovery, particularly regarding liver fibrosis in non-alcoholic fatty liver disease. My research activities involved the use of bioinformatic platforms, the analysis of biological protein-protein interaction networks and the experimental validation of candidates by ELISA.
Projects: OXYMOD
Institutions: Norwegian University of Science and Technology
Projects: OXYMOD
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-1644-3223Expertise: protein NMR, lytic polysaccharide monooxygenases
Tools: NMR, Molecular Biology, Biochemistry and protein analysis, Python
Projects: OXYMOD
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0003-1613-4663Assist. Prof. of Enzyme Technology Laboratory, Department of Chemistry, University of Crete, Greece
Expertise: Biochemical analysis, protein extraction, protein purification, ELISA, Immunoblots, Immunoassays, oral food challenge, Data analysis, Mass spectrometry (LC-MS/MS), food allergy, peanut and treenut allergy, Molecular Biology, Microbiology
Tools: Biochemistry and protein analysis, molecular biology techniques, 1D and 2D SDSPAGE, immunoblot, ELISA Techniques, Immunological techniques, oral food challenge matrix preparation for food allergy research, data analysis and data management, Mass spectrometry, protein purification, food allergen characterisation
Projects: BioZEment 2.0, BESTER, Auromega, C1Pro, AquaHealth (ERA-BlueBio)
Institutions: SINTEF
Projects: WURSynBio, INDIE - Biotechnological production of sustainable indole
Institutions: Wageningen University & Research
Projects: SysMetEx
Institutions: University Duisburg-Essen
Expertise: Bioinformatics, Molecular Biology, Next Generation Sequencing, metagenomics, Proteomics, Programming
Tools: bash, Perl, R, Genomics, Proteomics, Biochemistry and protein analysis
Research scientist in multi-Omics, molecular (cell)biology and bioinformatics.
Projects: SYSTERACT
Institutions: University of Tübingen
Expertise: Microbiology, Molecular Biology, Genetics, Transcriptomics, Metabolic Engineering, nitrogen metabolism, Streptomyces coelicolor, Actinobacteria, antibiotic production
Tools: Fermentation, Genetic modification, Molecular biology techniques (RNA/DNA/Protein), Proteomics, Transcriptomics, Biochemistry and protein analysis
Projects: MetApp, INBioPharm, SYSTERACT, Auromega
Institutions: SINTEF
https://orcid.org/0000-0002-1221-8598Research scientist
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: University of Milano-Bicocca
I am a PostDoc working on yeast metabolomics. During my PhD I studied the interplay between metabolism, cell cycle and signalling, mainly focusing on the Snf1/AMPK pathway. I am currently interested in studying metabolic rewiring caused by different nutrients, generating high-throughput data suitable for modelling.
Projects: SysMO-LAB
Institutions: University of Amsterdam
Expertise: carbon metabolism, Biochemistry, Fermentation, Glycolysis, Microbiology
Tools: Chromatography, Fermentation, Biochemistry and protein analysis
Projects: MOSES, ExtremoPharm, ZucAt, GenoSysFat, DigiSal, EraCoBiotech 2 nd call proposal preparation, FAIRDOM & LiSyM & de.NBI Data Structuring Training
Institutions: University of Stuttgart, University of Hohenheim, Norwegian University of Life Sciences, Norwegian University of Science and Technology
https://orcid.org/0000-0002-7973-9902Expertise: Biochemistry, coupling metabolome and environome, rapid sampling experiments, Systems Biology, carbon metabolism, Stoichiometric modelling, Proteomics, Metabolomics, yeast, fungi, Dynamics and Control of Biological Networks
Tools: Biochemistry and protein analysis, Metabolomics, Matlab, Fermentation, Chromatography, Material balance based modeling, stimulus response experiments, continuous cultivation, Enzyme assay, Mass spectrometry (LC-MS/MS), HPLC, GC and LC/MS analysis of metabolites, ODE, Parameter estimation
I've become a SysMO DB PAL for MOSES project in 2007 being a post-doc in lab of Prof. Matthias Reuss at University of Stuttgart. In the MOSES project, our major efforts were in the experimental data acquisition for dynamic model of primary carbon and anaerobic energy metabolism in yeast. The model implements prediction of perturbations of two types: glucose pulse and temperature jump. We implement “stimulus-response” methodology for the unraveling the dynamic structure of the network and to ...
Projects: MOSES
Institutions: VU University Amsterdam
Projects: TRANSLUCENT
Institutions: Institute of Physiology Academy of Sciences
Expertise: Microbiology, Biochemistry, Molecular Biology
Tools: Biochemistry and protein analysis, mutant strain generation, Fluorecence based reporter gene analyses/single cell analyses, molecular biological techniques (RNA/DNA techniques analyses of transport across cell membranes heterologous expression of transporters
biochemistry, molecular biology and physiology of lower eukaryotes, characterization of cell membrane transporters
Projects: KOSMOBAC
Institutions: University of Aberdeen
I am a research technician at the Institute of Medical Science in Aberdeen, working for Prof. Ian Booth. The topic of our workpackage deals with K+ homostasis in Escherichia coli. I am working with the protein KefF, a regulatory subunit of the potassium channel KefC.
Projects: KOSMOBAC
Institutions: Max-Planck-Institute of Biochemistry Martinsried
I am a PhD student working the group of Zoya Ignatova. Cellular and extracellular changes like crowding and osmotic stress conditions play a major role in protein aggregation. A change in the cytoplasmic composition is the result of an interplay between high osmotic pressures outside the cell volume and the cellular response to it in terms of uptake of K+ and secondary organic osmolytes. My research focuses on elucidating the role of natural osmolytes (known also as chemical chaperones or compatible ...
Projects: COSMIC
Institutions: Wageningen University & Research
Expertise: Microbiology, Molecular Biology
Tools: Biochemistry and protein analysis, Genomics, Transcriptomics, Metabolomics, Fermentation
I am assistant professor at the Laboratory of Microbiology and my interest is in the area of molecular microbiology. Research focuses on the analysis of the metabolism of anaerobic fermentative bacteria and archaea, especially with respect to biofuel production (hydrogen, butanol). Within SysMo our tasks concern the effect of butanol stress, using metabolomics and transcriptomics.
Projects: KOSMOBAC
Institutions: Max-Planck-Institute of Biochemistry Martinsried
Expertise: Biochemistry, Molecular Biology, translational control of gene expression, translatome, folding pathways
Tools: Biochemistry and protein analysis, Spectroscopy and structural analysis, rtPCR, fluorescence spectroscopy, quantitative western blot analysis, Molecular biology techniques (RNA/DNA), Fluorescence and confocal microscopy FRAP/FLIP
The focus of our research is the protein biogenesis and how stress-related factors modulate it. Protein biogenesis in general comprises various processes, i.e., translation, protein folding, each of which responds differently to external stress stimuli. Using systems biology approaches we seek to understand the interplay between these processes in fine-tuning the protein pattern and proteins’ abundance under osmotic stress conditions.
Projects: KOSMOBAC
Institutions: Max-Planck-Institute of Biochemistry Martinsried
Expertise: Microbiology, Biochemistry, Molecular Biology, Bioinformatics, Mathematical modelling, sequencing
Tools: Microbiology, Molecular Biology, Bioinformatics, Biochemistry and protein analysis, Matlab, Fermentation, rtPCR, molecular biological techniques (RNA/DNA techniques, qPCR, Transcriptomics
Professor in Jinan University, Guangzhou, China. My research interest is in the modeling of translation. Connecting various processes in translation, we can investigate the impact of different factors on protein biosynthesis and biogenesis in genome-wide scale. This may reveal various general mechanisms on control level of gene expression and folding efficiency regulation in different growth conditions.
Projects: BaCell-SysMO
Institutions: University of Goettingen
Expertise: Microbiology, Genetics, Molecular Biology, Bacillus subtilis, regulation of gene expression, protein-protein interactions, Mycoplasma pneumoniae, Cell physiology, protein-RNA interactions
Tools: Microbiology, Molecular Biology, Biochemistry and protein analysis, Genetic analysis, Genetic modification, Proteomics (2D-PAGE), mutant strain generation, Chemical cross-linking, SubtiWiki, SPINE, bacterial two-hybrid system
Projects: SUMO
Institutions: University of Sheffield
The major theme of the research in my laboratory is bacterial gene regulation. We are interested in signal perception mechanisms (in particular oxygen); signal transduction (ligand induced protein confromational changes); interaction of transcription factors with the core transcription machinery; interactions between transcription factors to integrate multiple signals; and the influence of promoter architectures on these events. We are also interested in aome aspects of post-transcriptional ...
Projects: BaCell-SysMO
Institutions: University of Greifswald
Expertise: Microbiology, Molecular Biology, Bacillus subtilis, stress responses, functional protein expression, carbon metabolism
Tools: Molecular Biology, Biochemistry and protein analysis, Proteomics, Proteomics (2D-PAGE), 2-D Gel Electrphoresis, GeLC-MS/MS, metabolic labeling, absolute quantification, AQUA
I'm Post-Doc in the lab of Prof. Becher at the University of Greifswald. I'm working on the relative and absolute protein quantitation using gel-based and mass-spectrometric methods.
Projects: BaCell-SysMO
Institutions: University of Newcastle
Expertise: Microbiology, Molecular Biology, Gram positive bacteria (Bacillus, Systems Biology, Genetics)
Tools: Microbiology, Molecular Biology, Biochemistry and protein analysis, Cell biology, Genetic analysis, Genomics, Transcriptomics, Proteomics, Model organisms, Proteomics (2D-PAGE), gene regulation, DNA technology RNA technology Protein analysis Fermentation Mutagenesis, molecular biological techniques (RNA/DNA techniques), protein interaction studies
Optimisation of Bacillus subtilis for the secretion of heterologous proteins Therapeutic proteins (including those required for experimental purposes and clinical trials) are major products of biomanufacturing processes and considerable time and expense are expended to maximise the yield and quality of proteins produced in heterologous hosts. The production host of choice is the Gram-negative bacterium Escherichia coli for which many strains and expression systems have been developed. However, ...
Projects: KOSMOBAC
Institutions: Ludwig-Maximilians University of Munich
Expertise: Microbiology, Biochemistry, Genetics, Molecular Biology
Tools: Genetics, Biochemistry and protein analysis, Fermentation, Chromatography, Membrane protein biochemistry, molecular biological techniques (RNA/DNA techniques), spectroscopy, site-directed and random mutagenesis, plasmon resonance spectroscopy, reporter gene analyses
I am a PhD student of the microbiology department at the Ludwig-Maximilians Universität München. I work at the chair of Prof. Kirsten Jung. The topic of our workpackage deals with "K+ homeostasis in Escherichia coli". In special I'm working on the sensor kinase KdpD that controls together with the response regulator KdpE the expression of the high-affinity K+ uptake system KdpFABC. The yet not fully understood molecular mechanism of stimulus perception and signal transduction is of particular ...
Projects: SUMO
Institutions: University of Sheffield
Expertise: Escherichia coli, Microbiology Biochemistry Molecular biology Genetics Enzymology Synthetic biology Regulatory metabolic networks, Bacterial Cell Biology, Cellular biology of metals
Tools: Biochemistry and protein analysis, Transcriptomics, Spectroscopy and structural analysis, molecular biological techniques (RNA/DNA techniques
Work in my laboratory is focussed on microbial physiology - the study of how bacteria and other microorganisms work. Although rooted in the tradition of bacterial growth and intermediary metabolism, microbial physiology now embraces molecular biology, genetics, biochemistry, and indeed any discipline that can shed light on bacterial function. Much of our experimental work is conducted with Escherichia coli, the pre-eminent ‘model’ organism with unrivalled ease of genetic and physiological ...
Projects: BaCell-SysMO
Institutions: University of Erlangen-Nuernberg
Expertise: Bacillus subtilis, functional protein expression, bacterial metabolism, carbon metabolism, Bacterial Cell Biology, Protein-DNA-interaction, Microbiology/ Protein chemistry/ Molecular Biology, Cell physiology, regulation of gene expression, quantative biology
Tools: Microbiology, Biochemistry and protein analysis, Cell biology, Model organisms, Chromatography, Molecular biology techniques (RNA/DNA/Protein), DNA, surface plasmon resonance spectroscopy, reporter gene analysis
Projects: SulfoSys, SulfoSys - Biotec
Institutions: University of Sheffield
I am the foundation Professor of Systems Biology and Engineering within the Department of Chemical and Process Engineering (CPE), at The University of Sheffield. My research philosophy is centred on a mechanistic systems biology approach to solve biochemical reaction engineered processes. I wish to pursue issues involved in the effective utilisation of biological resources. The approach is specifically targeted at the conjunction of chemical engineering (metabolic engineering and synthetic biology), ...
Projects: SulfoSys
Institutions: Wageningen University & Research
Expertise: Microbiology, Biochemistry, Molecular Biology
Tools: Biochemistry and protein analysis, Fermentation, Microarray analysis
I obtained my PhD in 1989 at the Free University (Amsterdam) on a research project in which microbial physiology, biochemistry, and molecular biology were combined. Subsequently I spent 3 years abroad, 2.5 years of which as EMBO fellow at the EMBL (Heidelberg, Germany) where I worked on protein engineering and protein crystallization. I returned to Amsterdam as KNAW fellow for 3 years, during which I worked on protein analysis and pathway engineering. In 1995 I was appointed as group leader ...
Projects: SilicoTryp
Institutions: University of Heidelberg
Expertise: Biochemistry
Tools: Biochemistry and protein analysis, enzyme kinetics, RNA interference
Professor of Biochemistry at the Centre of Biochemistry of Heidelberg University, teaching biochemistry for medical and biology students Research focus is the trypanothione redox metabolism of African trypanosomes (Trypanosoma brucei). The work is funded within the Collaborative Research Centre 544 on "Control of Tropical Infectious Diseases" of the German Research Foundation
Projects: SysMO-LAB
Institutions: University of Rostock
Expertise: Molecular microbiology
Tools: Biochemistry and protein analysis, Genetic modification, Metabolomics
Projects: SysMO-LAB
Institutions: University of Rostock
Expertise: Microbiology, Molecular microbiology
Projects: SilicoTryp
Institutions: University of Heidelberg
Expertise: Biochemistry