Stressosome activation dynamics

The stressosome is an important sensor of environmental stresses in B. subtilis. It is formed by three protein types that form an icosahedral geometric protein complex. There are uncertanties how protein interactions take place, what the effects on the response behaviour of activation and inhibition of phosphorylation among proteins is, and what kind of proximal signal activates the stressosome in the first place. To answer these questions a computational modelling approach was developed. This approach need to reflect the strict geometric requirements of the stressosome including spatial constraints.

SEEK ID: https://fairdomhub.org/assays/236

Modelling Analysis

Ulf Liebal

Projects: BaCell-SysMO

Investigation: The transition from growing to non-growing Bacillus subtilis cells

Study: Controlled sigmaB induction in shake flask

Assay position:

Biological problem addressed: Signal Induction

Organisms: Bacillus subtilis

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Created: 5th Feb 2014 at 09:44

Last updated: 8th Nov 2017 at 15:21

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