Uwe Voelker
By training I am a molecular microbiologist with a particular interest in bacterial stress adaptation reactions. Since the early 90ies we have used functional genomics technologies, particularly proteomics, to investigate the response of Bacillus subtilis to environmental challenges. I am currently Head of the Functional Genomics Department of the Interfaculty Institute of Genetics and Functional Genomics at the Ernst-Moritz-Arndt-University Greifswald. Within the Department we are applying functional genomics technologies in a diverse range of projects ranging from microbiology (stress adaptation reactions in Bacillus subtilis and Pseudomonas fluorescens) via the study of host-pathogen interactions (S. aureus vs. murine and human host cels) to the analysis of predisposition to disease (genomewide association studies) and the anaysis of pathophysiology of selected diseases and response to therapeutic interventions.
SEEK ID: https://fairdomhub.org/people/16
Location:
Germany
ORCID: Not specified
Joined: 4th May 2009
Expertise: Molecular microbiology, bacterial physiology, stress adaptation of Gram-positiv bacteria, application of functional genomics technologies in microbiology
Tools: Transcriptomics, molecular biology techniques, microbiology techniques, gel-based and gel-free proteomics, analysis of functional genomics data
Their tagsRelated items
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
BaCell-SysMO 2 Modelling carbon core metabolism in Bacillus subtilis – Exploring the contribution of protein complexes in core carbon and nitrogen metabolism.
Bacillus subtilis is a prime model organism for systems biology approaches because it is one of the most advanced models for functional genomics. Furthermore, comprehensive information on cell and molecular biology, physiology and genetics is available and the European Bacillus community (BACELL) has a well-established reputation for applying ...
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=53
Systems Biology of a genetically engineered Pseudomonas fluorescens with inducible exo-polysaccharide production: analysis of the dynamics and robustness of metabolic networks
Programme: SysMO
Public web page: http://www.sysmo-alginate.net/
Recent studies revealed the unsuspected complexity of the bacterial transcriptome but its systematic analysis across many diverse conditions remains a challenge. Here we report the condition-dependent transcriptome of the prototype strain B. subtilis 168 across 104 conditions reflecting the bacterium's life-styles. This data set composed of 269 tiling array hybridizations allowed to observe ~85% of the annotated CDSs expressed in the higher 30% in at least one hybridization and thus provide an ...
Creators: Leif Steil, Ulrike Mäder, Colin Harwood, Rick Lewis, Ruben Mars, Priyanka Nannapaneni, Praveen kumar Sappa, Joerg Stuelke, Jan Maarten van Dijl, Michael Hecker, Uwe Voelker
Submitter: Leif Steil
External Link
List of protein identified proteins in SPINE experiment.
Creators: Joerg Stuelke, Uwe Voelker
Submitter: Leif Steil
Download
Abstract (Expand)
Authors: , Annette Wensing, Margot Brosius, , ,
Date Published: 24th Nov 2012
Publication Type: Not specified
Abstract (Expand)
Authors: Andrea Wünsche, Elke Hammer, , , Andreas Burkovski, ,
Date Published: 20th Apr 2012
Publication Type: Not specified
Abstract (Expand)
Authors: Pierre Nicolas, , Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, , Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, , Wolfram Liebermeister, Anika March, , , David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, , Franck Samson, Marc Schaffer, Benno Schwikowski, , , Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, , , , Philippe Bessières, Philippe Noirot
Date Published: 3rd Mar 2012
Publication Type: Not specified
Abstract (Expand)
Authors: , , , , Georg Homuth, ,
Date Published: 2012
Publication Type: Not specified
Abstract (Expand)
Authors: Manuel Liebeke, Kirsten Dörries, Daniela Zühlke, Jörg Bernhardt, Stephan Fuchs, Jan Pané-Farré, Susanne Engelmann, , Rüdiger Bode, Thomas Dandekar, Ulrike Lindequist, ,
Date Published: 1st Apr 2011
Publication Type: Not specified
Abstract (Expand)
Authors: , Susanne Sievers, Daniela Zühlke, Judith Kuzinski, , Jan Muntel, Bernd Hessling, Jörg Bernhardt, Rabea Sietmann, , , Dörte Becher
Date Published: 11th Mar 2011
Publication Type: Not specified
Abstract (Expand)
Authors: Frederik M Meyer, Jan Gerwig, Elke Hammer, Christina Herzberg, Fabian M Commichau, ,
Date Published: 20th Aug 2010
Publication Type: Not specified
Abstract (Expand)
Authors: Hanne-Leena Hyyryläinen, , Kathleen Dahncke, Milla Pietiäinen, Pascal Courtin, Marika Vitikainen, Raili Seppala, Andreas Otto, Dörte Becher, Marie-Pierre Chapot-Chartier, , Vesa P Kontinen
Date Published: 4th May 2010
Publication Type: Not specified
Abstract (Expand)
Authors: Nico Pietack, Dörte Becher, Sebastian R Schmidl, Milton H Saier, , Fabian M Commichau,
Date Published: 13th Apr 2010
Publication Type: Not specified
Abstract (Expand)
Authors: Katrin Gunka, , Fabian M Commichau, Christina Herzberg, Cecilia Rodrigues, Lorraine Hewitt, , Jörg Stülke
Date Published: 22nd Feb 2010
Publication Type: Not specified
Abstract (Expand)
Editor:
Date Published: 12th Feb 2010
Publication Type: Not specified
Abstract (Expand)
Authors: Christoph R Lammers, , Arne G Schmeisky, Sebastian F Roppel, Ulrike Mäder, ,
Date Published: 3rd Dec 2009
Publication Type: Not specified
Abstract (Expand)
Authors: Thijs R H M Kouwen, Allan K Nielsen, Emma L Denham, Jean-Yves F Dubois, Ronald Dorenbos, Michael D Rasmussen, Wim J Quax, Roland Freudl,
Date Published: 30th Nov 2009
Publication Type: Not specified
Abstract (Expand)
Authors: Dierk-Christoph Pöther, Manuel Liebeke, Falko Hochgräfe, Haike Antelmann, Dörte Becher, , Ulrike Lindequist, Ilya Borovok, Gerald Cohen, Yair Aharonowitz,
Date Published: 16th Oct 2009
Publication Type: Not specified
Abstract (Expand)
Authors: Jessica C Zweers, Thomas Wiegert,
Date Published: 9th Oct 2009
Publication Type: Not specified
Abstract (Expand)
Authors: Thijs R H M Kouwen, Erik N Trip, Emma L Denham, Mark J J B Sibbald, Jean-Yves F Dubois,
Date Published: 8th Sep 2009
Publication Type: Not specified
Abstract (Expand)
Authors: Sacha A F T van Hijum, Marnix H Medema,
Date Published: 2nd Sep 2009
Publication Type: Not specified
Abstract (Expand)
Authors: Jijun Yuan, Jessica C Zweers, , Ross E Dalbey
Date Published: 16th Jun 2009
Publication Type: Not specified
Abstract (Expand)
Date Published: 11th Jun 2009
Publication Type: Not specified
Abstract (Expand)
Authors: , Sebastian F Roppel, Arne G Schmeisky, Christoph R Lammers,
Date Published: 26th May 2009
Publication Type: Not specified
