ExploreL. infantum promastigotes were administered with EC10 and EC50 concentrations of H80 and Miltefosine. Cells were fractionated into soluble (cyto), insoluble (membranes), and mitochondiral lysates, and analysed through LC-MS/MS Proteomics.
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MS_Proteomics_Raw data_H80_miltefosine.xlsx
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Created: 28th Oct 2025 at 10:18
Last updated: 28th Oct 2025 at 10:37
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Version 1 (earliest) Created 28th Oct 2025 at 10:18 by Giulia Malpezzi
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Projects: NMTrypI - New Medicines for Trypanosomatidic Infections, Mass spectrometry proteomics for biomarker discovery, Thymidylate synthase dimer dissociation, BioTarget Database, Compound Data, Giulia Malpezzi PhD raw data
Institutions: Università degli Studi di Modena e Reggio Emilia (UNIMORE)
https://orcid.org/0000-0002-0443-5402
Projects: Mass spectrometry proteomics for biomarker discovery, Supplementary Information 2 associated with the manuscript entitled " Label free Mass spectrometry proteomics reveals different pathways modulated in THP-1 cells infected with therapeutic failure and drug resistance Leishmania infantum clinical isolates", Supplementary Information 2 associated with the manuscript entitled "Label free Mass spectrometry proteomics reveals different pathways modulated in THP-1 cells infected with therapeutic failure and drug resistance Leishmania infantum clinical isolates", MS identification of L infantum proteins related to their drug resistance patterns for new drug targets identification and ecotoxicological evaluations of their environmental and interspecies impact, Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation, Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells, Drug Discovery and Biotechnology Standard Operating Procedures
Institutions: Università degli Studi di Modena e Reggio Emilia (UNIMORE), Università di Modena e Reggio Emilia
https://orcid.org/0000-0002-7244-7106
Junior researcher in Medicinal Chemistry
Projects that do not fall under current programmes.
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2022-2025 raw data Giulia PhD
Programme: Independent Projects
Public web page: Not specified
