SEEK ID: https://fairdomhub.org/people/180
Location: Spain
ORCID: Not specified
Joined: 28th Oct 2009
Expertise: Microbiology, Transcriptomics, regulation of gene expression, bacterial gene regulation, Molecular microbiology, Microarray experiments with prokaryotes, Protein-DNA-interaction, Streptomyces, genetic engineering
Tools: Microbiology, Genetic modification, Transcriptomics, PCR, Microarray analysis, Chip-chip, Northern analyses), Bioconductor Packages in R, Molecular biology techniques (RNA/DNA/Protein), Mutant and Strain Construction, site-directed and random mutagenesis, reporter gene analyses, microbiology techniques, analysis of functional genomics data, transcription analysis
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- Programmes (1)
- Projects (1)
- Institutions (1)
- Investigations (1)
- Studies (1)
- Data files (1)
- Publications (4)
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Global metabolic switching in Streptomyces coelicolor
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
Programme: SysMO
Public web page: Not specified
Organisms: Streptomyces coelicolor
All creators
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
One of these activities is antibiotic production and is widespread in streptomycetes ...
Submitter: Jay Moore
Studies: ScoCyc metabolic pathway curation, Timeseries 1
Assays: Metabolic pathway curation, Online/offline measurements, metabolomics, proteomics, transcriptomics
Snapshots: No snapshots
All creators
Genotype: Wildtype (M145E) Medium: Phosphate-limited (F134)
Submitter: Jay Moore
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Assays: Online/offline measurements, metabolomics, proteomics, transcriptomics
Snapshots: No snapshots
All creators
Creators: David Rand, R Jansen, Maria Elena Merlo, Morris Swertz, Preben Krabben, Kay Nieselt, Wolfgang Wohlleben, Jens Reuther, David Hodgson, Anthony Palathingal, David Wild, Elizabeth Wellington, Gregory Challis, Nigel Burroughs, Walid Omara, William Gaze, Brent Kiernan, Roxane Legaie, Sunniva Hoel, Juan-Francisco Martin, Antonio Rodríguez-García, Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Jay Moore, Alexander Wentzel, Maggie Smith, Louise Thomas, Eriko Takano, Lubbert Dijkhuizen, Rainer Breitling, M. Tauqeer Alam
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST...
Studies: Timeseries 1
Assays: transcriptomics
All authors
Abstract (Expand)
Authors: , Florian Battke, Alexander Herbig, , , , , , , , , Edward R Morrissey, Miguel A Juarez-Hermosillo, , Merle Nentwich, , Mudassar Iqbal, , , , , , , , Michael Bonin, , , , , , , , , ,
Date Published: 28th May 2009
Publication Type: Not specified
PubMed ID: 20053288
Citation:
Abstract (Expand)
Authors: , Alberto Sola-Landa, Kristian Apel, Fernando Santos-Beneit,
Date Published: 24th Mar 2009
Publication Type: Not specified
PubMed ID: 19321498
Citation:
Abstract (Expand)
Authors: Fernando Santos-Beneit, , Alberto Sola-Landa,
Date Published: 11th Feb 2009
Publication Type: Not specified
PubMed ID: 19220751
Citation:
Abstract (Expand)
Authors: Fernando Santos-Beneit, , Etelvina Franco-Domínguez,
Date Published: 1st Aug 2008
Publication Type: Not specified
PubMed ID: 18667568
Citation: