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Genotype: Wildtype (M145E)
Medium: Phosphate-limited (F134)
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Creators
Alexander Wentzel
M. Tauqeer Alam
Sven Even Borgos
Rainer Breitling
Per Bruheim
Nigel Burroughs
Gregory Challis
Lubbert Dijkhuizen
Trond Ellingsen
William Gaze
David Hodgson
Sunniva Hoel
Øyvind Jakobsen
R Jansen
Brent Kiernan
Preben Krabben
Roxane Legaie
Juan-Francisco Martin
Maria Elena Merlo
Jay Moore
Kay Nieselt
Walid Omara
Anthony Palathingal
David Rand
Jens Reuther
Antonio Rodríguez-García
Håvard Sletta
Maggie Smith
Morris Swertz
Eriko Takano
Louise Thomas
Elizabeth Wellington
David Wild
Wolfgang Wohlleben
Anders Øverby
Submitter
Views: 2893
Created: 26th May 2010 at 15:47
Last updated: 2nd Nov 2016 at 09:38
Related items
- People (35)
- Projects (2)
- Investigations (1)
- Assays (4)
- Data files (2+3)
- SOPs (10+1)
- Publications (6)
Projects: STREAM
Institutions: University of Groningen
Expertise: Mathematical modeling, Phylogentics
Tools: Flux balance analysis
Mathematical modeling, bioinformatics
Projects: SCaRAB, STREAM, SYSTERACT, INBioPharm
Institutions: SINTEF, Norwegian University of Science and Technology
Roles: Postdoc
Expertise: Bioinformatics, Microarray analysis, Data analysis, Pseudomonas, Streptomyces, Stoichiometric modelling, Prokaryotic genetics, Analytical chemistry
Tools: Transcriptomics, Perl, Fermentation, GC and LC analysis of metabolites, Pathway Tools, MS imaging, Mass spectrometry (LC-MS/MS), Mass spectrometry, FT-ICR-MS, Field Flow Fractionation
Senior Research Scientist at SINTEF, Dept. of Biotechnology and Nanomedicine, Research Group Mass Spectrometry
Projects: STREAM, SilicoTryp
Institutions: University of Groningen
Roles: Project Coordinator
Expertise: Transcriptomics, Metabolomics, Systems Biology
I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at
...
Projects: STREAM, SCaRAB, WineSys, INBioPharm
Institutions: SINTEF, Norwegian University of Science and Technology
Expertise: Metabolomics
Projects: STREAM
Institutions: University of Warwick
Projects: STREAM
Institutions: University of Warwick
Projects: STREAM
Institutions: University of Groningen
Projects: STREAM, SCaRAB, INBioPharm, SYSTERACT
Institutions: SINTEF
Projects: STREAM
Institutions: University of Warwick
Projects: STREAM
Institutions: University of Warwick
Projects: STREAM
Institutions: University of Groningen
Projects: STREAM
Institutions: University of Warwick
Projects: STREAM
Institutions: University of London UCL
Projects: STREAM
Institutions: University of Warwick
Research fellow in Bioinformatics at the Warwick Systems Biology Centre, University of Warwick.
Working on high throughput data analysis (microarray data, next generation sequencing) and data integration (database management, text-mining, gene annotation via public databases)...
Projects: STREAM
Institutions: INBIOTEC Leon
Projects: STREAM
Institutions: University of Groningen
Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
Institutions: University of Tuebingen, University of Tübingen
There is an urgent need for novel antibiotics to fight life-threatening infections and to counteract the increasing problem of propagating antibiotic resistance. Recently, new molecular genetic and biochemical tools have provided insight into the enormous unexploited genetic pool of environmental microbial biodiversity for new antibiotic compounds. New tools for more efficiently lifting this hidden treasure are needed to strengthen competitiveness of European industry, as well as for a cost-saving
...
Programme: ERASysAPP
Public web page: https://www.erasysapp.eu/calls/2nd-call/systeract
Organisms: Streptomyces coelicolor
Global metabolic switching in Streptomyces coelicolor
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
Programme: SysMO
Public web page: Not specified
Organisms: Streptomyces coelicolor
All contributors
Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.
One of these activities is antibiotic production and is widespread in streptomycetes
...
Snapshots: No snapshots
Submitter: Jay Moore
Assay type: Metabolite Profiling
Technology type: Gas Chromatography Mass Spectrometry
Snapshots: No snapshots
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Study: Timeseries 1
Organisms: Streptomyces coelicolor : M145 (wild-type / wild-type) (batch)
SOPs: MCF derivatization, Metabolome extraction, Spore batch generation
Data files: 1 hidden item
Submitter: Jay Moore
Assay type: Proteomics
Technology type: Gas Chromatography Mass Spectrometry
Snapshots: No snapshots
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Study: Timeseries 1
Organisms: Streptomyces coelicolor : M145 (wild-type / wild-type) (batch)
SOPs: No SOPs
Data files: 2 hidden items
Submitter: Jay Moore
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Study: Timeseries 1
Organisms: Streptomyces coelicolor : M145 (wild-type / wild-type) (batch)
SOPs: Cell dry weight (CDW) determination of Streptom..., Contamination test of Streptomyces coelicolor c..., Generation of cell material from Streptomyces c..., Generation of cell material from Streptomyces c..., Generation of cell material from Streptomyces c..., Preparation of inoculum for Streptomyces coelic..., Sampling from Streptomyces coelicolor culture f... and 1 hidden item
Data files: Fermentor 199 cultivation data
Submitter: Jay Moore
Assay type: Transcriptomics
Technology type: Custom Array
Snapshots: No snapshots
Investigation: Metabolism of Streptomyces coelicolor (SysMO ST...
Study: Timeseries 1
Organisms: Streptomyces coelicolor : M145 (wild-type / wild-type) (batch)
SOPs: No SOPs
Data files: Fermentor 199 transcriptomics
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST...
Studies: Timeseries 1
Assays: Online/offline measurements
All contributors
Creators: Jay Moore, Juan-Francisco Martin, Antonio Rodríguez-García, Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel, Maggie Smith, Louise Thomas, Eriko Takano, Lubbert Dijkhuizen, Rainer Breitling, M. Tauqeer Alam, Anthony Palathingal, R Jansen, Maria Elena Merlo, Morris Swertz, Preben Krabben, Kay Nieselt, Wolfgang Wohlleben, Jens Reuther, David Hodgson, David Rand, David Wild, Elizabeth Wellington, Gregory Challis, Nigel Burroughs, Walid Omara, William Gaze, Brent Kiernan, Roxane Legaie
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST...
Studies: Timeseries 1
Assays: transcriptomics
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 2 hidden items
Assays: metabolomics and 2 hidden items
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST...
Studies: Timeseries 1
Assays: metabolomics
Creators: Trond Ellingsen, Øyvind Jakobsen, Per Bruheim, Håvard Sletta, Anders Øverby, Sven Even Borgos, Sunniva Hoel, Alexander Wentzel
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST...
Studies: Timeseries 1
Assays: metabolomics
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Creators: Per Bruheim, Trond Ellingsen, Sunniva Hoel, Øyvind Jakobsen, Håvard Sletta, Alexander Wentzel, Anders Øverby, Strøm, A
Submitter: Jay Moore
Investigations: Metabolism of Streptomyces coelicolor (SysMO ST... and 1 hidden item
Studies: Timeseries 1 and 8 hidden items
Assays: Online/offline measurements and 8 hidden items
Abstract (Expand)
Authors: A. Wentzel, P. Bruheim, A. Overby, O. M. Jakobsen, H. Sletta, W. A. Omara, D. A. Hodgson, T. E. Ellingsen
Date Published: 9th Jun 2012
Publication Type: Not specified
PubMed ID: 22676814
Citation: BMC Syst Biol. 2012 Jun 7;6:59. doi: 10.1186/1752-0509-6-59.
Abstract (Expand)
Authors: M. Iqbal, Y. Mast, R. Amin, D. A. Hodgson, W. Wohlleben, N. J. Burroughs
Date Published: 13th Mar 2012
Publication Type: Not specified
PubMed ID: 22406834
Citation: Nucleic Acids Res. 2012 Jul;40(12):5227-39. doi: 10.1093/nar/gks205. Epub 2012 Mar 9.
Abstract (Expand)
Authors: A. Wentzel, H. Sletta, T. E. Ellingsen, P. Bruheim
Date Published: 2012
Publication Type: Not specified
PubMed ID: 24957373
Citation: Metabolites. 2012 Feb 17;2(1):178-94. doi: 10.3390/metabo2010178.
Abstract (Expand)
Authors: L. Thomas, D. A. Hodgson, A. Wentzel, K. Nieselt, T. E. Ellingsen, J. Moore, E. R. Morrissey, R. Legaie, W. Wohlleben, A. Rodriguez-Garcia, J. F. Martin, N. J. Burroughs, E. M. Wellington, M. C. Smith
Date Published: 8th Dec 2011
Publication Type: Not specified
PubMed ID: 22147733
Citation: Mol Cell Proteomics. 2012 Feb;11(2):M111.013797. doi: 10.1074/mcp.M111.013797. Epub 2011 Dec 6.
Abstract (Expand)
Authors: F. Battke, A. Herbig, A. Wentzel, O. M. Jakobsen, M. Bonin, D. A. Hodgson, W. Wohlleben, T. E. Ellingsen, K. Nieselt
Date Published: 25th Mar 2011
Publication Type: Not specified
PubMed ID: 21431541
Citation: Adv Exp Med Biol. 2011;696:3-15. doi: 10.1007/978-1-4419-7046-6_1.
All contributors
Abstract (Expand)
Authors: , Florian Battke, Alexander Herbig, , , , , , , , , Edward R Morrissey, Miguel A Juarez-Hermosillo, , Merle Nentwich, , Mudassar Iqbal, , , , , , , , Michael Bonin, , , , , , , , , ,
Date Published: 28th May 2009
Publication Type: Not specified
PubMed ID: 20053288
Citation: