ACAD activity partitioning

Testing the model's ability to predict palmitoyl-CoA and octanoyl-CoA dehydrogenation in human liver lysate, with and without anti-MCAD and anti-VLCAD antibodies. Generates Fig. 2 C and D in the associated publication. Data from Aoyama et al. (1995).

Downoad and unzip "Model_notebooks.rar" and run "6, Fig2C+D-ACAD-partitioning-validation-[needs-(1)]-20221109.nb" after running "1, generate-model-20221109.nb".

SEEK ID: https://fairdomhub.org/assays/2066

Modelling analysis

Christoff Odendaal

Projects: PoLiMeR - Polymers in the Liver: Metabolism and Regulation

Investigation: Mitochondrial fatty acid oxidation in human liver

Study: Model validation

Assay position:

Biological problem addressed: Validation

Organisms: No organisms

Activity

Views: 389

Created: 23rd Feb 2023 at 14:54

Last updated: 12th Jun 2023 at 13:30

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