Abstract (Expand)

Gram-positive Streptomyces bacteria produce thousands of bioactive secondary metabolites, including antibiotics. To systematically investigate genes affecting secondary metabolism, we developed a ...

Author: Xu Z.,Wang Y.,Chater K. F.,Ou H. Y.,Xu H. H.,Deng Z.,Tao M.

Date Published: 8th Jan 2017

Journal: Appl Environ Microbiol

Abstract (Expand)

MOTIVATION: A major goal of drug development is to selectively target certain cell types. Cellular decisions influenced by drugs are often dependent on the dynamic processing of information. Selective ...

Authors: Bernhard Steiert, Jens Timmer, Kreutz C.

Date Published: 3rd Sep 2016

Journal: Bioinformatics

Abstract (Expand)

Clock-regulated pathways coordinate the response of many developmental processes to changes in photoperiod and temperature. We model two of the best-understood clock output pathways in Arabidopsis, ...

Authors: Daniel Seaton, Andrew Millar, Smith R. W.,Song Y. H.,MacGregor D. R.,Stewart K.,Steel G.,Foreman J.,Penfield S.,Imaizumi T.,Halliday K. J.

Date Published: 21st Jan 2015

Journal: Mol Syst Biol

Abstract (Expand)

BACKGROUND: Polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most abundant among PCBs detected in ...

Author: Yadetie F.,Karlsen O. A.,Eide M.,Hogstrand C.,Goksoyr A.

Date Published: 19th Jun 2014

Journal: BMC Genomics

Abstract (Expand)

Systems metabolomics, the identification and quantification of cellular metabolites and their integration with genomics and proteomics data, promises valuable functional insights into cellular biology. ...

Authors: Luis Serrano, Maier T.,Marcos J.,Wodke J. A.,Paetzold B.,Liebeke M.,Gutierrez-Gallego R.

Date Published: 20th Apr 2013

Journal: Mol Biosyst

Abstract (Expand)

During the last few years scientists became increasingly aware that average data obtained from microbial population based experiments are not representative of the behavior, status or phenotype of ...

Authors: Imke De Jong, Oscar Kuipers, Jan-Willem Veening, Beilharz Katrin

Date Published: 16th Aug 2011

Journal: J Vis Exp

Abstract (Expand)

Abstract A new YNB medium containing very low concentrations of alkali metal cations has been developed to carry out experiments to study potassium homoeostasis. Physiological characterization of ...

Authors: Clara Navarrete, Silvia Petrezselyova, Lina Patricia Barreto Parra, Jaromir Zahrádka, Joaquin Ariño, Hana Sychrova, Jose Ramos, Martínez José L

Date Published: 25th May 2010

Journal: Not specified

Abstract (Expand)

Protein degradation mediated by ATP-dependent proteases, such as Hsp100/Clp and related AAA+ proteins, plays an important role in cellular protein homeostasis, protein quality control and the regulation ...

Authors: Leendert Hamoen, Kirstein Janine,Strahl Henrik,Molière Noël,Turgay Kürşad

Date Published: 10th Sep 2008

Journal: Mol. Microbiol.

Abstract (Expand)

Predicting a multicellular organism's phenotype quantitatively from its genotype is challenging, as genetic effects must propagate up time and length scales. Circadian clocks are intracellular ...

Authors: Yin Hoon Chew, Daniel Seaton, Andrew Millar, Mengin Virginie,Flis Anna,Mugford Sam T.,Smith Alison M.,Stitt Mark

Date Published: No date defined

Journal: Not specified

Abstract (Expand)

Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before returning to spawn in freshwater. The transition to marine habitats is associated with dramatic changes in the ...

Authors: Gareth Gillard, Thomas Harvey, Arne Gjuvsland, Yang Jin, Magny Sidsel Thomassen, Jacob Seilø Torgersen, Torgeir R. Hvidsten, Jon Olav Vik, Sandve Simen, Lien S.,Leaver M.

Date Published: No date defined

Journal: Mol Ecol

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