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SEEK ID: https://fairdomhub.org/studies/56
Metabolism of Streptomyces coelicolor (SysMO STREAM)
Experimentalists: David Hodgson
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Created: 4th Nov 2010 at 15:30
Last updated: 2nd Nov 2016 at 09:38
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Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
Projects: INBioPharm, SYSTERACT, BESTER, OXYMOD
Institutions: SINTEF
Roles: PhD Student
Projects: STREAM, SYSTERACT, INBioPharm, BioZEment 2.0, OXYMOD, BESTER, AquaHealth (ERA-BlueBio)
Institutions: SINTEF

Roles: Postdoc, Project Coordinator
There is an urgent need for novel antibiotics to fight life-threatening infections and to counteract the increasing problem of propagating antibiotic resistance. Recently, new molecular genetic and biochemical tools have provided insight into the enormous unexploited genetic pool of environmental microbial biodiversity for new antibiotic compounds. New tools for more efficiently lifting this hidden treasure are needed to strengthen competitiveness of European industry, as well as for a cost-saving
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Programme: ERASysAPP
Public web page: https://www.erasysapp.eu/calls/2nd-call/systeract
Organisms: Streptomyces coelicolor
Global metabolic switching in Streptomyces coelicolor
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
Programme: SysMO
Public web page: Not specified
Organisms: Streptomyces coelicolor
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Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
One of these activities is antibiotic production and is widespread in streptomycetes
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Snapshots: No snapshots
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Study: ScoCyc metabolic pathway curation
Organisms: Streptomyces coelicolor : M145 (wild-type / wild-type)
Models: 1 hidden item
SOPs: No SOPs
Data files: No Data files