iNS142 RobOKoD Redesigned Butanol Producing. Version 1
Simulate Model on JWSButanol producing iNS142, redesigned using RobOKoD.
SEEK ID: https://fairdomhub.org/models/159?version=1
1 item (and an image) are associated with this Model:-
iNS142_ko.xml (XML document - 197 KB)
Organism: Not specified
Model type: Metabolic network
Model format: SBML
Execution or visualisation environment: Matlab
Model image: (Click on the image to zoom)
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Contributor and Creators
Views: 3114 Downloads: 199
Created: 3rd Jun 2015 at 13:44
Last updated: 31st Aug 2018 at 15:58
Last used: 18th Oct 2019 at 15:47
AttributionsNone
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Projects: SysMO DB, Whole body modelling of glucose metabolism in malaria patients, Manchester Institute for Biotechnology, FAIRDOM, ICYSB 2015 - International Practical Course in Systems Biology, GenoSysFat, DigiSal, FAIRDOM user meeting, FAIRDOM Templates
Institutions: School of Computer Science, University of Manchester, Manchester Centre for Integrative Systems Biology, University of Manchester
https://orcid.org/0000-0003-4958-0184
Interested in systems + synthetic biology, biotechnology, mountaineering, swimming, running, and the occasional cup of tea. Once diagnosed as an ENFP.
Programme: Independent Projects
Public web page: Not specified
Systems Biology studies the properties and phenotypes that emerge from the interaction of biomolecules where such properties are not obvious from those of the individual molecules. By connecting fields such as genomics, proteomics, bioinformatics, mathematics, cell biology, genetics, mathematics, engineering and computer sciences, Systems Biology enables discovery of yet unknown principles underlying the functioning of living cells. At the same time, testable and predictive models of complex
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Programme: Independent Projects
Public web page: http://www.icysb.se/
RobOKoD algorithm was, designed then implemented as part of a study in RobOKoD: microbial strain design for (over)production of target compounds. (http://fairdomhub.org/publications/236). It was used to generate a strain of e.coli for producing butanol, that was then compared to an experimental strain. It was shown to perform better than similar methods (OptKnock, and RobustKnock).
Contributor: Natalie Stanford
Biological problem addressed: Model Analysis Type
Snapshots: No snapshots
Abstract (Expand)
Authors: Natalie Stanford, P. Millard, N. Swainston
Date Published: 24th Mar 2015
Journal: Front Cell Dev Biol
