Publications

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ABSTRACT: BACKGROUND: With increased experimental availability and accuracy of bio-molecular networks, tools for their comparative and evolutionary analysis are needed. A key component for such studies ...

Authors: Michal Kolar, Jörn Meier, Ville Mustonen, Michael Lässig, Johannes Berg

Date Published: 21st Nov 2012

Journal: BMC Syst Biol

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Methylmercury (MeHg) is a widely distributed contaminant polluting many aquatic environments, with health risks to humans exposed mainly through consumption of seafood. The mechanisms of toxicity of ...

Authors: Fekadu Yadetie, O. A. Karlsen, A. Lanzen, K. Berg, P. Olsvik, C. Hogstrand, A. Goksoyr

Date Published: 30th Oct 2012

Journal: Aquat Toxicol

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In Escherichia coli several systems are known to transport glucose into the cytoplasm. The main glucose uptake system under batch conditions is the glucose phosphoenolpyruvate:carbohydrate phosphotransferase ...

Authors: None

Date Published: 8th Oct 2012

Journal: Journal of Bacteriology

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Enterococcus faecalis V583 was grown in a glucose-limited chemostat at three different (0.05 h(-1), 0.15 h(-1) and 0.4 h(-1)) growth rates. The fermentation pattern changed with growth rate, from a ...

Authors: Ibrahim Mehmeti, Ellen M Faergestad, Martijn Bekker, Lars Snipen, Ingolf Nes, Helge Holo

Date Published: 1st Nov 2011

Journal: Applied and environmental microbiology

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Clostridium acetobutylicum is able to switch from acidogenic growth to solventogenic growth. We used phosphate-limited continuous cultures that established acidogenic growth at pH 5.8 and solventogenic ...

Authors: Christina Grimmler, Holger Janssen, Désireé Krausse, Ralf-Jörg Fischer, Hubert Bahl, Peter Dürre, Wolfgang Liebl, Armin Ehrenreich

Date Published: 6th Jan 2011

Journal: J. Mol. Microbiol. Biotechnol.

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We designed a simple graphical presentation for the results of a transcription factor (TF) pattern matching analysis. The TF analysis algorithm utilized known sequence signature motifs from several ...

Authors: None

Date Published: 19th Mar 2010

Journal: Genome Inform

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How cultures of genetically identical cells bifurcate into distinct phenotypic subpopulations under uniform growth conditions is an important question in developmental biology of relevance even to ...

Authors: None

Date Published: 10th Mar 2010

Journal: Mol. Microbiol.

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Quinones and alpha,beta-unsaturated carbonyls are naturally occurring electrophiles that target cysteine residues via thiol-(S)-alkylation. We analysed the global expression profile of Bacillus subtilis ...

Authors: Thi Thu Huyen Nguyen, Warawan Eiamphungporn, Ulrike Mäder, Manuel Liebeke, Michael Lalk, Michael Hecker, John D Helmann, Haike Antelmann

Date Published: 23rd Dec 2008

Journal: Mol. Microbiol.

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In this review, we demonstrate the power of gel-based proteomics to address physiological questions of bacteria. Although gel-based proteomics covers a subpopulation of proteins only, fundamental issues ...

Authors: Michael Hecker, Haike Antelmann, Knut Büttner, Jörg Bernhardt

Date Published: 13th Nov 2008

Journal: Proteomics

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Bacillus subtilis is a prolific producer of enzymes and biopharmaceuticals. However, the susceptibility of heterologous proteins to degradation by (extracellular) proteases is a major limitation for ...

Authors: Lidia Westers, Helga Westers, Geeske Zanen, Haike Antelmann, Michael Hecker, David Noone, Kevin M Devine, Jan Maarten Van Dijl, Wim J Quax

Date Published: 12th Jun 2008

Journal: Proteomics

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A cornerstone of biotechnology is the use of microorganisms for the efficient production of chemicals and the elimination of harmful waste. Pseudomonas putida is an archetype of such microbes due to ...

Authors: Jacek Puchałka, Matthew A Oberhardt, Miguel Godinho, Agata Bielecka, Daniela Regenhardt, Kenneth Timmis, Jason A Papin, Vitor Martins Dos Santos

Date Published: 27th Mar 2008

Journal: PLoS Comput. Biol.

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Glutamate is a central metabolite in all organisms since it provides the link between carbon and nitrogen metabolism. In Bacillus subtilis, glutamate is synthesized exclusively by the glutamate synthase, ...

Authors: Fabian M Commichau, Katrin Gunka, Jens J Landmann, Joerg Stuelke

Date Published: 7th Mar 2008

Journal: J. Bacteriol.

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The balance between the supply and utilization of carbon (C) changes continually. It has been proposed that plants respond in an acclimatory manner, modifying C utilization to minimize harmful periods ...

Authors: B. Usadel, O. E. Blasing, Y. Gibon, K. Retzlaff, M. Hohne, M. Gunther, M. Stitt

Date Published: No date defined

Journal: Plant Physiol

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INTRODUCTION: Male breast cancer (MBC) is a rare and inadequately characterized disease. The aim of the present study was to characterize MBC tumors transcriptionally, to classify them into comprehensive ...

Authors: I. Johansson, C. Nilsson, P. Berglund, M. Lauss, M. Ringner, H. Olsson, L. Luts, E. Sim, S. Thorstensson, M. L. Fjallskog, I. Hedenfalk

Date Published: No date defined

Journal: Breast Cancer Res

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