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FBA result of flux distribution in butanol producing e.coli strain, which designed using RobOKoD.
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Created: 3rd Jun 2015 at 13:50
Last updated: 8th Dec 2015 at 15:05
Last used: 21st Feb 2019 at 09:34

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Projects: SysMO DB, Whole body modelling of glucose metabolism in malaria patients, Manchester Institute for Biotechnology, FAIRDOM, ICYSB 2015 - International Practical Course in Systems Biology, GenoSysFat, DigiSal, FAIRDOM user meeting, FAIRDOM Templates
Institutions: School of Computer Science, University of Manchester, Manchester Centre for Integrative Systems Biology, University of Manchester

Roles: Postdoc
Expertise: Data Management, Stoichiometric modelling, Kinetic modelling, Systems Biology, Metabolic Engineering, metabolic networks
Tools: COBRA toolbox, Python, Copasi, Matlab
Interested in systems + synthetic biology, biotechnology, mountaineering, swimming, running, and the occasional cup of tea. Once diagnosed as an ENFP.
Programme: Independent Projects
Public web page: Not specified
Organisms: Escherichia coli
RobOKoD algorithm was, designed then implemented as part of a study in RobOKoD: microbial strain design for (over)production of target compounds. (http://fairdomhub.org/publications/236). It was used to generate a strain of e.coli for producing butanol, that was then compared to an experimental strain. It was shown to perform better than similar methods (OptKnock, and RobustKnock).
Contributor: Natalie Stanford
Biological problem addressed: Model Analysis Type
Snapshots: No snapshots
Investigation: Designing a new way to predict engineering stra...
Study: Predicting engineering strategies for overprodu...
Organisms: No organisms
Models: iNS142 RobOKoD Redesigned Butanol Producing.
SOPs: RobOKoD SOP for Redesigning Butanol Producing S...
Data files: FBA result of RobOKoD designed e.coli strain.
Abstract (Expand)
Authors: Natalie Stanford, Millard P.,Swainston N.
Date Published: 24th Mar 2015
Journal: Front Cell Dev Biol
PubMed ID: 25853130
Citation: Front Cell Dev Biol. 2015 Mar 24;3:17. doi: 10.3389/fcell.2015.00017. eCollection 2015.