Computational systems biology involves integrating heterogeneous datasets in order to generate models. These models can assist with understanding and prediction of biological phenomena. Generating datasets and integrating them into models involves a wide range of scientific expertise. As a result these datasets are often collected by one set of researchers, and exchanged with others researchers for constructing the models. For this process to run smoothly the data and models must be FAIR-findable, accessible, interoperable, and reusable. In order for data and models to be FAIR they must be structured in consistent and predictable ways, and described sufficiently for other researchers to understand them. Furthermore, these data and models must be shared with other researchers, with appropriately controlled sharing permissions, before and after publication. In this chapter we explore the different data and model standards that assist with structuring, describing, and sharing. We also highlight the popular standards and sharing databases within computational systems biology.
SEEK ID: https://fairdomhub.org/publications/571
PubMed ID: 31602618
Projects: COMBINE Multicellular Modelling, COVID-19 Disease Map, FAIRDOM, LiSyM Core Infrastructure and Management (LiSyM-PD)
Publication type: Journal
Journal: Methods Mol Biol
Citation: Methods Mol Biol. 2019;2049:285-314. doi: 10.1007/978-1-4939-9736-7_17.
Date Published: 12th Oct 2019
Registered Mode: by PubMed ID
Authors: N. J. Stanford, M. Scharm, P. D. Dobson, M. Golebiewski, M. Hucka, V. B. Kothamachu, D. Nickerson, S. Owen, J. Pahle, U. Wittig, D. Waltemath, C. Goble, P. Mendes, J. Snoep
Description: Computational systems biology involves integrating heterogeneous datasets in order to generate models. These models can...
SEEK ID: https://fairdomhub.org/publications/571
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Created: 30th Jul 2020 at 16:30
Last updated: 8th Dec 2022 at 17:26


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