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SysMO356 Independent Projects19 ERASysAPP15 e:Bio11 FAIRDOM11 de.NBI Systems Biology Service Center (de.NBI-SysBio)8 Era CoBioTech8 Disease Maps7 SARCHI: Mechanistic modelling of health and epidemiology5 HUMET5 Model repository for M4 (Make Me My Model) clients of ISBE5 The Digital Salmon4 LiSyM - Systems Medicine of the Liver4 e:med3 Systems Biology Programme3 German Association for Medical Informatics, Biometry and Epidemiology (GMDS)3 DFG founded projects3 Journals2 NIBSys2 COMBINE (Computational Modeling in Biology Network)2 Innate immunity2 BlueBio ERA-NET COFUND2 Drug development for neglected parasitic diseases2 FAIR Biocatalysis2 EU Projects2 MS_DILI1 BioZEment1 SAFE-Aqua1 DLN - OXYMOD1 Auromega1 ERNEST - European Research Network on Signal Transduction1 nfdi4health - German National Research Data Infrastructure for Personal Health Data1 Hallmarks of cancer 1 ISBE.NL service programme1 Thermodynamics and kinetics for Biology1 M-era.Net 3D4D21 NL-Bioimaging: FAIR-DM 1 More...

PSYSMO52 BaCell-SysMO40 SysMO-LAB40 TRANSLUCENT35 STREAM35 COSMIC31 SUMO29 KOSMOBAC27 SulfoSys26 SCaRAB21 MOSES20 SilicoTryp15 SysMO DB13 FAIRDOM10 SulfoSys - Biotec9 SYSTERACT9 Noisy-Strep8 COVID-19 Disease Map7 Kinetics on the move - Workshop 20166 SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation6 ICYSB 2015 - International Practical Course in Systems Biology5 FAIRDOM user meeting5 HUMET Startup5 INBioPharm5 EraCoBiotech 2 nd call proposal preparation5 BESTER5 IMOMESIC4 GenoSysFat4 de.NBI-SysBio4 DigiSal4 Example use cases4 FAIRDOM & LiSyM & de.NBI Data Structuring Training4 Whole body modelling of glucose metabolism in malaria patients3 MESI-STRAT3 INCOME3 HOTSOLUTE3 SynBio4Flav3 PoLiMeR - Polymers in the Liver: Metabolism and Regulation3 GMDS Project Group "FAIRe Dateninfrastrukturen für die Biomedizinische Informatik"3 SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers3 FAIRDOM Community Workers3 Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population3 Modelling COVID-19 epidemics3 SDBV/HITS3 SysMO Funders2 SysMilk2 ExtremoPharm2 ZucAt2 Molecular Systems Biology2 Early Metabolic Injury (LiSyM-EMI - Pillar I)2 Chronic Liver Disease Progression (LiSyM-DP - Pillar II)2 Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF - Pillar III)2 LiSyM Core Infrastructure and Management (LiSyM-PD)2 Liver Function Diagnostics (LiSyM-LiFuDi - Pillar IV)2 Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP)2 Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)2 The Hedgehog Signalling Pathway (LiSyM-JGMMS)2 Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM)2 SBEpo - Systems Biology of Erythropoietin2 EmPowerPutida2 Make Me My Model2 Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW)2 COMBINE Multicellular Modelling2 Sustainable co-production2 Multiscale modelling of state transitions in the host-microbiome-brain network2 Yeast glycolytic oscillations2 INDIE - Biotechnological production of sustainable indole2 EnzymeML2 Computational pathway design for biotechnological applications2 AquaHealth (ERA-BlueBio)2 NMTrypI - New Medicines for Trypanosomatidic Infections2 SASKit: Senescence-Associated Systems diagnostics Kit for cancer and stroke2 CC-TOP2 BioCreative VII2 Glucose metabolism in cancer cell lines2 MESI-STRAT Review2 MESI-Review 20242 Manchester Institute for Biotechnology1 MetApp1 WineSys1 iRhythmics1 ROBUSTYEAST1 ErasysApp Funders1 Service to Milano-Bicocca with respect to their ATP-ROS model (Active NOW)1 Service to University of Lisbon (Portugal) with respect to their CFTR maturation model (Active NOW)1 Service to LCSB (Luxembourg) with respect to ROS management in Parkinson’s disease and cancer model (Active NOW)1 Service to Universidade Católica Portugues with respect to their Molecular Insight into Autism Spectrum Disorder (ASD) model (Active NOW)1 Service to Slovenia with respect to their Protease signaling network in neurodegeneration model (Active NOW)1 Service to University of Duisburg- Essen (Germany): with respect to their The Yin-Yang of Metabolism; Endometatoxicity (YYME) model (Active NOW)1 Service to Sheffield University (UK): with respect to Mitochondrial perfect adaptation model (Active NOW)1 Service to Sanquin (Amsterdam): with respect to Modelling of acute and chronic inflammation (Prospective)1 Service to Munich (Germany): with respect toCharged peptide to charged membrane binding model (Prospective)1 MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine1 Training Hunfeld1 MS_DILI1 BioZEment 2.01 SAFE-Aqua1 OXYMOD1 ROS detailed model for MSB manucript1 Steroid biosynthesis1 TRALAMINOL1 Extremophiles metabolsim1 Auromega1 OLCIR: Optimization of Lung Cancer Therapy with Ionizing Radiation1 NAD COMPARTMENTATION1 Stress granules1 MIX-UP1 COVID-19 related studies and tools in Germany1 ERNEST Mapping Group Pilot Study1 nfdi4health - German National Research Data Infrastructure for Personal Health Data1 ModeleXchange initiative1 Consensus Hallmark Annotation1 Xenophiles Systems Biology1 Thermodynamics1 Non equilibrium thermodynamics1 Book on Thermodynamics, and kinetics1 Teaching Alien Biology1 Outdated material1 WP 3: Drug release kinetics study1 Project Coordination1 SDBV ephemeral data exchanges1 The BeeProject1 Fusion-fission-mitophagy1 EbN1 Systems Biology1 NL-Bioimaging FAIR Metadata Templates1 SABIO-VIS1 FAIR Functional Enrichment1 Stochastics and bursting1 Benefit for All FAIR Data1 Implementation of Nanopore Sequencing for Detection of Treatment Induced Transcriptomic and Epitranscriptomic Changes in Leukaemic Tumour Models1 DeepCurate1 More...

University of Groningen21 Manchester Centre for Integrative Systems Biology, University of Manchester18 University of Aberdeen16 University of Rostock14 University of Greifswald13 University of Amsterdam12 University of Heidelberg11 University of Sheffield11 Wageningen University & Research11 University of Warwick11 CSIC Madrid10 Heidelberg Institute for Theoretical Studies (HITS gGmbH)10 University of Braunschweig10 University of Stuttgart10 Helmholtz Centre for Infection Research Braunschweig9 Norwegian University of Science and Technology9 SINTEF9 VU University Amsterdam8 Norwegian University of Life Sciences8 Autonomous University of Barcelona7 Max Planck Institute for Dynamics of Complex Technical Systems7 University of Newcastle7 University of Nottingham7 University of Vienna7 University of Bonn6 University of Goettingen6 University of Manchester - Department of Computer Science6 Imperial College London5 Humboldt-Universität zu Berlin5 University of Erlangen-Nuernberg5 University of Ulm5 University of Glasgow5 University of Edinburgh5 Medical University Vienna4 University of Cordoba4 University of Dortmund4 University Duisburg-Essen4 Ludwig-Maximilians University of Munich4 Institute of Physiology Academy of Sciences3 Max-Planck-Institute of Biochemistry Martinsried3 University of Hannover3 University of Leiden3 University of Tuebingen3 University of Applied Sciences Koblenz, Rhein Ahr Campus3 University of Marburg3 Stellenbosch University3 CSIC Vigo2 INBIOTEC Leon2 University of Bergen2 University of Duesseldorf2 University of Essex2 University of Stellenbosch2 Queen's University Belfast2 eGene Biotechnologie GmbH2 Chalmers University of Technology2 Beuth University of Applied Sciences Berlin2 University of Cologne2 University of Tübingen2 CSIC2 CSIC Granada1 DSM Nutritional Products Ltd.1 University Medical Centre Groningen1 University of London UCL1 University of Stavanger1 Max-Planck-Institute for terrestrial Microbiology1 BBSRC1 Forschungszentrum Jülich1 Technical University of Denmark - Systems Biology1 Technical University of Munich1 University of Luxembourg1 Universitity Duisburg-Essen1 University of Hohenheim1 FAIRDOM User meeting1 Humboldt University Berlin1 Infrastructure Systems Biology Europe1 University of Innsbruck1 Luxembourg Centre for Systems Biomedicine (LCSB)1 Warsaw University of Technology1 Systems Biology Amsterdam1 LIACS1 More...

Germany147 United Kingdom93 Netherlands50 Spain26 Norway26 Austria12 Czechia3 South Africa3 Sweden2 Switzerland1 Denmark1 Luxembourg1 Poland1 More...

Microbiology53 Molecular Biology50 Biochemistry34 Mathematical modelling26 Systems Biology24 Bioinformatics21 Bacillus subtilis16 Genetics15 Transcriptomics14 Dynamics and Control of Biological Networks13 Molecular microbiology12 Data Management11 Parameter estimation11 carbon metabolism10 Metabolomics9 Proteomics8 stress responses7 functional protein expression7 regulation of gene expression7 Metabolic Engineering7 Bacterial Cell Biology7 Software Engineering6 dynamics of biological networks6 gene regulation6 Programming5 Mathematical modelling of biosystems and bioprocesses5 Cell physiology5 Regulatory Networks5 Biotechnology5 Microarray analysis4 Escherichia coli4 Mathematical and statistical modeling4 Physics4 Mathematics4 protein secretion4 Data analysis4 Nonlinear Dynamics4 Statistical Physics4 Mathematical modelling of biological systems4 Anaerobic Microbiology4 protein-protein interactions4 Clostridium4 carbon catabolite regulation in Gram positive bacteria4 Protein-DNA-interaction4 Glycolysis4 Databases3 Streptococcus pyogenes3 Reactor models3 rapid sampling experiments3 bioreactor models3 translational control of gene expression3 phenotypic heterogeneity3 bistability3 metal ion homeostasis3 membrane biology3 Escherichia coli Membrane protein Biochemistry3 Optimal experimental design3 Mathematical modeling3 Comparative Genomics3 Synthetic Biology3 Escherichia coli physiology3 bacterial metabolism3 bacterial gene regulation3 Bacterial metabolism | Metabolic engineering3 Metabolic Pathway Analysis and Engineering Microbial Physiology Modeling of Biological Networks Industrial Systems Biotechnology White Biotechnology Strain and Process Optimization with bacteria3 Microarray experiments with prokaryotes3 Stoichiometric modelling3 computational structural biology3 quantative biology3 Data Integration3 Metabolic Networks3 Agent-based modelling2 Fermentation2 coupling metabolome and environome2 dynamics of biological networks.2 Statistically and biologically inspired optimization algorithms2 Deterministic modelling of gene regulation networks2 Gram positive bacteria (Bacillus2 Lactococcus2 sporulation2 Signal transduction in Gram-negative bacteria; Synthetic Microbiology; Single cell gene expression; Regulatory networks; biochemistry; histidine kinase/response regulator systems2 sensitivity analysis2 Dynamic optimization.2 Phylogenetics2 pH dependent dynamic shift experiments of continuous cultures2 Microbiology Biochemistry Molecular biology Genetics Enzymology Synthetic biology Regulatory metabolic networks2 Mathematical modelling; Nonlinear Dynamics; Time Series Analysis; network theory2 Clostridial Genetics2 protein-RNA interactions2 Signalling networks2 microscopy2 localisation studies2 E. coli2 Cellular biology of metals2 HPLC2 Microbiology/ Protein chemistry/ Molecular biology2 bacterial physiology2 X-ray crystallography Structural biology2 Streptomyces2 Carbohydrate Metabolism of Archaea2 genetic engineering2 genome-scale modeling2 Streptococcus pneumoniae2 yeast2 Kinetic modelling2 standards2 semantics2 fungi2 Distributed Systems2 Cheminformatics1 Single Cell analysis1 Chip-chip1 Enterococcus faecalis1 Saccharomyces cerevisiae1 Sulfolobus solfataricus1 Information Retrieval1 Data analysis Mathematical modelling Bioinformatics Systems biology1 translatome1 folding pathways1 Streptococcus)1 competence1 germination1 antimicrobial peptides1 C- and N- metabolism1 pathogens1 virulence factors1 protein-lipid interactions1 physicochemical properties of membranes1 Recombineering1 Dynamic modelling1 Phylogentics1 Database and data warehouse design1 High-throughput sequence analysis1 Time Series Analysis1 Pathogenesis1 Bacterial metabolism | Metabolic engineering | Quorum sensing (bacterial cell-cell communication) | Developmental processes in prokaryotes |1 Biophysics1 Mycoplasma pneumoniae1 Mathemical Modeling (in particular: Thermodynamic-Kinetic Modeling)1 model reduction1 reduced-order modeling1 fluorescence protein fusions (transcriptional and translational)1 Microarray Data Analysis1 Microbiology Biochemistry Molecular biology Genetics Regulatory networks Bacterial Cell Biology1 fluorescence protein fusions1 Genetics)1 computational economics. Biology: molecular biology1 tissue biology1 social insects.1 staphylococcus aureus1 stress responses Structural biology1 Salmonella1 Chemostats1 Flux analysis Bioenergetics of growth1 Modelling of genetic and signalling networks1 biomechanics1 homogenisation.1 Microarray printing1 Database design1 Microbiology/Anaerobic Bacteria/Clostridia Molecular Physiology Stress responses1 stress adaptation of Gram-positiv bacteria1 application of functional genomics technologies in microbiology1 interaction analyses of transcriptional regulators1 analysis and preparation of diagnostic markers for Helicobacter pylori infections Yersiniosis and collagenoses1 Microbiology/ Protein chemistry/ Molecular Biology1 expression systems for pro- and eukayotes1 screening systems for nuclear transport and alternative splicing1 inducible mammalian cell death.1 Software Architecture1 biochemical1 Pseudomonas1 Prokaryotic genetics1 Reconstruction of metabolic pathways1 Regulation of carbohydrate metabolism1 Genome based Taxonomy1 Culture Collection1 Extremophiles1 chemical engineering1 enzyme kinetics1 Biology1 protein interactions1 molecular modeling1 molecular simulation1 Molecular Interactions1 biophysical chemistry1 genetics of archaea1 metagenomics1 cultivation of extremophiles1 REST1 Thermodynamics1 Machine Learning1 Ma1 Limit cycle oscillations1 mRNA1 overflow metabolism in Bacillus1 Genetic regulation1 Medical microbiology1 Food Microbiology1 Listeria monocytogenes1 network inference1 motif detection1 Trypanosoma brucei1 Streptococcus pneumoniae Molecular microbiology, Bacterial Cell Biology, Genetics1 Computational modelling1 metabolism1 sequencing1 VREs1 Cloud computing1 Phytopathology1 Human-Computer Interaction1 Analytical chemistry1 Data curation1 Agile development1 Docker1 Archaeal physiology1 Hyperthermophiles1 Thermoacidohiles1 Curation1 Ontology1 Computational Biology1 Data Modelling1 Kinetics1 More...

Matlab31 Transcriptomics28 Biochemistry and protein analysis23 Molecular Biology22 Microbiology21 Computational and theoretical biology21 Fermentation21 ODE20 Molecular biology techniques (RNA/DNA/Protein)20 Microarray analysis17 Genetic modification15 Computational Systems Biology14 Mathematica13 Dynamic modelling13 Proteomics (2D-PAGE)11 Biochemistry10 Metabolomics10 Chromatography10 Proteomics9 SBML9 Copasi9 Stochastic models9 Genetics8 Bioinformatics8 R8 Fluorecence based reporter gene analyses/single cell analyses8 qRT-PCR8 Data Management7 Python7 linux7 Fluorescence and confocal microscopy7 Genomics6 Databases6 Java6 differential algebraic equations6 continuous cultivation6 molecular biological techniques (RNA/DNA techniques6 Mass spectrometry (LC-MS/MS)6 Genetic analysis5 Model organisms5 Partial differential equations5 Perl5 stimulus response experiments5 fluorescence spectroscopy5 quantitative western blot analysis5 Deterministic models5 HPLC5 Cell culture5 Spectroscopy and structural analysis4 Web services4 PCR4 Ruby on Rails4 Material balance based modeling4 Enzyme assay4 data modeling4 C programming4 MySQL4 Molecular biology techniques (RNA/DNA)4 time lapse microscopy4 2-D Gel Electrphoresis4 HTML4 Metabolic Engineering4 Bioconductor Packages in R4 microbiology techniques4 Parameter estimation4 Cell biology3 Single Cell analysis3 Workflows3 Chip-chip3 Taverna3 SQL3 evaluation of process dynamics3 Protein chemical methods (protein overproduction3 enzymatic analyses3 mutant strain generation3 quantitative western blot analyses3 XPPAUT3 Membrane protein biochemistry3 Flux balance analysis3 DNA technology RNA technology Protein analysis Fermentation Mutagenesis3 GC and LC analysis of metabolites3 Chemostat culture3 Mutant and Strain Construction3 Enzyme assays3 reporter gene analyses3 Western blot analyses3 stochastic methods3 DNA3 analysis of functional genomics data3 interaction analysis techniques especially SPR measurements3 enzyme kinetics3 semantic web3 Javascript3 SEEK3 Algebraic equations2 Linear equations2 JWS Online2 rtPCR2 qtPCR2 Mass spectrometry2 Ruby2 Ontologies2 PHP2 DIVA2 quantitative Western analyses)2 qPCR2 Northern analyses)2 northern blot analysis2 including:- Dynamic modelling- Parameter estimation- Optimal experimental design- Dynamic optimization2 Biochemistry of substrate transport. molecular biological techniques (RNA/DNA techniques analyses of transport across cell membranes heterologous expression of transporters2 Chemical cross-linking2 Site-directed mutagenesis2 transcriptional analysis (Northern blots2 Optimal experimental design2 Proteomics (Glycoproteins)2 BioMart2 Comparative Genomics2 GC and LC analysis of metabolites | Analysis of signal molecules | Handling of anaerobic bacteria |2 SubtiWiki2 protein-DNA interactions; gel shifts; footprints; in vitro transcription protein ligan interactions2 absolute quantification2 Flow cytometry2 Immunofluorescence2 molecular biological techniques (RNA/DNA techniques)2 protein interaction studies2 In silico Metabolic Network Analysis2 fed-batch cultivation2 RNA / DNA Techniques2 bacterial chemostat culture2 spectroscopy2 site-directed and random mutagenesis2 Mutant and Strain Construction; RNA / DNA Techniques; RT-RealTime-PCR; 2D-Gels; Metabolite Analysis; Bioreactor Experiments; Flow Cyometry; Microscopy; Single Cell analysis2 Chemostats2 Proteins2 Gaschromatographic analysis2 gel-based and gel-free proteomics2 Statistical tools2 shotgun proteomics2 in vivo crosslinking2 PIPSA2 SYCAMORE2 fortran2 transcription analysis2 NMR2 Perl programming2 RNA interference2 protein purification2 phage techniques2 GC and LC/MS analysis of metabolites2 COBRA toolbox2 Cell and tissue culture1 Isolation purification and separation1 Pharmacology and toxicology1 Spring1 semanticSBML1 MIRIAM1 ProMOT1 J2EE1 pulsed - FRAP1 purification1 molecular biological techniques (RNA/DNA techniques analyses of transport across cell membranes heterologous expression of transporters1 cultivation1 Biochemistry of substrate transport. molecular biological techniques (RNA/DNA techniquesanalyses of transport across cell membranesheterologous expression of transporters1 FRAP1 including: - Dynamic modelling - Parameter estimation - Optimal experimental design - Dynamic optimization1 Fluorescence and confocal microscopy FRAP/FLIP1 FACS1 genomic array footprinting1 gene regulation1 The Membrane Enzymology group focuses on the molecular mechanisms of transport and signalling across biological membranes. In other words: How do molecules permeate biological membranes and how at the level of protein molecules are environmental signals s1 engineering principles and approaches from molecular biology and synthetic chemistry are applied. Confocal microscopy and various spectroscopic methods are used to analyze processes at the single cell or even single molecule level.1 PDE1 C programing1 quantitative RT-PCR); quantitative Western blot analysis; protein purification; reconstitution of membrane-integrated proteins; Biochemistry of substrate transport; Fluorecence based reporter gene analyses/single cell analyses1 surface plasmon resonance spectroscopy; site-directed spin labeling and EPR analysis;1 Dynamic optimization1 Systems Biology1 Time-lapse fluorescence microscopy Flow cytometry1 EnsEMBL1 XML1 Phylogenetics1 methods of nonlinear time series analysis1 programming in C1 site-directed spin labeling and EPR spectroscopy1 isothermal titration calorimetry1 Biophysics1 SPINE1 bacterial two-hybrid system1 bacterial chamostat culture1 time-resolved microarray analysis1 GeLC-MS/MS1 metabolic labeling1 AQUA1 Logical modelling1 trac (wiki for data management)1 Fluxomics1 Fluorescence microscopy1 transposon mutagenesis1 Time-lapse fluorescence microscopy1 FLAME - Flexible Large-scale Agent-based Modelling Framework.1 GFP expression1 live cell array1 X-ray crystallography electron microscopy Biochemistry and protein analysis1 Bioreactor experiments/Fermentation (batch1 Chemostat)1 2D-PAGE1 plasmon resonance spectroscopy1 phage transduction1 Molecular biology techniques (DNA/Protein)1 Chemostat culture GC and LC analysis of metabolites1 Multiscale and multiphysics modelling1 asymptotic methods1 network theory1 model reduction.1 RNA1 Gaschromatography1 Creation of Mutants1 stress experiments1 Groovy1 Protein1 Mutant construction1 2-D Gel Electrophoresis1 Chemostat cultures Molecular biology techniques (RNA/DNA) 2-D Gel electrophoresis Gaschromatography Protein overexpression/purification1 molecular biology techniques1 molecular biological1 microbiological and immunological techniques1 surface plasmon resonance spectroscopy1 reporter gene analysis1 X-ray crystallographyelectron microscopyBiochemistry and protein analysis1 Maple1 Clustering softwares1 Pathway Tools1 affinity copurification/precipitation1 model prediction testing1 reverse engineering1 computational platform development1 metabolic netwlrk visualization1 gPROMS1 SABIO-RK http://sabio.villa-bosch.de/1 Molecular Dynamics1 molecular modeling and simulation1 Protein and RNA structure prediction1 Homology Modelling1 Programming in perl and tcl1 Grails web development framework1 iTRAQ for quantitative proteomics1 madonna1 genetics of hyperthermophilic archaea1 phylogeny1 CUDA1 GPU1 Thermodynamics1 Machine Learning1 SABIO-RK database1 in vitro transcription1 DNA affinity chromatography1 EMSA1 RightField1 PySCeS1 RNAseq1 Bayesian inference1 Physiology1 Protege1 Bioreactor experiments1 web development1 AWS1 Research Objects1 SABIO-RK1 MS imaging1 FT-ICR-MS1 Field Flow Fractionation1 Docker1 Kinetic Modeling1 Data Modelling1 More...