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The main objective of the ERANET proposal Systems Biology Applications - ERASysAPP (app = application = translational systems biology) is to promote multidimensional and complementary European systems biology projects, programmes and research initiatives on a number of selected research topics. Inter alia, ERASysAPP will initiate, execute and monitor a number of joint transnational calls on systems biology research projects with a particular focus on applications - or in other words so called ...
Projects: SysVirDrug, SysMilk, SysMetEx, MetApp, IMOMESIC, WineSys, CropClock, SYSTERACT, XyloCut, RootBook, ROBUSTYEAST, LEANPROT, ErasysApp Funders
Web page: https://www.cobiotech.eu/about-cobiotech/erasysapp
LiSyM (Liver Systems Medicine) represents a research network of German centers and institutions, brought together by a 20 Million Euro funding program of the German Government, in which mathematicians, modelers, pharmacologists, molecular biologists and clinical scientists work together to develop a Systems Medicine approach to study early and advanced liver disease. The aim of this unique research program is to acquire and use new experimental data and data from existing data bases to build ...
Projects: Early Metabolic Injury (LiSyM-EMI - Pillar I), Chronic Liver Disease Progression (LiSyM-DP - Pillar II), Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF - Pillar III), LiSyM Core Infrastructure and Management (LiSyM-PD), Liver Function Diagnostics (LiSyM-LiFuDi - Pillar IV), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), FAIRDOM & LiSyM & de.NBI Data Structuring Training, New LiSyM project
Web page: http://www.lisym.org
Programme: LiSyM - Systems Medicine of the Liver
Public web page: Not specified
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus
Programme: LiSyM - Systems Medicine of the Liver
Public web page: Not specified
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus
IMOMESIC - Integrating Modelling of Metabolism and Signalling towards an Application in Liver Cancer
One of the most challenging questions in cancer research is currently the interconnection of metabolism and signalling. An understanding of mechanisms that facilitate the physiological shift towards a proliferative metabolism in cancer cells is considered a major upcoming topic in oncology and is a key activity for future drug development. Due to the complexity of interrelations, a systems biology ...
Programme: ERASysAPP
Public web page: Not specified
Organisms: Homo sapiens
Programme: MS_DILI
Public web page: Not specified
Organisms: Homo sapiens, Mus musculus
Abstract
Authors: Helge Hass, Carolin Loos, Elba Raimúndez-Álvarez, Jens Timmer, Jan Hasenauer, Clemens Kreutz
Date Published: 1st Sep 2019
Publication Type: Journal
DOI: 10.1093/bioinformatics/btz020
Citation: Bioinformatics 35(17):3073-3082
Abstract (Expand)
Authors: B. Steiert, J. Timmer, C. Kreutz
Date Published: 3rd Sep 2016
Publication Type: Not specified
PubMed ID: 27587694
Citation: Bioinformatics. 2016 Sep 1;32(17):i718-i726. doi: 10.1093/bioinformatics/btw461.
Abstract (Expand)
Authors: T. Maiwald, H. Hass, B. Steiert, J. Vanlier, R. Engesser, A. Raue, F. Kipkeew, H. H. Bock, D. Kaschek, C. Kreutz, J. Timmer
Date Published: 3rd Sep 2016
Publication Type: Not specified
PubMed ID: 27588423
Citation: PLoS One. 2016 Sep 2;11(9):e0162366. doi: 10.1371/journal.pone.0162366. eCollection 2016.
Abstract (Expand)
Authors: Christian Tönsing, Jens Timmer, Clemens Kreutz
Date Published: 1st Aug 2014
Publication Type: Not specified
DOI: 10.1103/PhysRevE.90.023303
Citation: Phys. Rev. E 90(2)
Abstract (Expand)
Authors: J. Bachmann, A. Raue, M. Schilling, M. E. Bohm, C. Kreutz, D. Kaschek, H. Busch, N. Gretz, W. D. Lehmann, J. Timmer, U. Klingmuller
Date Published: 2011
Publication Type: Not specified
DOI: 10.1038/msb.2011.50
Citation: Molecular Systems Biology 7(1) : 516