HepG2 oxygen consumption

Validation of model's ability to predict oxygen consumption flux as measured usign permeabilised cells in an Oroboros Oxygraph. Generates Fig. 2A in the associated publication.

Download "Model_notebooks.rar", unzip, and run: "2, generate-model-Oroboros-validation-[needs(1)]-20221109.nb" and "4, Fig2A-Oroboros-simulation-data-[needs-(1-2-and-3)]-20221109.nb" after running "1, generate-model-20221109.nb"

SEEK ID: https://fairdomhub.org/assays/2064

Modelling analysis

Christoff Odendaal

Projects: PoLiMeR - Polymers in the Liver: Metabolism and Regulation

Investigation: Mitochondrial fatty acid oxidation in human liver

Study: Model validation

Assay position:

Biological problem addressed: Validation

Organisms: Homo sapiens

help Creators and Submitter
Additional credit

Albert Gerding; Nicolette Huijkman; Marcel Vieira-Lara; Anne-Claire Martines


Views: 432

Created: 23rd Feb 2023 at 14:41

Last updated: 12th Jun 2023 at 13:30

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