2 items tagged with 'standardisation'.
Abstract (Expand)
Reconstructing and understanding the Human Physiome virtually is a complex mathematical problem, and a highly demanding computational challenge. Mathematical models spanning from the molecular level … through to whole populations of individuals must be integrated, then personalized. This requires interoperability with multiple disparate and geographically separated data sources, and myriad computational software tools. Extracting and producing knowledge from such sources, even when the databases and software are readily available, is a challenging task. Despite the difficulties, researchers must frequently perform these tasks so that available knowledge can be continually integrated into the common framework required to realize the Human Physiome. Software and infrastructures that support the communities that generate these, together with their underlying standards to format, describe and interlink the corresponding data and computer models, are pivotal to the Human Physiome being realized. They provide the foundations for integrating, exchanging and re-using data and models efficiently, and correctly, while also supporting the dissemination of growing knowledge in these forms. In this paper, we explore the standards, software tooling, repositories and infrastructures that support this work, and detail what makes them vital to realizing the Human Physiome.
Authors: D. Nickerson, K. Atalag, B. de Bono, J. Geiger, Carole Goble, S. Hollmann, J. Lonien, Wolfgang Müller, B. Regierer, Natalie Stanford, Martin Golebiewski, P. Hunter
Date Published: 7th Apr 2016
Journal: Interface Focus
PubMed ID: 27051515
Citation: Interface Focus. 2016 Apr 6;6(2):20150103. doi: 10.1098/rsfs.2015.0103.
Created: 29th Dec 2016 at 17:11
Written and presented by Dagmar Waltemath (University of Rostock) as part of the Reproducible and Citable Data and Models Workshop in Warnemünde, Germany. September 14th - 16th 2015.
Creators: Natalie Stanford, Dagmar Waltemath
Contributor: Natalie Stanford
Created: 2nd Nov 2015 at 15:56, Last updated: 2nd Nov 2015 at 15:56