People

Mathematical modeling, bioinformatics

I am a Professor in Medical Systems Biology and the University Medical Centre Groningen. The research in my lab is focused on complex regulation of mammalian lipid and carbohydrate metabolism, eventually aiming at network-based therapies. We combine dynamic computer simulations with quantitative metabolomics, 13C fluxomics, proteomics and transcriptome analysis, and in depth biochemical analysis. This allows to predict and understand ‘emergent’ properties, those properties that are counterintuitive ...

I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at ...

ESR14

Group leader Molecular Genetics

MESI-STRAT Project Manager

PhD student. Analyzing CcpA affinity to cre boxes (catabolite responsive elements) and response of B. subtilis to membrane protein overproduction stress.

Kosmobac, WP3, looking at diffusion of macromolecules in vivo (in E.coli cells) and cell responses to osmotic shock using confocal (fluorescence) microscopy especially pulsed - FRAP

Bert Poolman is professor in biochemistry and program director of the Centre for Synthetic Biology. His research focuses on the elucidation of the mechanisms by which signals are transduced and small molecules are translocated across cellular membranes. Cells are reengineered for the production of correctly folded membrane proteins, and methods are developed to reconstitute complex molecular assemblies in synthetic membranes and to analyze their functional and structural properties. The in vitro ...

Prof. Dr. Kathrin Thedieck MESI-STRAT Coordinator Leader WP8 – Project Coordination