**differential algebraic equations**'.

POSITION

Prof. Dr. Natal van Riel is Professor in Computational Modelling at the Academic Medical Center - University of Amsterdam (AMC - UvA) and Associate Professor in Systems Biology and Metabolic Diseases at the Department of Biomedical Engineering of the Eindhoven University of Technology (TU/e).

RESEARCH

My research applies mathematical modelling and computation to study metabolic diseases, in particular Metabolic Syndrome and co-morbidities. Systems biology approaches are developed for

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**Projects:** KOSMOBAC

**Institutions:** Max Planck Institute for Dynamics of Complex Technical Systems

**Expertise:** Mathematical and statistical modeling, bioreactor models, dynamics of biological networks, dynamics and control of biological networks, parameter estimation, Reactor models, Mathematical modelling, Bioinformatics, Molecular Biology

**Tools:** continuous cultivation, evaluation of process dynamics, DIVA, differential algebraic equations, linux, Material balance based modeling, stimulus response experiments, Microarray analysis, Matlab, Linear equations, ODE, Single Cell analysis, SBML, Model organisms, Transcriptomics, Computational and theoretical biology, Bioinformatics

I'm an engineer at the MPI Magdeburg and I'm working in the field of mathematical modeling, model verification, parameter identification, model analysis and experimental design. I'm involved in two projects, KOsmoBac and PSYSMO.

**Projects:** COSMIC, BaCell-SysMO

**Institutions:** University of Rostock

**Roles:** Postdoc

**Expertise:** Statistical Physics, Data analysis, Systems Biology, bistability, Physics, dynamics of biological networks, dynamics and control of biological networks, Mathematical modelling

**Tools:** data modelling, Dynamic modelling, Computational Systems Biology, C programming, Stochastic models, differential algebraic equations, Mathematica, Matlab, ODE, Computational and theoretical biology

Modelling of cellular signalling, Dynamic Motifs and Feedback, Quantitative Measures, Theoretical Aspects of Modelling Biological Systems

**Projects:** COSMIC, BaCell-SysMO, SYSTERACT, HUMET Startup, INCOME, BESTER, iRhythmics

**Institutions:** University of Rostock

**Expertise:** Data analysis
Mathematical modelling
Bioinformatics
Systems biology, dynamics of biological networks, dynamics and control of biological networks

**Tools:** quantitative western blot analysis, Stochastic models, quantitative western blot analyses, differential algebraic equations, stimulus response experiments, Mathematica, Matlab, ODE, Computational and theoretical biology

**Projects:** KOSMOBAC

**Institutions:** University of Aberdeen

My background is physics engineering & biomedical engineering. I did my PhD in Surrey on the modelling of response of mammalian cells to radiation of different qualities.

I have been working at the University of Aberdeen since November 2007 as a theoreticien research fellow of the KOSMOBAC project. We are investigating the homeostasis of ions in bacteria E. coli. I have been working at a model of the buffering capacity of the cytopplasm, arising from the presence of weak acids and bases. We

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**Expertise:** Dynamic optimization., Systems Biology, sensitivity analysis, Optimal experimental design, Mathematical modelling of biosystems and bioprocesses, dynamics and control of biological networks, parameter estimation

**Tools:** Dynamic modelling, Computational Systems Biology, Deterministic models, Stochastic models, parameter estimation, differential algebraic equations, Matlab, Partial differential equations, ODE

I am a postdoctoral researcher in the group of Julio Banga. My research is focused on computational systems biology with particular attention to the mathematical modelling of biosystems and bioprocesses. Some of the topics we address are:

- Parameter estimation

- Model identifiability

- Global sensitivity analysis

- Optimal experimental design

- Dynamic optimization

- Robust control of diffusion-reaction systems