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1172 Assays visible to you, out of a total of 2143

This is a model of the circadian clock of Ostreococcus tauri, with a single negative feedback loop between TOC1 and CCA1 (a.k.a. LHY), and multiple light inputs. It was used and described in Troein et al., Plant Journal (2011). The model has been tested in Copasi, where it reproduces the behaviour of the original (which consisted of equations loaded from a text file by a more or less custom C++ program).Comments Not formulated to easily allow addition of the ISSF to replace the present light ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: Troein Ostreococcus clock 1-loop - PLM_7

"TRIFFID (Top-down Representation of Interactive Foliage and Flora Including Dynamics)" is a dynamic global vegetation model, which updates the plant distribution and soil carbon based on climate-sensitive CO2 fluxes at the land-atmosphere interface. The surface CO2 fluxes associated with photosynthesis and plant respiration are calculated in the MOSES 2 tiled land-surface scheme (Essery et al (In preparation)), on each atmospheric model timestep (normally 30 minutes), for each of 5 plant functional ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Muetzelfeldt, Robert

Study: TRIFFID - PLM_5

Cytoscape silqueue specific protein detection

Originally submitted to PLaSMo on 2012-03-02 12:44:13

Cytoscape shoot specific diurnal transcript oscillation.

Originally submitted to PLaSMo on 2012-03-02 12:42:30

The seed network, uploaded as a test from Cytoscape

Version Comments

Uploading new version for testing



Originally submitted to PLaSMo on 2012-02-24 11:41:50

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Graf, Alexandra

Study: TiMet 2011 seed network - PLM_53

The seed network, uploaded as a test from Cytoscape

Version Comments

Saving second/third version as a live test



Originally submitted to PLaSMo on 2012-02-24 11:41:50

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Graf, Alexandra

Study: TiMet 2011 seed network - PLM_53

Test for root network

Originally submitted to PLaSMo on 2012-02-27 14:24:59

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Graf, Alexandra

Study: TiMet 2011 Root network - PLM_55

PP interaction network exported from Cytoscape in XGMML

Originally submitted to PLaSMo on 2012-03-02 12:32:33

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Graf, Alexandra

Study: TiMet 2011 PP interaction network - PLM_56

Trial upload of the pollen netwrok from TiMet

Version Comments

Live pollen upload test



Originally submitted to PLaSMo on 2012-02-27 12:17:46

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Graf, Alexandra

Study: TiMet 2011 Pollen network - PLM_54

Trial upload of the pollen netwrok from TiMet

Originally submitted to PLaSMo on 2012-02-27 12:17:46

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Graf, Alexandra

Study: TiMet 2011 Pollen network - PLM_54

TiMet flower specific protein detection network

Originally submitted to PLaSMo on 2012-03-02 12:39:54

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the degradation rate of TOC1 has been eliminated by setting the rate to the value it had in the light in the original model. This model was used to generate Figure 2D in Dixon et al. New Phytologist (2014)Related Publications Laura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, TOC1 degr L - PLM_89

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the degradation rate of TOC1 has been eliminated by setting the rate to the value it had in the light in the original model. This model was used to generate Figure 2D in Dixon et al. New Phytologist (2014)Related Publications Laura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, TOC1 degr L - PLM_89

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the degradation rate of TOC1 has been eliminated by setting the rate to the value it had in the dark in the original model. This model was used to generate Figure 2D in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses to ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, TOC1 degr D - PLM_90

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the activation rate of TOC1 has been eliminated by setting the rate to the value it had in the light in the original model. This model was used to generate Figure 2E in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses to ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, TOC1 act L - PLM_91

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the activation rate of TOC1 has been eliminated by setting the rate to the value it had in the dark in the original model. This model was used to generate Figure 2E in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses to ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, TOC1 act D - PLM_92

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the transcription rate of CCA1 has been eliminated by setting the rate to the value it had in the light in the original model. This model was used to generate Figure 2C in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, CCA1 prod L - PLM_87

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the transcription rate of CCA1 has been eliminated by setting the rate to the value it had in the dark in the original model. This model was used to generate Figure 2C in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, CCA1 prod D - PLM_88

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the degradation rate of CCA1 has been eliminated by setting the rate to the value it had in the light in the original model. This model was used to generate Figure 2B in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, CCA1 degr L - PLM_85

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where light input to the degradation rate of CCA1 has been eliminated by setting the rate to the value it had in the dark in the original model. This model was used to generate Figure 2B in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses to ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, CCA1 degr D - PLM_86

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where the light accumulator (acc) has been eliminated by setting its value to 1. This model was used to generate Figure 2F in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses to environmental signals. New Phytologist. Originally submitted to ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, acc on - PLM_84

This is a version of the T2011.1.2 Ostreococcus tauri 1-loop clock model where the light accumulator (acc) has been eliminated by replacing it with immediate light input. This model was used to generate Figure 2F in Dixon et al. New Phytologist (2014)Related PublicationsLaura E. Dixon, Sarah K. Hodge, Gerben van Ooijen, Carl Troein, Ozgur E. Akman, Andrew J. Millar (2014). Light and circadian regulation of clock components aids flexible responses to environmental signals. New Phytologist. Originally ...

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Troein, Carl

Study: T2011 Ostreococcus clock, acc immediate - PLM_83

The model is applied to spring wheat, with ample supply of nutrients and water, also without pests, diseases and weeds. Radiation and temperature, being the most important environmental factors, and crop characteristics determine growth and development. Crop growth and development are simulated based on underlying chemical, physiological and physical processes. Dry matter accumulation is calculated from daily crop CO2 assimilation based on leaf CO2 assimilation and taking into account the respiration ...

This model, derived from Biomodels299, is a variant of the Neurospora Circadian clock model of Leloup et al., 1999. It is supplemented with a periodic light function (SBO:0000475) that is parameterized to produce sinusoidal oscillations in the light sensitive parameter Vs with an amplitude of 5. These sinusoidal wave-form maintains entrained oscillations even with high light input, and is described in Figures 6 and 7 of Gonze and Goldbeter, 2000.Related PublicationsDidier Gonze and Albert Goldbeter ...

 This model is derived from Biomodels 299 - the Leloup et al Neurospora clock model. This variant contains an embedded light-forcing function (SBO:000475) that provides a periodic light input. In this model, after 72h of LD12:12, the amplitude of Vs ( the light dependent parameter ) increases to 4.1, leading to chaotic oscillations. For this to happen, the periodic light function needs to produce a square-wave pattern.    Execution of this model will result in the behaviour depicted in Figure 2D ...

Neuronal musch signalling sbml diagram

Originally submitted to PLaSMo on 2012-03-05 12:33:43

Submitter: BioData SynthSys

Biological problem addressed: Gene Regulatory Network

Investigation: Beaton, Martin

Study: Neuronal muscle signalling - PLM_63

This is a modified version of Biomodels89, containing a light-forcing function. This variant is configured to run cycles of LD8:16Related Publicationsocke JC, Kozma-Bognár L, Gould PD, Fehér B, Kevei E, Nagy F, Turner MS, Hall A, Millar AJ. (2006). Experimental validation of a predicted feedback loop in the multi-oscillator clock of Arabidopsis thaliana. . Mol Syst Biol . Originally submitted to PLaSMo on 2012-03-29 10:24:44

Model files accompanying Seaton et al., Molecular Systems Biology, 2015 Abstract: Clock?regulated pathways coordinate the response of many developmental processes to changes in photoperiod and temperature. We model two of the best?understood clock output pathways in Arabidopsis, which control key regulators of flowering and elongation growth. In flowering, the model predicted regulatory links from the clock to CYCLING DOF FACTOR 1 (CDF1) and FLAVIN?BINDING, KELCH REPEAT, F?BOX 1 (FKF1) transcription. ...

Validation: Validated against the original running in Excel. Each calculation in the model was individually validated as well. Comments on numerical integration: Euler integration with time steps of 1. In Simile the "time units" were set to "day" and execution was for 364 days as the simulation starts at time 0 (not time 1 as in the Excel model). Comments on running Simile model: Users must specify the temperature controlled growing season themselves. To do this use the following steps which take ...

This is a very simple generic vegetation model, with just one state variable (plant biomass), and two processes: assimilation and respiration.   In the original paper, the model is used twice, once for the trees and once for the grass under the trees, with the grass receiving light not intercepted by the trees.   The model provided here is just for a single vegetation component.Related PublicationsMcMurtrie RE, Wolf L (1983). A model of competition between trees and grass for radiation, water and ...

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