MESI-STRAT (University of Bergen) ; PoLiMeR - Polymers in the Liver: Metabolism and Regulation (University of Bergen) ; NAD COMPARTMENTATION (University of Bergen) ; Bergen(Ziegler lab) project AF-NADase (University of Bergen) ; NAMPT affinity (University of Bergen) ; NAD phylogeny (University of Bergen)
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Projects that do not fall under current programmes.
Projects: Manchester Institute for Biotechnology, ICYSB 2015 - International Practical Course in Systems Biology, iRhythmics, INBioPharm, EmPowerPutida, Systo models, MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, Multiscale modelling of state transitions in the host-microbiome-brain network, Extremophiles metabolsim, NAD COMPARTMENTATION, Agro-ecological modelling, Bergen(Ziegler lab) project AF-NADase, NAMPT affinity, Stress granules, Modelling COVID-19 epidemics
Web page: Not specified
MESI-STRAT: Systems Medicine of Metabolic-Signaling Networks -A New Concept for Breast Cancer Patient Stratification. Breast cancer is a complex disease with high prevalence in the European Union and world-wide. 75%-80 of the patients have estrogen receptor-positive (ER)-positive tumors and are treated with endocrine therapies. Endocrine therapies, which block ER-driven tumor growth, show high efficacy. Yet, a significant proportion of the patients will eventually relapse with metastatic breast ...
PoLiMeR is funded through the EU Marie Skłodowska-Curie Innovative Training Network (ITN), which drives scientific excellence and innovation. ITNs bring together universities, research institutes, industry and clinical partners from across the world to train researchers to doctorate level.
Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease ...
Most biological processes require energy and are tightly regulated. Energy is extracted from food supplies and eventually transformed into ATP, the universal energy carrier of the cell. These pathways consist of many reactions which involve NAD or NADP, small molecules which serve as intermediate energy transmitters. Vitamin B3 is essential for the synthesis of these nucleotides. Interestingly, the key molecules in energy transduction also have important roles in the regulation of all vital ...
Date Published: 6th Aug 2019
Publication Type: Journal
PubMed ID: 31341085
Citation: Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15957-15966. doi: 10.1073/pnas.1902346116. Epub 2019 Jul 24.
Date Published: 13th Nov 2015
Publication Type: Not specified
PubMed ID: 26432643
Citation: J Biol Chem. 2015 Nov 13;290(46):27644-59. doi: 10.1074/jbc.M115.654129. Epub 2015 Oct 2.
Date Published: 29th Nov 2013
Publication Type: Journal
PubMed ID: 24129579
Citation: J Biol Chem. 2013 Nov 29;288(48):34555-66. doi: 10.1074/jbc.M113.474908. Epub 2013 Oct 15.