Projects: SysMO-LAB, MOSES, PSYSMO, SulfoSys, SulfoSys - Biotec, EraCoBiotech 2 nd call proposal preparation, Make Me My Model, Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population, Modelling COVID-19 epidemics, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation, Xenophiles Systems Biology, Thermodynamics, Non equilibrium thermodynamics, Book on Thermodynamics, and kinetics, Teaching Alien Biology, Outdated material, Fusion-fission-mitophagy, Stochastics and bursting, Thermotables for biochemistry, Thermotables
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, VU University Amsterdam, University of Amsterdam, Systems Biology Amsterdam
https://orcid.org/0000-0002-0443-6114
Systems Biologist at University of Amsterdam, Free University Amsterdam, University of Manchester, Infrastructure Systems Biology.NL (ISBE.NL), Systems Biology Amsterdam.
Projects: BESTER
Institutions: PROCESSIUM
Process engineer since 2011 at Processium
Projects: TRANSLUCENT
Institutions: University of Applied Sciences Koblenz, Rhein Ahr Campus
Expertise: Ma
Tools: Computational and theoretical biology, Matlab, R, Biophysics, Thermodynamics, Machine Learning
I am working in the mathematical modeling of potassium homeostasis. In addition, we are developing tools and methods for the statistical analysis of biological data.
Excel file enabling computation of transformed reference chemical potentials. This is an excel file with two sheets. The first and most important of these is a computation facility calculating the transformed chemical potentials of more than 360 compounds of biochemical interest and 1200 forms thereof. This sheet uses the second sheet as the work horse of the computations. The magnitudes of various transformed reference potentials are listed in the file https://fairdomhub.org/data_files/9798, ...
Creators: Hans V. Westerhoff, Johann Rohwer, Peter J. Halling, Carsten Kettner, Yanhua Liu. HVW collected physical chemical reference potentials from the literature and developed and carried out all transformations thereto writing an excel file. YL checked the values obtained from the literature. PJH and HVW developed the CNPS gauge shifts. PJH checked the methodology used as well as the naming of the compounds. JR developed a Python program to compute the transformed reference potentials and thereby checked the values obtained by HVW. (A limited number of errors was identified and eliminated in this manner).
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
This is the abbreviated excel file used for the Thermotable calculations of Westerhoff et al (2026) FEBS J, in press entitled 'Metabolic thermodynamics: pertinent reference state and energy potentials' It is also Supplement S4 of that paper. As compared to the full file it addresses much fewer chemical species, but it does contain all the excel-based computation mechanisms, which are further explained in supplement S5 of the publication. The Table allows variously transformed and gauge-shifted ...
Creators: Hans V. Westerhoff, Johann Rohwer, Peter J. Halling, Carsten Kettner, Yanhua Liu
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
A Table of the standard metabolic potentials of over a thousand species and blends thereof, of biochemical importance, at two temperatures and 3 pHs. The Table is supplement S3 (Table 2) of _Westerhoff et al (2026) FEBS J. Metabolic thermodynamics: pertinent reference state and energy potentials. In that paper it is described how the metabolic potentials have been calculated from the standard chemical potentials of the corresponding chemical species.
These standard metabolic potentials are the ...
Creator: Hans V. Westerhoff
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
For more than a thousand chemical species of biological interest the table gives standard chemical, standard apparent chemical, and standard metabolic potentials:
- Standard chemical potentials: extracted from various literature references (data sources indicated below the Table)
- Standard apparent chemical potentials as the above standard chemical potentials but further transformed for H+ and ionic strength; for Alberty conditions (pH=7.14, pMg=3.57, I=0.25 M Osm=0 M) and for new biochemical ...
Creator: Hans V. Westerhoff
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Westerhoff H.V. and Van Dam K. (1987) Thermodynamics and control of biological free-energy transduction, Elsevier, Amsterdam ISBN: 0-444-80783-7 (U.S.)
This monograph gives the basis of both non equilibrium thermodynamics and metabolic control analysis in biology. It is rife with examples from bioenergetics.
It is also a compilation of mathematical equations and text and hence serves as a data file for mathematical biology and biological modelling
Creator: Hans V. Westerhoff
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
working document 31 January 2022 Context is the equilibrium constants measurement standardization
Creators: Hans V. Westerhoff, Peter Halling
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Work document version 31 January 2020
Creator: Hans V. Westerhoff
Submitter: Hans V. Westerhoff
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
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