Burgos, E. S., Ho, M. C., Almo, S. C., and Schramm, V. L. (2009) A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT. Proceedings of the National Academy of Sciences of the United States of America 106, 13748-13753
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Projects: NAMPT affinity, NAD phylogeny
Institutions: University of Bergen
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Organisms: Homo sapiens
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Submitter: Dorothee Houry
Investigation: 1 hidden item
Assays: FIGURE 2: Crystal structures of human NAMPT in complex with NA and PRPP,..., FIGURE 3: ATP is essential for NAMN formation by NAMPT, FIGURE 4: ATP indirectly stabilizes PRPP via pHis247., FIGURE 5: The deletion of the β1-β2 loop does not alter the geometry of ..., FIGURE 6: SAXS analysis of WT and Δ42-51 NAMPT.
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Submitter: Dorothee Houry
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: 1 hidden item
Organisms: No organisms
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