Kinetic model for incubation (penkler2) Version 7
Simulate Model on JWSGlycolytic model for Plasmodium falciparum; closed system
SEEK ID: https://fairdomhub.org/models/138?version=7
3 items are associated with this Model:-
penkler2.xml (XML document - 99.9 KB)
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penkler2.nb (Mathematica Notebook - 1.06 MB)
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penkler2.dat (uuencoded file - 11.6 KB)
Organism: Not specified
Model type: Ordinary differential equations (ODE)
Model format: SBML
Execution or visualisation environment: JWS Online
Model image: No image specified
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Contributor and Creators
Views: 2556 Downloads: 130
Created: 11th Aug 2014 at 09:58
Last updated: 1st Jul 2015 at 10:19
Last used: 21st Oct 2018 at 18:18
AttributionsNone
Related items
orcid.org/0000-0003-2633-0537
Projects: PSYSMO, MOSES, SysMO DB, SysMO-LAB, SulfoSys, SulfoSys - Biotec, Whole body modelling of glucose metabolism in malaria patients, FAIRDOM, Molecular Systems Biology, COMBINE Multicellular Modelling, HOTSOLUTE, Steroid biosynthesis, Yeast glycolytic oscillations
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, University of Stellenbosch, School of Computer Science, University of Manchester, Stellenbosch University
Hypoglycaemia and lactic acidosis are key diagnostics for poor chances of survival in malaria patients. In this project we aim to test to what extent the metabolic activity of Plasmodium falciparum contributes to a changed glucose metabolism in malaria patients. The approach is to start with detailed bottom up models for the parasite and then merge these with more coarse grained models at the whole body level.
Programme: SARCHI: Mechanistic modelling of health and epidemiology
Public web page: Not specified
The investigation entails the construction and validation of a detailed mathematical model for glycolysis of the malaria parasite Plasmodium falciparum in the blood stage trophozoite form.
Snapshots: Snapshot 1
This study includes the experimental data for model validation and the model predictions of that data set.
Person responsible: Dawie Van Niekerk
Snapshots: No snapshots
SED-ML simulation: https://jjj.bio.vu.nl/models/experiments/penkler2aa_experiment-user/simulate
Contributor: Dawie Van Niekerk
Biological problem addressed: Model Analysis Type
Snapshots: No snapshots
