SPABBATS: A pathway-discovery method based on Boolean satisfiability that facilitates the characterization of suppressor mutants
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BiBTeXSeveral computational methods exist to suggest rational genetic interventions that improve the productivity of industrial strains. Nonetheless, these methods are less effective to predict possible genetic responses of the strain after the intervention. This problem requires a better understanding of potential alternative metabolic and regulatory pathways able to counteract the targeted intervention.
SEEK ID: https://fairdomhub.org/publications/155
PubMed ID: 21219666
Projects: BaCell-SysMO
Publication type: Not specified
Journal: BMC Syst Biol
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Date Published: 11th Jan 2011
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Created: 2nd May 2012 at 12:49
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Projects: BaCell-SysMO
Institutions: University of Goettingen
I'm a PhD student at the lab of Prof. Dr. Jörg Stülke. My main interest is to analyze the central metabolism of Bacillus subtilis using systems biology software. I have developed an algorithm to find short pathways connecting sets of metabolites and I'm also involved in SubtiWiki, the wiki for all genes of Bacillus subtilis (http://subtiwiki.uni-goettingen.de)
Projects: BaCell-SysMO
Institutions: University of Greifswald
I started to work with B. subtilis during my diploma thesis in Marburg, analyzing the gene expression pattern during sporulation and their control by the four sporulation sigma factors. This work was continued during my PhD thesis in Greifswald. In collaboration with Prof. Bremer and Prof. Marahiel in Marburg we also studied additional adaptation processes of B. subtilis, like the adaptation to low temperatur and high osmolarity. I am now working as a staff scientist in Prof. Völkers lab in ...
Projects: BaCell-SysMO
Institutions: University of Goettingen
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