SEEK ID: https://fairdomhub.org/studies/56
Metabolism of Streptomyces coelicolor (SysMO STREAM)
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Experimentalists: David Hodgson
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Created: 4th Nov 2010 at 14:30
Last updated: 2nd Nov 2016 at 08:38
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Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
Projects: INBioPharm, SYSTERACT, BESTER, OXYMOD
Institutions: SINTEF
Projects: STREAM, SYSTERACT, INBioPharm, BioZEment 2.0, OXYMOD, BESTER, AquaHealth (ERA-BlueBio)
Institutions: SINTEF
https://orcid.org/0000-0002-9420-1959The main objective of the ERANET proposal Systems Biology Applications - ERASysAPP (app = application = translational systems biology) is to promote multidimensional and complementary European systems biology projects, programmes and research initiatives on a number of selected research topics. Inter alia, ERASysAPP will initiate, execute and monitor a number of joint transnational calls on systems biology research projects with a particular focus on applications - or in other words so called ...
Projects: SysVirDrug, SysMilk, SysMetEx, MetApp, IMOMESIC, WineSys, CropClock, SYSTERACT, XyloCut, RootBook, ROBUSTYEAST, LEANPROT, ErasysApp Funders
Web page: https://www.cobiotech.eu/about-cobiotech/erasysapp
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
There is an urgent need for novel antibiotics to fight life-threatening infections and to counteract the increasing problem of propagating antibiotic resistance. Recently, new molecular genetic and biochemical tools have provided insight into the enormous unexploited genetic pool of environmental microbial biodiversity for new antibiotic compounds. New tools for more efficiently lifting this hidden treasure are needed to strengthen competitiveness of European industry, as well as for a cost-saving ...
Programme: ERASysAPP
Public web page: https://www.erasysapp.eu/calls/2nd-call/systeract
Organisms: Streptomyces coelicolor
Global metabolic switching in Streptomyces coelicolor
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
Programme: SysMO
Public web page: Not specified
Organisms: Streptomyces coelicolor
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Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
One of these activities is antibiotic production and is widespread in streptomycetes ...
Submitter: Jay Moore
Studies: ScoCyc metabolic pathway curation, Timeseries 1
Assays: Metabolic pathway curation, Online/offline measurements, metabolomics, proteomics, transcriptomics
Snapshots: No snapshots
Submitter: Jay Moore
Biological problem addressed: Metabolic Network
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Organisms: Streptomyces coelicolor : M145 (wild-type / wild-type)
Models: 1 hidden item
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots