Timeseries 1
Genotype: Wildtype (M145E)
Medium: Phosphate-limited (F134)
SEEK ID: https://fairdomhub.org/studies/28
Metabolism of Streptomyces coelicolor (SysMO STREAM)
Experimentalists: Not specified
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Created: 26th May 2010 at 15:47
Last updated: 2nd Nov 2016 at 09:38
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Projects: STREAM, SYSTERACT, INBioPharm, BioZEment 2.0, OXYMOD, BESTER
Institutions: SINTEF
https://orcid.org/0000-0002-9420-1959
Institutions: University of Tuebingen, University of Tübingen
Institutions: University of Tuebingen, University of Tübingen
Projects: SCaRAB, STREAM, SYSTERACT, INBioPharm
Institutions: SINTEF, Norwegian University of Science and Technology
Senior Research Scientist at SINTEF, Dept. of Biotechnology and Nanomedicine, Research Group Mass Spectrometry
Projects: STREAM
Institutions: INBIOTEC Leon
Projects: STREAM, SCaRAB, INBioPharm, SYSTERACT
Institutions: SINTEF
Projects: STREAM
Institutions: University of Warwick
Projects: STREAM, SilicoTryp
Institutions: University of Groningen
I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at
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Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
There is an urgent need for novel antibiotics to fight life-threatening infections and to counteract the increasing problem of propagating antibiotic resistance. Recently, new molecular genetic and biochemical tools have provided insight into the enormous unexploited genetic pool of environmental microbial biodiversity for new antibiotic compounds. New tools for more efficiently lifting this hidden treasure are needed to strengthen competitiveness of European industry, as well as for a cost-saving
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Programme: ERASysAPP
Public web page: https://www.erasysapp.eu/calls/2nd-call/systeract
Global metabolic switching in Streptomyces coelicolor
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
Programme: SysMO
Public web page: Not specified
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
One of these activities is antibiotic production and is widespread in streptomycetes
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Snapshots: No snapshots
Contributor: Jay Moore
Assay type: Metabolite Profiling
Technology type: Gas Chromatography Mass Spectrometry
Snapshots: No snapshots
Contributor: Jay Moore
Assay type: Proteomics
Technology type: Gas Chromatography Mass Spectrometry
Snapshots: No snapshots
Contributor: Jay Moore
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Contributor: Jay Moore
Assay type: Transcriptomics
Technology type: Custom Array
Snapshots: No snapshots
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Contributor: Jay Moore
Creators: Jay Moore, Juan-Francisco Martin, Antonio Rodríguez-García, Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel, Maggie Smith, Louise Thomas, Eriko Takano, Lubbert Dijkhuizen, Rainer Breitling, M. Tauqeer Alam, Anthony Palathingal, R Jansen, Maria Elena Merlo, Morris Swertz, Preben Krabben, Kay Nieselt, Wolfgang Wohlleben, Jens Reuther, David Hodgson, David Rand, David Wild, Elizabeth Wellington, Gregory Challis, Nigel Burroughs, Walid Omara, William Gaze, Brent Kiernan, Roxane Legaie
Contributor: Jay Moore
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Contributor: Jay Moore
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Contributor: Jay Moore
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Contributor: Jay Moore
Abstract (Expand)
Author: Wentzel A.,Sletta H.,Ellingsen T. E.,Bruheim P.
Date Published: 2012
Journal: Metabolites
Abstract (Expand)
Author: Wentzel A.,Bruheim P.,Overby A.,Jakobsen O. M.,Sletta H.,Omara W. A.,Hodgson D. A.,Ellingsen T. E.
Date Published: 9th Jun 2012
Journal: BMC Syst Biol
Abstract (Expand)
Author: Thomas L.,Hodgson D. A.,Wentzel A.,Nieselt K.,Ellingsen T. E.,Moore J.,Morrissey E. R.,Legaie R.,Wohlleben W.,Rodriguez-Garcia A.,Martin J. F.,Burroughs N. J.,Wellington E. M.,Smith M. C.
Date Published: 8th Dec 2011
Journal: Mol Cell Proteomics
Abstract (Expand)
Author: Iqbal M.,Mast Y.,Amin R.,Hodgson D. A.,Wohlleben W.,Burroughs N. J.
Date Published: 13th Mar 2012
Journal: Nucleic Acids Res
Abstract (Expand)
Author: Battke F.,Herbig A.,Wentzel A.,Jakobsen O. M.,Bonin M.,Hodgson D. A.,Wohlleben W.,Ellingsen T. E.,Nieselt K.
Date Published: 25th Mar 2011
Journal: Adv Exp Med Biol
Abstract (Expand)
Authors: Kay Nieselt, Per Bruheim, Alexander Wentzel, Øyvind Jakobsen, Håvard Sletta, M. Tauqeer Alam, Maria Elena Merlo, Jay Moore, Walid Omara, Antonio Rodríguez-García, Louise Thomas, Roxane Legaie, William Gaze, Gregory Challis, R Jansen, Lubbert Dijkhuizen, David Rand, David Wild, Jens Reuther, Wolfgang Wohlleben, Maggie Smith, Nigel Burroughs, Juan-Francisco Martin, David Hodgson, Eriko Takano, Rainer Breitling, Trond Ellingsen, Elizabeth Wellington, Battke Florian,Herbig Alexander,Morrissey Edward R,Juarez-Hermosillo Miguel A,Nentwich Merle,Iqbal Mudassar,Bonin Michael
Date Published: 28th May 2009
Journal: BMC Genomics
