Institutions: UNIBI: Bielefeld Universityhttps://orcid.org/0000-0002-6100-9135
Projects: HUMET Startup
Institutions: Université catholique de Louvainhttps://orcid.org/0000-0003-2040-2448
Tools: Genetic modification, Glucose metabolism, LPS measurments, Microbiology, Lipid metabolism, Gut microbiota analysis, Animal models, Integrative physiology, Molecular biology techniques (RNA/DNA/Protein)
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research and group leader in the Metabolism and Nutrition lab at the Louvain Drug Research Institute from the UCL, Brussels, Belgium. He is WELBIO investigator and recipient of an ERC Starting Grant 2013 and a PoC ERC Grant 2016. He is laureate of the Baillet-Latour grant for medical research and the international prize of Physiology Lucien Dautrebande. His main research interests are the investigation of interactions
I started to work with B. subtilis during my diploma thesis in Marburg, analyzing the gene expression pattern during sporulation and their control by the four sporulation sigma factors. This work was continued during my PhD thesis in Greifswald. In collaboration with Prof. Bremer and Prof. Marahiel in Marburg we also studied additional adaptation processes of B. subtilis, like the adaptation to low temperatur and high osmolarity.
I am now working as a staff scientist in Prof. Völkers lab in
I'm an 'experimentalist' (molecular microbiologist) Postdoc working on regulation and peptide signaling in Clostridium acetobutylicum.
I'm also a SysMO-DB PAL (Product Application Liason) for COSMIC, working on data management including standards and integration with SysMO SEEK.
Expertise: Systems Biology, regulation of gene expression, Signal transduction in Gram-negative bacteria; Synthetic Microbiology; Single cell gene expression; Regulatory networks; biochemistry; histidine ki..., gene regulation, stress responses, bistability, sporulation, phenotypic heterogeneity, translational control of gene expression, Bacillus subtilis, Molecular Biology, Genetics, Microbiology
Tools: Time-lapse fluorescence microscopy Flow cytometry, time lapse microscopy, Molecular biology techniques (RNA/DNA), Fluorecence based reporter gene analyses/single cell analyses, PCR, Model organisms, Single Cell analysis, Genetic modification, Genetic analysis, Molecular Biology, Genetics, Microbiology
A molecular microbiologist with a passion for Clostridia! Interested in the development of more effective countermeasures (diagnosis, prevention & treatment) against pathogens, specifically Clostridium difficile and Clostridium botulinum as well as the exploitation of the medical and industrial properties of beneficial strains, specifically in cancer therapy and biofuel production
Tools: SubtiWiki, SPINE, bacterial two-hybrid system, Chemical cross-linking, Proteomics (2D-PAGE), mutant strain generation, Genetic analysis, Genetic modification, Biochemistry and protein analysis, Molecular Biology, Microbiology
Projects: PSYSMO, DigiSal, GenoSysFat, HUMET Startup, EmPowerPutida, MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, SAFE-Aqua, INDIE - Biotechnological production of sustainable indole
Roles: Project Coordinator
Tools: metabolic netwlrk visualization, reverse engineering, computational platform development, microbiology techniques, Metabolic Engineering, Computational Systems Biology, Microarray analysis, Fermentation, Proteomics, Genetic modification, Bioinformatics
My research activities has been to use mathematical models and Computational Biology to answer biological questions, intertwining in silico and experimental methods at all stages. I have a strong interest in exploring the interfaces between Fundamental Biology and bona fide Engineering, specifically in the realm of environmental and industrial problems. The research goals of my group are to contribute to the elucidation of mechanisms underlying basic cellular processes, evolution and ecological
Roles: Project Coordinator
Expertise: genetic engineering, Streptomyces, Protein-DNA-interaction, Microarray experiments with prokaryotes, Molecular microbiology, bacterial gene regulation, regulation of gene expression, Transcriptomics, Microbiology
Tools: transcription analysis, analysis of functional genomics data, microbiology techniques, reporter gene analyses, site-directed and random mutagenesis, Mutant and Strain Construction, Molecular biology techniques (RNA/DNA/Protein), Bioconductor Packages in R, Northern analyses), Chip-chip, Microarray analysis, PCR, Transcriptomics, Genetic modification, Microbiology
Expertise: overflow metabolism in Bacillus, mRNA, carbon catabolite regulation in Gram positive bacteria, Clostridium, carbon metabolism, regulation of gene expression, Bacillus subtilis, Molecular Biology, Microbiology
Tools: microbiology techniques, Western blot analyses, reporter gene analyses, qRT-PCR, absolute quantification, Optimal experimental design, Molecular biology techniques (RNA/DNA), northern blot analysis, cultivation, Genetic modification
Roles: Project Coordinator
The Veening lab is interested in phenotypic bi-stability in Streptococcus pneumoniae and its importance in virulence of this human pathogen.
Expertise: fluorescence protein fusions (transcriptional and translational), localisation studies, microscopy, protein secretion, functional protein expression, gene regulation, stress responses, phenotypic heterogeneity, Bacillus subtilis, Microarray analysis, Molecular Biology, Genetics
Tools: DNA affinity chromatography, EMSA, Molecular biology techniques (RNA/DNA/Protein), transposon mutagenesis, Immunofluorescence, Fluorescence microscopy, Flow cytometry, Site-directed mutagenesis, Fluorecence based reporter gene analyses/single cell analyses, Microarray analysis, Transcriptomics, Genetic modification
PhD student. Analyzing CcpA affinity to cre boxes (catabolite responsive elements) and response of B. subtilis to membrane protein overproduction stress.