Expertise: Bioinformatics, Molecular Biology, Genomics, gene regulation
Tools: Genomics, Transcriptomics, Genetic modification
Projects: Not specified
Institutions: Not specified
Projects: HUMET Startup, EraCoBiotech 2 nd call proposal preparation, COVID-19 Disease Map
Institutions: geneXplain GmbH
https://orcid.org/0000-0001-6775-2467Expertise: Systems Biology, promoters and anhancers, gene regulation, signal transduction, drug targets
Tools: geneXplain platform, BioUML, R, c++
Alexander Kel received his Ph.D. in Bioinformatics, Molecular Biology and Genetics in 1990. He studied biology and mathematics at Novosibirsk State University and obtained his M.S. in biology with special focus on mathematical biology in 1985. He worked for 15 years at the Institute of Cytology and Genetics, Russia (ICG) holding positions as a programmer, scientist, senior scientist and Vice-Head of the Laboratory of Theoretical Molecular Genetics. In 1995, he won the Academician Belaev Award. ...
Projects: Noisy-Strep
Institutions: University of Groningen
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Gram positive bacteria (Bacillus, Lactococcus, Streptococcus), competence, sporulation, germination, antimicrobial peptides, phenotypic heterogeneity, bistability, C- and N- metabolism, gene regulation, stress responses, pathogens, virulence factors, metal ion homeostasis, protein secretion
Tools: Biochemistry, Genetics, Molecular Biology, Bioinformatics, Genomics, Transcriptomics, time lapse microscopy, FACS, genomic array footprinting
Group leader Molecular Genetics
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Microbiology, Genetics, Molecular Biology, Bacillus subtilis, translational control of gene expression, sporulation, phenotypic heterogeneity, bistability, gene regulation, stress responses, Signal transduction in Gram-negative bacteria; Synthetic Microbiology; Single cell gene expression; Regulatory networks; biochemistry; histidine ki..., regulation of gene expression, Systems Biology
Tools: Microbiology, Genetics, Molecular Biology, Genetic analysis, Genetic modification, Model organisms, Single Cell analysis, PCR, Fluorecence based reporter gene analyses/single cell analyses, Molecular biology techniques (RNA/DNA), time lapse microscopy, Time-lapse fluorescence microscopy Flow cytometry
Projects: COSMIC
Institutions: University of Nottingham
A molecular microbiologist with a passion for Clostridia! Interested in the development of more effective countermeasures (diagnosis, prevention & treatment) against pathogens, specifically Clostridium difficile and Clostridium botulinum as well as the exploitation of the medical and industrial properties of beneficial strains, specifically in cancer therapy and biofuel production
Projects: BaCell-SysMO
Institutions: University of Newcastle
Expertise: Microbiology, Molecular Biology, Gram positive bacteria (Bacillus, Systems Biology, Genetics)
Tools: Microbiology, Molecular Biology, Biochemistry and protein analysis, Cell biology, Genetic analysis, Genomics, Transcriptomics, Proteomics, Model organisms, Proteomics (2D-PAGE), gene regulation, DNA technology RNA technology Protein analysis Fermentation Mutagenesis, molecular biological techniques (RNA/DNA techniques), protein interaction studies
Optimisation of Bacillus subtilis for the secretion of heterologous proteins Therapeutic proteins (including those required for experimental purposes and clinical trials) are major products of biomanufacturing processes and considerable time and expense are expended to maximise the yield and quality of proteins produced in heterologous hosts. The production host of choice is the Gram-negative bacterium Escherichia coli for which many strains and expression systems have been developed. However, ...
Projects: BaCell-SysMO
Institutions: University of Erlangen-Nuernberg
Expertise: translational control of gene expression, gene regulation, protein-protein interactions, protein-RNA interactions, carbon catabolite regulation in Gram positive bacteria, Protein-DNA-interaction, expression systems for pro- and eukayotes, screening systems for nuclear transport and alternative splicing, inducible mammalian cell death.
CURRICULUM VITAE
Wolfgang Hillen Full Professor and Chairman of Microbiology Lehrstuhl für Mikrobiologie Institut für Biologie Friedrich-Alexander Universität Erlangen-Nürnberg Staudtstr. 5 91058 Erlangen, Fed. Rep. of Germany
Date of Birth: April 24, 1948 Place of Birth: Osnabrück, FRG Nationality: German Status: Married Children: Hauke Sven Hillen - May 17, 1987
RESEARCH AND PROFESSIONAL EXPERIENCE
Present Full Professor and Chairman of Microbiology at the Institute of Biology, Friedrich-Alexander ...
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Genetics, Molecular Biology, Microarray analysis, Bacillus subtilis, phenotypic heterogeneity, gene regulation, stress responses, protein secretion, functional protein expression, microscopy, fluorescence protein fusions (transcriptional and translational), localisation studies
Tools: Genetic modification, Transcriptomics, Microarray analysis, Fluorecence based reporter gene analyses/single cell analyses, Site-directed mutagenesis, Fluorescence microscopy, Flow cytometry, Immunofluorescence, transposon mutagenesis, Molecular biology techniques (RNA/DNA/Protein), DNA affinity chromatography, EMSA
PhD student. Analyzing CcpA affinity to cre boxes (catabolite responsive elements) and response of B. subtilis to membrane protein overproduction stress.